Qiji Chemical
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2-Bromobutyric Acid

Qiji Chemical

2-Bromobutyric Acid
Specifications

HS Code

693724

Name 2-Bromobutyric acid
Molecular Formula C4H7BrO2
Molar Mass 167.001 g/mol
Appearance Colorless to light yellow liquid
Density 1.528 g/cm³
Boiling Point 207 - 208 °C
Melting Point 14 - 15 °C
Solubility In Water Slightly soluble
Flash Point 92.8 °C
Pka 2.95
Packing & Storage
Packing 2 - Bromobutyric Acid packaged in 1 - kg bottles for easy handling.
Storage 2 - Bromobutyric acid should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Store it separately from incompatible substances such as strong oxidizing agents and bases to prevent reactions. Label the storage container clearly for easy identification and safety.
Shipping 2 - Bromobutyric Acid is shipped in well - sealed, corrosion - resistant containers. Shipment follows strict chemical transport regulations, ensuring proper handling to prevent spills and exposure, with temperature control in some cases.
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2-Bromobutyric Acid 2-Bromobutyric Acid
General Information
Historical Development
2 - Bromobutyric Acid is an organic compound, and its historical development is very interesting. In the past, chemical research was at the beginning, and many chemists dedicated themselves to exploring new substances. For 2 - Bromobutyric Acid, early scholars gradually clarified its chemical properties through repeated experiments. At that time, the experimental conditions were simple and the research progress was slow. However, ancient chemists worked tirelessly, starting with basic reactions and gradually revealing its synthesis path. With the passage of time, technology has advanced, instruments have become more accurate, and synthesis methods have become more mature. Today, 2 - Bromobutyric Acid is widely used in medicine, chemical industry and other fields. This is the result of the efforts of chemists of all generations. Its historical development has witnessed the continuous evolution of chemistry.
Product Overview
2-Bromobutyric acid product overview
2-bromobutyric acid is also an organic compound. Its shape is colorless to light yellow liquid with a pungent smell. This substance is widely used in the field of organic synthesis.
In chemical reactions, 2-bromobutyric acid is often a key raw material. Due to the activity of bromine atoms in its structure, it can participate in many nucleophilic substitution reactions. With this property, chemists can prepare various organic compounds with specific structures and functions through carefully designed reaction paths.
From the perspective of preparation methods, it can be obtained by reacting butyric acid with bromine under appropriate conditions. When reacting, it is necessary to pay attention to the reaction temperature, the use of catalysts and other factors to ensure the high efficiency of the reaction and the purity of the product.
In terms of preservation, 2-bromobutyric acid should be stored in a cool and ventilated place, away from fire and heat sources. Because of its certain corrosiveness and irritation, it is necessary to be careful and take protective measures during operation to avoid harm to the human body. In short, 2-bromobutyric acid occupies an important position in the research and production practice of organic chemistry.
Physical & Chemical Properties
2 - Bromobutyric Acid is an organic compound. Looking at its physical and chemical properties, it is of great research value. Its appearance is colorless to light yellow liquid with a certain pungent odor. In terms of physical properties, the boiling point is about a specific range, which is related to the change of its state at different temperatures. And its density has a clear value, reflecting the compactness of the molecule.
In terms of chemical properties, the bromine atom in 2 - Bromobutyric Acid is active and easy to participate in substitution reactions. Because it contains carboxyl groups, it can be neutralized with bases and esterified with alcohols. Due to the characteristics of functional groups, it has a wide range of uses in the field of organic synthesis. It can be used as a key intermediate and can be converted into other compounds through many reactions, helping to develop new materials and drugs.
Technical Specifications & Labeling
2 - Bromobutyric Acid is an organic compound, which is crucial in terms of its technical specifications and identification (product parameters). Its appearance is often colorless to light yellow liquid, which needs to be accurately identified. It can be preliminarily identified by looking at its color and smelling its smell. Those that are colorless and have a special odor may be the product.
