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2-Bromopropionic Acid

Qiji Chemical

2-Bromopropionic Acid
Specifications

HS Code

122917

Name 2-Bromopropionic Acid
Chemical Formula C3H5BrO2
Molar Mass 152.974 g/mol
Appearance Colorless to light yellow liquid
Odor Pungent odor
Density 1.707 g/cm³ at 25 °C
Melting Point 24 - 26 °C
Boiling Point 203 - 204 °C
Solubility In Water Soluble
Pka 2.93
Flash Point 96 °C
Vapor Pressure 0.014 mmHg at 25 °C
Packing & Storage
Packing 100 - gram bottles of 2 - Bromopropionic Acid, securely sealed for safe storage.
Storage 2 - Bromopropionic acid should be stored in a cool, dry, well - ventilated area, away from heat and ignition sources. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials like glass. Store it separately from oxidizing agents, bases, and reducing agents to prevent chemical reactions. Ensure proper labeling for easy identification and safety.
Shipping 2 - Bromopropionic Acid should be shipped in tightly - sealed containers, compliant with hazardous chemical regulations. Ensure proper labeling indicating its corrosive nature. Ship via approved carriers using appropriate safety precautions during transit.
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2-Bromopropionic Acid 2-Bromopropionic Acid
General Information
Historical Development
2 - Bromopropionic Acid is an organic compound with an interesting history. In the past, at the beginning of chemical research, many substances were waiting to be explored. 2 - Bromopropionic Acid was first discovered in the laboratory, when chemists focused on various reactions and accidentally achieved this result. Early understanding was limited to its basic properties. Over time, technology has advanced and synthesis methods have been continuously optimized. From simple and crude methods, to precise and efficient paths. In-depth research has revealed that it has great potential in the field of organic synthesis, and can be used as a key intermediate to participate in the construction of a variety of complex compounds. The historical development of this compound is like a microcosm of the long road of chemical exploration, witnessing the gradual improvement of human cognition and control of the material world.
Product Overview
2 - Bromopropionic Acid is also a chemical substance. Its characteristic is that it is a propionic acid derivative containing bromine. Its color or color is high, and it is often mixed with liquid, which has a certain quality and a smell.
This substance is used in the field of chemical synthesis. It can be used as a kind of chemical compound. It is used in the synthesis, or to help with special effects. It may also become an important component in the research.
However, this substance also needs to be properly treated. Because of its certain decay, if it is accidentally attached to the skin or eyes, it will cause harm. When operating, you must follow safety standards and prevent damage to avoid danger. In addition, 2 - Bromopropionic Acid has its important position in chemical research and engineering, so it should be used with caution.
Physical & Chemical Properties
2 - Bromopropionic Acid, organic compound also. Its physical properties, at room temperature is colorless to light yellow liquid, with pungent odor, soluble in water, ethanol, ether and other organic solvents, boiling point is about 203 - 204 ℃, melting point is about - 15 ℃, density than water.
In terms of its chemical properties, because it contains bromine atoms and carboxyl groups, chemical activity is quite high. Bromine atoms can undergo nucleophilic substitution reactions, such as with alcohols, amines and other nucleophiles, bromine is substituted to form new compounds. Carboxyl groups are acidic, and can neutralize with bases to form corresponding carboxylic salts and water. It can also be esterified with alcohols to form ester compounds. Its chemical properties are widely used in the field of organic synthesis, and can be used to prepare a variety of important organic compounds, which are of great value in the fields of drug synthesis and materials science.
Technical Specifications & Labeling
There is now a method for making 2 - Bromopropionic Acid, and its technical regulations and identification (product parameters) are the key. The system of this product needs to follow a strict method. Prepare all kinds of raw materials first, according to their proportions, carefully put them into the device. Temperature and pressure are fixed and cannot be ignored. When reacting, observe its changes and abide by its regulations.
After it is made, check its quality. Looking at its color, it should be pure and free of impurities; measuring its quality, it is in line with the established standards. In the logo, its characteristics, such as the degree of melting and the geometry of purity, must be confirmed. In this way, a qualified product can be obtained to meet all the needs, meet the requirements of technical regulations and labels, and the user can be safe.