When it comes to technical specifications, purity is the first to bear the brunt. Its purity should meet specific standards, and the impurity content must be strictly controlled. Its purity can be measured by chemical analysis methods, such as gas chromatography. Furthermore, the boiling point is also a key parameter. 2 - The boiling point of Bromobutyric Acid has a certain range, which can be obtained through distillation experiments. Precise control of the boiling point can ensure product quality.
In terms of identification, the product packaging must be clearly marked with the name "2 - Bromobutyric Acid" to prevent confusion. It is also necessary to indicate the hazard label, because it is corrosive to a certain extent. In this way, the user can understand the characteristics and operate safely.
Preparation Method
To prepare 2-Bromobutyric Acid, the raw materials, production process, reaction steps and catalytic mechanism are the key. First, butyric acid is taken as the initial raw material, bromide is used as the brominating reagent, and in an appropriate reaction vessel, under the catalysis of red phosphorus or phosphorus tribromide, the substitution reaction is initiated.
The reaction steps are as follows: First, butyric acid and a small amount of red phosphorus are placed in a reactor, heated to a suitable temperature, and then bromide is slowly added dropwise. Red phosphorus and bromide interact first to form phosphorus tribromide, which prompts the α-hydrogen of butyric acid to be replaced by bromine atoms to form 2-Bromobutyric Acid. In this substitution reaction, phosphorus tribromide changes the reaction path, reduces the activation energy of the reaction, and
After the reaction is completed, the product is purified by distillation, extraction, recrystallization and other means to obtain pure 2-Bromobutyric Acid.
Chemical Reactions & Modifications
There is a chemical substance today, called 2 - Bromobutyric Acid. Looking at its chemical reaction and change is related to the importance of this substance.
To understand its chemical reaction, various conditions need to be investigated. The genera of temperature, pressure, and catalyst can all affect its reaction. Or when encountering a certain agent, it is easy to replace it, and the bromine position is easy; or when encountering other substances, it is eliminated, and the structure changes due to alkene bonds.
As for the change of its chemical properties, it is also interesting. Due to the nature of bromine atoms, this substance is acidic, which is different from that of butyric acid. Moreover, the electronegativity of bromine makes the molecular polar moment different, and it has a special state when it comes to nucleophilic and electrophilic responses.
The beauty of chemistry lies in the subtlety. 2 - Although Bromobutyric Acid is small, the exploration of its chemical adaptation and chemical properties can be used for the advancement of scholars and the prosperity of industry.
Synonyms & Product Names
The same name of 2-bromobutyric acid and the trade name
of 2-bromobutyric acid are organic compounds. The same name is also known as α-bromobutyric acid. The two refer to one and the other, both of which are specific chemical substances.
As for the trade name, it is widely used in the city, or it varies according to its characteristics and uses. To cover the world of chemical products, various merchants have created new product names in order to recognize their characteristics. However, regardless of the same name or trade name, the products involved are all 2-bromobutyric acid. Its chemical properties are unique, and it is often an important raw material in the field of organic synthesis. It can participate in various reactions to produce various compounds. Therefore, although the names are different, the essence is the same. Those who study chemistry in our generation should discern them, not be confused by different names, but recognize their true nature and make good use of them.
Safety & Operational Standards
2 - Bromobutyric Acid is an important chemical substance. During its experimental preparation and application, safety and operation standards are of paramount importance, which is related to the safety of the experimenter and endangers the success or failure of the experiment.
When preparing 2 - Bromobutyric Acid, it is first necessary to specify the properties of various reagents. The starting materials, catalysts, etc. used should be accurately understood for their chemical properties. If some reagents are highly corrosive, if they accidentally come into contact with the skin or eyes, they will cause serious burns. Therefore, when operating, be sure to wear strict protective equipment, such as acid and alkali-resistant gloves, protective glasses and laboratory clothes, to prevent damage caused by reagent spills.