Preparation Method
To prepare 2-Bromopropionic Acid, first take propionic acid as raw material. React with bromine, and under the condition of light or heating, α-hydrogen in propionic acid can be replaced by bromine atoms. The reaction process is as follows: When irradiated or heated, the bromine molecule is split into a bromine radical, which captures α-hydrogen propionic acid to generate α-propionic acid radical, which then interacts with the bromine molecule to obtain 2-Bromopropionic Acid.
Reaction steps: Put propionic acid in the reactor, pass bromine, heat up and keep the light. After the reaction, the product is purified through post-treatment steps such as distillation and extraction. In order to promote the efficient reaction, the temperature, bromine dosage and light intensity can be adjusted moderately. In addition, the reaction equipment must be corrosion-resistant, and attention should be paid to tail gas treatment to prevent the escape of harmful gases such as hydrogen bromide.
Chemical Reactions & Modifications
Taste the wonders of chemical industry, it is related to the change of all things. Today there are 2 - Bromopropionic Acid. Its chemical reaction and change are worth studying.
To observe its reaction, it often follows the rules of chemistry, or combines with other things, or decomposes itself. Its change is also based on the principles of chemistry. If you want to improve its nature, you must understand its response. Such as changes in temperature and pressure, and the addition of catalysts, it can make the reaction speed and fruit easier.
If you want to change its nature, you can explore new ways. Try different agents, participate in the reaction, and observe its changes. Or you can get different qualities, different from before. After repeated research and testing, or optimization methods can be found to make this chemical have better performance, which is helpful to all industries. This is our wish to study the chemical response and change of this substance.
Synonyms & Product Names
2 - Bromopropionic Acid, that is, 2-bromopropionic acid, is very important in the chemical industry. Its synonymous name is also known as α-bromopropionic acid. In the industry, different trade names are also different.
Guanfu Chemical, the same substance often has synonymous names due to different uses and characteristics, which is easy to distinguish and use. 2-bromopropionic acid is a key raw material in the field of organic synthesis. It participates in many reactions and can produce a variety of products.
Merchants often give unique trade names to recognize the characteristics of their products or due to marketing considerations. Although the names are different, they are all 2-bromopropionic acid. For researchers, it is necessary to clarify their synonyms and various trade names in order to choose materials and study reactions accurately and without confusion.
Safety & Operational Standards
2-Bromopropionic acid safety and operating specifications
Fu 2-bromopropionic acid is an important substance in chemical research. If you want to use this material, you must first clarify its safety and operating specifications in order to ensure the smooth experiment and protect the health of the human body.
#1. Storage essentials
2-bromopropionic acid should be placed in a cool, dry and well-ventilated place. It must be kept away from fire and heat sources to prevent it from being decomposed by heat and causing danger. And it should be stored separately from oxidizing agents and alkalis, and must not be mixed. Because it is easy to react with various substances, it will cause harm. In the storage place, when suitable materials are available to contain leaks for emergencies.
#2. Rules of Operation
When operating 2-bromopropionic acid, the experimenter must wear appropriate protective clothing, gloves and goggles to prevent it from touching the skin and eyes and causing burns. In the operation room, good ventilation must be carried out. If conditions permit, a local exhaust device should be used to discharge harmful gases in time and not gather in the room.
When using 2-bromopropionic acid, the action should be steady and light to avoid it spilling. If it spills accidentally, do not panic. In the event of a small amount of leakage, it can be mixed with sand, dry lime or soda ash and collected in a dry, clean and covered container. A large amount of leakage should be built into a dike or dug for containment, and transferred to a tanker or special collector by pump, recycled or transported to a waste treatment site for disposal.
During the experiment, do not eat, drink or smoke. After the operation, wash your hands, face, and clothes in time to prevent the residual 2-bromopropionic acid from endangering health.
In short, when using 2-bromopropionic acid in chemical research, you must strictly abide by safety and operating standards, and do not slack at all, so that the research is safe and successful.
Application Area
2-Bromopropionic acid is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it is often the key raw material for the preparation of special drugs. With its unique chemical properties, it can participate in many reactions and help form pharmaceutical ingredients with specific curative effects.
In the field of agricultural chemicals, 2-bromopropionic acid also has wonderful uses. It can be used as an important intermediate for the synthesis of some efficient pesticides. Through its reaction with other compounds, it can create pesticide products that can effectively control pests and diseases and protect crop growth.
Furthermore, in the fine chemical industry, this compound can be used to synthesize special fragrances or additives. Because it can give products unique characteristics and improve product quality and value, it is also highly valued in this field. In short, 2-bromopropionic acid plays an important role in various application fields and promotes the development of related industries.
Research & Development
I am dedicated to the research of 2 - Bromopropionic Acid, which has unique properties and great potential in various fields of chemical industry. Initially, explore its synthesis method, and through many experiments, observe the influence of various reaction conditions, such as temperature, catalyst dosage, etc. Strive to obtain an efficient and pure synthesis path.
Also study its physicochemical properties, measure its melting point, boiling point, solubility, etc. To clarify its properties in different environments, lay the foundation for subsequent applications.
As for its development, it is hoped to expand the scope of application. In the field of medicine, it can be used as an intermediate to assist in the development of new drugs; in the field of materials, it may be able to improve material properties. I will make unremitting research, hoping that this material can have a broader prospect, contribute to the academic and industrial circles, and promote progress in related fields.
Toxicity Research
2 - Bromopropionic Acid, that is, 2 - bromopropionic acid, the toxicity study of this substance is quite important. Looking at the past toxicological investigations, it can be known that it has certain toxicity.
It may disturb the biochemical order in living things. After entering the body, it may be involved in various biochemical reactions, disrupting the metabolism of cells and damaging the structure of cells.
Taste all kinds of creatures as a test, apply this substance. It can be seen that the tested creatures may have abnormal physiological conditions. Such as slow movement, reduced eating or even life-threatening.
And this substance may have accumulative properties and is difficult to dissolve quickly in the environment. If it accumulates between water and soil for a long time, it is taken by organisms and goes up the food chain, its harm may gradually appear in high-level organisms, and eventually the ecological balance will be affected. Therefore, the study of the toxicity of 2-Bromopropionic Acid should be continuous and in-depth, as the basis for protection.
Future Prospects
2 - Bromopropionic Acid This object is promising. Its characteristics are unique, but its use is limited.
Today, the research has not been completed, but the future is not clear. It can be used in the field of development, or in the raw materials of production, to eliminate diseases and improve health. It can also be used in the synthesis of new things, to open up the unknown.
There is no obstacle in the next step, but the heart of the human being is like a rock. If you give it a long time, the skill will be refined, and it will be profitable. 2 - Bromopropionic Acid will definitely be able to show its brilliance and make great contributions to the world. Its unparalleled prosperity can be expected, and it will definitely be able to create new situations and promote new steps.
Frequently Asked Questions
What are the main uses of 2-bromopropionic acid?
The main use of 2-% cyanopropionic acid is as a raw material for organic synthesis. In the field of organic synthesis, it has a wide range of uses.
First, it can be used to synthesize heterocyclic compounds. Heterocyclic compounds play a crucial role in the fields of medicine, pesticides, dyes, etc. With 2-% cyanopropionic acid as the starting material, through a series of chemical reactions, various heterocyclic systems with unique structures can be ingeniously constructed. For example, by cyclization with suitable reagents, heterocyclic compounds containing heteroatoms such as nitrogen and oxygen can be prepared. Such compounds often exhibit unique biological activities and can provide key intermediates for the development of new drugs.
Second, it also has important uses in the preparation of special polymers. 2-% cyanopropionic acid can participate in the polymerization reaction to form polymers with special properties. Functional groups such as cyano and carboxyl groups in its molecules endow polymers with unique chemical and physical properties. For example, in the synthesis of some high-performance engineering plastics, the introduction of 2-% cyanopropionic acid structural units can improve the heat resistance, mechanical strength and other properties of polymers, and broaden their applications in high-end fields such as aerospace and electronics.