The experimental operating environment should not be ignored. The proper operation of the fume hood is crucial because it can expel harmful gases generated during the experiment, such as hydrogen bromide and other irritating gases, in time to avoid their accumulation in the laboratory and endanger the health of the experimenter.
Furthermore, accurate control of the reaction conditions is essential. Factors such as temperature, reaction time and reactant ratio all have a significant impact on the yield and purity of 2-Bromobutyric Acid. When heating, the temperature should be raised slowly, and temperature changes should be closely monitored to prevent the reaction from getting out of control. If the temperature is too high, it may not only cause side reactions and reduce the purity of the product, but also lead to danger due to violent reactions.
During the product processing stage, specific specifications must also be followed. Standard procedures should be followed for the separation and purification of crude products. For example, when using the distillation method, it is necessary to ensure the tightness of the distillation device to prevent the leakage of solvents or products. At the same time, the treatment of waste should not be slack, and the waste containing bromine and other chemical substances should be properly classified and disposed according to environmental protection requirements to avoid environmental pollution.
When storing 2-Bromobutyric Acid, it should be placed in a cool, dry and well-ventilated place, away from fire sources and oxidants. Because of its certain chemical activity, improper storage may cause safety hazards.
In short, for the safe production and operation of 2-Bromobutyric Acid, it is necessary to start from the aspects of reagent cognition, operating environment, reaction conditions control, product handling and storage, and strictly follow the norms to ensure the safety and efficiency of the experiment.
Application Area
2 - Bromobutyric Acid is also a chemical product. Its use in the field of production, in the way of production, can be used to collect raw materials, help to synthesize, and cure general diseases. In the field of production, it may be used for research and development, to prevent diseases and protect the safety of crops. And in the process of chemical synthesis, it is often used in the process of production, in order to form a variety of useful compounds. Its characteristics are special, and its general use is the foundation. Therefore, 2 - Bromobutyric Acid has an important position in the fields of production, production, chemical synthesis, etc., and promotes all walks of life.
Research & Development
Taste the wonders of chemical industry, it is related to the change of all things. Jin Yan 2 - Bromobutyric Acid This object, in our research, is quite meaningful.
We have devoted ourselves to exploring its properties. Observe its structure, observe its reaction, and understand its combination with various things. The study of this substance, at the beginning, was like a maze, but it was relentlessly studied, and gradually obtained the essentials.
After repeated tests, it has been proved that it can be used as a key agent in the way of organic synthesis. Or help to form novel structures, or lead reactions in unique ways.
Its development potential cannot be underestimated. With time, we can expect to emerge in the fields of medicine and materials, add new color to the industry, and become the cornerstone of our research and development, so as to open up a new chemical industry and benefit the world.
Toxicity Research
The nature of taste and smell is related to human use, and the study of toxicology cannot be ignored. Today there is 2 - Bromobutyric Acid, and the study of its toxicity is crucial.
Husband 2 - Bromobutyric Acid may have its uses in various fields of chemical industry. However, its poison cannot be ignored. After various experiments, it can be known that it may hurt the body of living beings. When it enters the skin, it may cause redness, swelling and itching; when it enters the internal organs, it may disrupt the luck of qi and blood.
Therefore, to study its toxicity, multiple methods need to be taken simultaneously. Observe its impact on various organisms and measure its changes in different environments. And pass it on to everyone, so that they are aware of the danger, and when using it, they should be extra cautious to prevent the invasion of poison, so that they can protect their health and prosper.
Future Prospects
Taste the way of research is more expensive than looking to the future. Now View 2 - Bromobutyric Acid, its future prospects are quite promising.
In the field of medicine, it may be the cornerstone of the research and development of new agents. With its unique structure, it may be possible to make special drugs, cure various diseases, and save patients from sinking diseases.
In the road of chemical industry, there are also good opportunities. It can be used as raw materials for delicate synthesis, produce all kinds of novel materials, and be applied to all parties to add luster to industry.
Although there may be thorns in the road ahead, but uphold the heart of research and unremitting exploration. With time, we will be able to make 2 - Bromobutyric Acid shine brightly on the stage of the future, unleash its extraordinary capabilities, and become a magnificent cause for the well-being of the world and create a new environment.
Frequently Asked Questions
What are the main uses of Bromobutyric Acid?
2-Bromobutyric acid, which is a colorless to light yellow liquid, is irritating and has a wide range of uses in many fields of chemical industry.
First, in the field of organic synthesis, this is a key intermediate. It can be replaced by nucleophilic substitution, and bromine atoms are easily replaced by other groups, such as reacting with alcohols, which can generate corresponding ester compounds. Such esters are widely used in the fragrance industry and can give products a unique aroma. Reacting with amines can produce nitrogen-containing organic compounds. These compounds are of great significance in the field of drug synthesis, and some can be used as potential pharmaceutical active ingredients or important intermediates.
Second, in pharmaceutical chemistry, 2-bromobutyric acid can be reacted in a series of reactions to construct molecular structures with specific pharmacological activities. For example, some compounds synthesized from it have shown good prospects for the treatment of specific diseases and play an important role in the drug development process, helping researchers to explore more effective therapeutic drugs.
Third, in the field of materials science, polymer materials synthesized by 2-bromobutyric acid have special properties. For example, the polymers generated by its participation in copolymerization reactions may perform well in terms of solubility, thermal stability or mechanical properties, providing the possibility for the development of new high-performance materials to meet the diverse needs of different fields for material properties.
What are the Physical Properties of Bromobutyric Acid?
2-Bromobutyric acid is also an organic compound. It has many physical properties, let me talk about them one by one.
Looking at its properties, at room temperature, 2-bromobutyric acid is mostly colorless to light yellow liquid, and its appearance is clearly recognizable.
When it comes to the melting point, it is about -2 ° C. This temperature characteristic makes it change under specific environmental conditions, which affects its storage and application.
In terms of boiling point, it is usually in the range of 208 ° C to 210 ° C. The boiling point is related to the temperature node at which it is converted from liquid to gas during heating, and is crucial in chemical operations such as distillation and separation.
The density is about 1.66 g/cm ³. This value reflects the mass per unit volume. It is of great significance for operations involving substance measurement, mixing, etc., and is related to the reaction ratio and product quality.
Solubility is also an important property. 2-Bromobutyric acid is soluble in water, but its solubility is limited. At the same time, it is more soluble in organic solvents such as ethanol and ether. This solubility characteristic provides a basis for the selection of suitable solvents in the process of chemical synthesis, extraction and separation, and affects the reaction process and product purification.
Furthermore, 2-Bromobutyric acid has a certain smell, and its smell is pungent. When operating, it needs to be protected to avoid discomfort to the human body.
In summary, the physical properties of 2-bromobutyric acid, such as properties, melting point, boiling point, density, solubility, and odor, are interrelated, and are of great significance for the design and implementation of its application and related operations in chemical production, scientific research, and other fields.
What are the chemical properties of 2-Bromobutyric Acid?
2-Bromobutyric acid, which is active, has the characteristics of both halogenated hydrocarbons and carboxylic acids.
First of all, its halogenated hydrocarbons. Bromine atoms are highly active and can participate in many nucleophilic substitution reactions. In the case of alcohols, under the catalysis of bases, bromine atoms are easily replaced by alkoxy groups, forming a genus of esters. For example, when mixed with ethanol, with the help of sodium hydroxide, ethyl 2-ethoxybutyrate is produced, which is a method for organic synthesis of esters. In the case of ammonia or amines, bromine can also be replaced by amino groups to obtain organic compounds containing nitrogen. If it interacts with methylamine, 2-methylaminobutyric acid can be obtained, which is a key step in the synthesis of biologically active substances.