Third, in the synthesis of fine chemicals, 2-% cyanopropionic acid is also often a key raw material. In the preparation process of fine chemicals such as fragrances and additives, their special functional group properties can be used to achieve precise synthesis of target products. Through appropriate reaction conditions and reagent selection, their functional groups can be modified and converted to obtain fine chemicals with specific aromas or functions to meet the needs of different industries.
Furthermore, in the study of organic synthetic chemistry, 2-% cyanopropionic acid is a commonly used synthetic building block, providing an important material basis for chemists to explore new reactions and new methods. Through various chemical transformations, new paths for organic synthesis can be opened up, the structural diversity of organic compounds can be enriched, and the continuous development and progress of organic synthetic chemistry can be promoted.
What are the physical properties of 2-bromopropionic acid?
2-% carboxybutyric acid has various physical properties. It is a colorless to pale yellow liquid with strong hygroscopicity. Looking at its properties, under room temperature and pressure, it is in a liquid state, flowing freely, just like the water of a babbling stream, touching it warmly.
When it comes to boiling point, it is about 200 degrees Celsius. This is due to the force between molecules. To make it boil, it needs a considerable amount of energy to break free from the bonds between molecules and turn into gaseous ascension. Its melting point is also low, and it is difficult to solidify at room temperature, usually maintaining the shape of a liquid state.
As for the density, it is slightly heavier than water. If it is co-placed with water, it can be seen that it slowly sinks underwater, like a pearl falling into the abyss. Its solubility is also a major characteristic, and it can be miscible with many organic solvents such as water, alcohol, ether, etc. It is just like water emulsion, and it blends seamlessly. This is because the hydrophilicity of the carboxyl group in the molecular structure allows it to form hydrogen bonds with water molecules, so it can be soluble in water and also miscible with organic solvents containing similar functional groups.
In addition, 2-% carboxybutyric acid still has a certain degree of acidity, which originates from the existence of carboxyl groups. Carboxybutyric acid can partially ionize hydrogen ions, showing the sign of acidity in solution, and can neutralize with alkali substances, just like yin and yang, and transform into new substances. Although its smell is not strong, it also has a unique smell, like an elegant flower fragrance, which is faint and audible, but not pungent and disturbing. All these physical properties are inherent to 2-% carboxybutyric acid, which has its unique uses in chemical, pharmaceutical and other fields.
Is the chemical properties of 2-bromopropionic acid stable?
2-% carboxybutyric acid is slightly safer in nature. It is an organic acid containing carboxyl groups, and can develop various reactions under specific conditions.
At room temperature and pressure, 2-% carboxybutyric acid is mostly liquid and has certain stability. In case of high temperature, strong oxidizing agent, etc., its stability may be affected.
If it is at high temperature, the bonds in the 2-% carboxybutyric acid molecule can be energized and vibrated, causing the bond to break. If heated to a certain temperature, the carboxyl group may undergo a decarboxylation reaction, and the carbon dioxide will be lost and the structure will be changed. It says: "If it is too hot, the carboxyl group will be separated, the carbon and oxygen will be lost, and it will be transformed into new substances."
2 -% carboxybutyric acid is also difficult to stabilize in the presence of strong oxidizing agents. Because it contains oxidizable groups, the oxidizing agent grabs its electrons and causes the change of its chemical state. If it encounters a strong oxidizing agent of permanganate, it can cause the oxidation and cracking of the carbon chain and damage its original structure. The so-called "strong oxygen is in the presence of strong oxygen, grabs electrons and breaks its chain, and its chemical properties change."
However, under normal conditions, without special reagents and conditions, 2 -% carboxybutyric acid can be relatively stable. The force within the molecule maintains the structure, making it relatively stable. Therefore, the stability of 2 -% carboxybutyric acid varies depending on the environment and conditions. Under normal conditions at room temperature, it is still stable, but in case of special cases, it is easy to change its properties.
What are the preparation methods of 2-bromopropionic acid?
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1.2-Ethyl bromopropionate hydrolysis method
Take an appropriate amount of ethyl 2-bromopropionate, place it in a reactor, add a sufficient amount of sodium hydroxide solution, use ethanol as a solvent, and carry out the hydrolysis reaction under mild heating conditions. This reaction mechanism is that the ester groups are hydrolyzed in an alkaline environment to generate corresponding carboxylic salts and alcohols. Specifically, the ethoxy group in ethyl 2-bromopropionate is replaced by a hydroxyl group to form sodium 2-bromopropionate, and ethanol escapes at the same time. After the reaction is complete, dilute sulfuric acid is slowly added dropwise to the system for acidification. Sodium 2-bromopropionate is acidified and converted into 2-bromopropionic acid. Then a series of separation and purification methods such as distillation and extraction can be used to obtain high-purity 2-bromopropionic acid.
2. Acrylonitrile and hydrogen bromide addition method
In a suitable reaction vessel, acrylonitrile gas is introduced, and hydrogen bromide gas is slowly introduced. Under the action of initiators such as peroxides, the addition reaction occurs according to the anti-Markov rule. In this process, bromine atoms are added to the carbon atoms in acrylonitrile connected to the cyanide group to form 2-bromopropionitrile. Subsequently, 2-bromopropionitrile is hydrolyzed in an acidic or alkaline environment, and the cyanyl group is gradually converted into a carboxyl group, eventually generating 2-bromopropionic acid. The key to this method lies in the control of the addition reaction conditions and the precise operation of the hydrolysis step to ensure the smooth progress of the reaction and obtain a higher yield.
3. Propionic acid bromination
Using propionic acid as raw material, in the presence of catalysts such as red phosphorus or phosphorus tribromide, it undergoes a substitution reaction with bromine elemental substance. Under the action of the catalyst, the α-hydrogen atom in the propionic acid molecule is replaced by the bromine atom to generate 2-bromopropionic This reaction process requires strict control of the reaction temperature and the amount of bromine to avoid the occurrence of side reactions such as excessive bromination. After the reaction, the product is purified by vacuum distillation, recrystallization and other methods to obtain pure 2-bromopropionic acid.
What should be paid attention to when storing and transporting 2-bromopropionic acid?
Dicyanoacetic acid is active and toxic. It must be carefully stored and transported.
When storing, the first thing to do is to choose a cool, dry and well-ventilated place. Because it is afraid of heat and moisture, if it is in a high temperature and humid environment, it is easy to decompose and deteriorate, and even cause dangerous changes. The temperature of the warehouse should be controlled within a specific range to prevent it from being uneasy if the temperature is too high. And it should be placed separately from oxidizing agents, reducing agents, acids, alkalis and other chemicals, because it is easy to have violent chemical reactions with them and cause accidents. At the same time, the storage place needs to be prepared with suitable materials to contain leaks, so as to prevent accidental leakage, and it can be properly handled in time to avoid the spread of harm.
When transporting, appropriate packaging must be used. Packaging materials must have good sealing and corrosion resistance to ensure that dicyanoacetic acid does not leak or react with foreign objects during transportation. Transportation vehicles should also be clean, dry, and not mixed with the above-mentioned chemicals that can react with it. Transportation personnel must be professionally trained and familiar with the dangerous characteristics of dicyanoacetic acid and emergency treatment methods. During transportation, pay close attention to environmental factors such as temperature and humidity to avoid direct sunlight and turbulence and vibration to ensure a smooth and safe transportation process. If a leak occurs during transportation, the surrounding people should be evacuated immediately. It is strictly forbidden for fire to approach. Transportation personnel need to take emergency measures quickly to collect the leak with special tools and dispose of it properly to prevent environmental pollution and safety accidents. Overall, the storage and transportation of dicyanoacetic acid is related to safety and the environment, and must not be slack at all. It must be strictly implemented in accordance with regulations.