In addition, it has the property of carboxylic acid. It is acidic and can be neutralized with bases to form corresponding salts. React with sodium hydroxide to obtain sodium 2-bromobutyrate, which is used as an intermediate in some chemical processes. It can also be esterified with alcohols. Under acid catalysis, it forms methyl 2-bromobutyrate with methanol. This ester is often used as a fragrance or raw material for organic synthesis.
In addition, the α-hydrogen of 2-bromobutyric acid, due to the influence of carboxyl groups and bromine atoms, also increases its activity. Under appropriate reagents and conditions, substitution reactions can occur to introduce new functional groups into molecules, expand its path in organic synthesis, and play an extraordinary role in the construction of complex organic structures.
In summary, 2-bromobutyric acid has a wide range of uses in the field of organic synthesis due to its unique structure, both halogenated hydrocarbons and carboxylic acids. It can produce a variety of organic compounds and is an important raw material for chemical, pharmaceutical and other industries.
What are the Synthetic Methods of Bromobutyric Acid?
There are various ways to prepare 2-bromobutyric acid. First, it can be obtained by the reaction of butyric acid and bromine under the catalysis of red phosphorus or phosphorus tribromide. The reaction process is as follows: red phosphorus first interacts with bromine to form phosphorus tribromide, which then reacts with butyric acid, and replaces the α-hydrogen of butyric acid with bromine atoms to obtain 2-bromobutyric acid. The reaction is roughly as follows: when butyric acid encounters phosphorus tribromide, after a series of changes, the α-hydrogen is replaced by bromine to form 2-bromobutyric acid and phosphoric acid.
Second, it can be prepared by the reaction of 2-hydroxybutyric acid with hydrobromic acid. In this process, the hydroxyl group of 2-hydroxybutyric acid is replaced by the bromine atom of hydrobromic acid. The mechanism is that the bromine ion in hydrobromic acid nucleophilically attacks the carbon atom connected to the hydroxyl group, and the hydroxyl group leaves in the form of water, resulting in 2-bromobutyric acid.
Furthermore, the addition reaction of butenic acid with hydrogen bromide can also be obtained. The double bond of butenic acid is added to hydrogen bromide, following the Markov rule. Hydrogen is added to the double bond carbon containing more hydrogen, and bromine is added to the double bond carbon containing less hydrogen to generate 2-bromobutyric acid. This is a common method for preparing 2-bromobutyric acid. Each method has its own advantages and disadvantages, and it is necessary to choose the best one according to the actual situation.
2-Bromobutyric Acid Storage and Transportation
2-Bromobutyric acid is an organic compound, which is corrosive and irritating. When storing and transporting, the following points should be paid special attention to:
First, the storage container. When storing in containers made of corrosion-resistant materials, such as glass or specific plastic materials. Glass containers are chemically stable and do not react easily with 2-bromobutyric acid, so you need to be careful to prevent breakage. Plastic materials should be selected to resist its corrosion, and ensure that the container is well sealed to prevent leakage.
Second, the storage place. It should be placed in a cool, dry and well-ventilated place. Avoid high temperatures. If 2-bromobutyric acid is heated or chemically reacts, its stability will decrease and even cause danger. Humid environment or cause its hydrolysis and other reactions, which damage the quality. Good ventilation can prevent the accumulation of harmful gases.
Third, transportation regulations. When transporting, it must be properly packaged in accordance with relevant regulations. The outer package should be marked with warning signs, such as "corrosive items", so that the transporter can understand its dangerous characteristics and operate prudently. During transportation, vibration and impact should also be prevented to avoid damage to the container and leakage.
Fourth, the importance of isolation. Do not mix with oxidants, strong bases and other substances. 2-Bromobutyric acid encounters with oxidants or undergoes violent oxidation reactions, and is prone to neutralization and other reactions with strong bases, which can cause danger.
Fifth, protective measures. When storing and transporting personnel, it is necessary to wear appropriate protective equipment, such as acid and alkali-resistant gloves, protective glasses, protective clothing, etc., to prevent skin and eye contact. If accidentally touched, rinse with plenty of water quickly and seek medical attention according to the injury.