Qiji Chemical
Products

Bromoacetic Acid

Qiji Chemical

Specifications

HS Code

438792

Name Bromoacetic acid
Chemical Formula C2H3BrO2
Molar Mass 138.95 g/mol
Appearance Colorless to slightly yellow crystals or liquid
Odor Pungent
Density 1.93 g/cm³ (20 °C)
Melting Point 50 - 52 °C
Boiling Point 208 - 209 °C
Solubility In Water Soluble
Pka 2.90
Flash Point 108 °C
Hazard Class Corrosive
Packing & Storage
Packing 100g of Bromoacetic Acid in a sealed, corrosion - resistant chemical - grade bottle.
Storage Bromoacetic acid should be stored in a cool, dry, well - ventilated area, away from heat and ignition sources. It should be kept in a tightly - sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Store it separately from incompatible substances such as bases, oxidizing agents, and reducing agents to prevent dangerous reactions.
Shipping Bromoacetic acid is a hazardous chemical. It should be shipped in well - sealed, corrosion - resistant containers. Follow all relevant regulations, like using proper labeling for its toxic and corrosive nature, and ensure safe transportation.
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General Information
Frequently Asked Questions
What are the main uses of Bromoacetic Acids?
Bromoacetic acid is also an organic compound. It has a wide range of uses and is important in various fields.
Bear the brunt, and bromoacetic acid is often used as a raw material in the field of pharmaceutical chemistry. Due to the chemical properties of bromoacetic acid, it can participate in the synthesis of various drugs and help create new drugs, which is essential for the development of medicine. For example, in the synthesis of some antibacterial and anti-inflammatory drugs, bromoacetic acid can be a key intermediate. Through a series of delicate chemical reactions, bromoacetic acid can build the core structure of the drug, thereby giving the drug specific pharmacological activity to heal patients.
Furthermore, the manufacture of pesticides also relies on bromoacetic acid. It can be used as an important starting material for the synthesis of many efficient pesticides. In modern agriculture, pesticides are indispensable in order to protect crops from diseases and pests. Pesticides made of bromoacetic acid may have high-efficiency insecticidal and grass-suppressing effects, and can precisely act on the physiological processes of pests, ensure the robust growth of crops, and maintain the stable output of agriculture.
In the field of organic synthetic chemistry, bromoacetic acid is also a commonly used reagent. Because its molecular structure contains active bromine atoms and carboxyl groups, it can trigger rich chemical reactions, such as nucleophilic substitution, esterification, etc. Chemists can use this to construct complex and diverse organic molecular structures, expand the boundaries of organic synthesis, and lay the foundation for the development of materials science, fine chemistry and other related disciplines. For example, when synthesizing polymer materials with special properties, bromoacetic acid may participate in the chain growth reaction of polymers and regulate the properties and structure of materials.
In addition, bromoacetic acid also has a place in the dye industry. It can use it to participate in the reaction of dye synthesis, change the molecular structure of dyes, and then affect the color, light, fastness and other key properties of dyes, so that the dyes can meet the needs of different fabric dyeing, enrich the category of dyes, and add color to the textile printing and dyeing industry.
What are the Physical Properties of Bromoacetic Acids?
Bromoacetic acid is a kind of organic compound. It has all kinds of physical properties, which are described in detail by you today.
Bromoacetic acid is white and crystalline at room temperature, and it is pure and delicate in texture. Its smell is quite pungent and uncomfortable, but it has a certain irritation.
The melting point is about fifty to fifty-two degrees Celsius. This temperature range makes bromoacetic acid easy to melt from solid to liquid in a slightly warmer environment. Its boiling point is about 208 degrees Celsius. When the temperature reaches this point, bromoacetic acid changes from liquid to gas and rises into the air. < Br >
Bromoacetic acid is easily soluble in water. This is because of the characteristics of its molecular structure. It interacts with water molecules to form a uniform and stable solution. And in many organic solvents, it also has good solubility, such as ethanol and ether, which can be soluble with it. This characteristic makes it widely used in organic synthesis and other fields.
Furthermore, the density of bromoacetic acid is heavier than that of water, and it will sink to the bottom when placed in water. Its vapor density is also greater than that of air, so it is easy to accumulate in the lower part in a relatively closed space.
These are the physical properties of bromoacetic acid. In the chemical industry, medicine and many other industries, it is essential to be familiar with its properties.
What to Consider When Storage Bromoacetic Acids
Bromoacetic acid is a toxic and corrosive chemical. When storing, be sure to pay attention to many key matters.
First storage environment. It should be placed in a cool and ventilated warehouse. Bromoacetic acid is easily decomposed due to heat. If it is exposed to a high temperature environment, it may decompose to produce harmful gases, and high temperature may also increase its volatilization rate and increase safety risks. This cool and ventilated place can maintain the temperature and humidity within a suitable range, reducing the possibility of its properties changing due to environmental factors.
Times and packaging is sealed. Make sure the packaging is complete and well sealed. Bromoacetic acid is highly corrosive. If the packaging is damaged, it can corrode surrounding objects and evaporate into the air after leakage, which will cause serious harm to personnel and the environment. Sealed packaging can effectively prevent it from coming into contact with outside air, moisture, etc., and prevent chemical reactions and deterioration.
Furthermore, it should be stored in isolation. It should not be stored in the same way as oxidants and bases. Bromoacetic acid meets the oxidant, or triggers a violent redox reaction, which is at risk of combustion and explosion; when it comes into contact with alkalis, it is easy to neutralize and change its chemical properties, and may also generate a lot of heat, resulting in danger. Therefore, it should be placed separately from such substances to maintain a safe distance.
In addition, the storage area should be equipped with suitable containment and handling materials. In the event of leakage, bromoacetic acid can be collected and treated in time to avoid the diffusion of bromoacetic acid and reduce pollution to the environment and harm to personnel. And there must be obvious warning signs, so that the contact person can clearly understand the danger, be vigilant, and operate cautiously. In this way, the safety of bromoacetic acid storage can be ensured and accidents can be avoided.
What are the dangers of Bromoacetic Acids to the human body?
Bromoacetic acid is harmful to the human body. It is highly corrosive and can cause severe pain when it touches the skin. Erythema and blisters appear quickly. The injury is deep and difficult to heal. If it accidentally touches a large number, or involves deep tissues, leaving scars and affecting limb activities. If it enters the eye, the damage is particularly severe. It can cause eye pain, tears, blurred vision, severe damage to the cornea and conjunctiva, and even blindness.
Smell it, the vapor of bromoacetic acid is extremely irritating. When it enters the respiratory tract, it can cause cough, sore throat, chest tightness, and shortness of breath. If inhaled in large amounts, it can cause chemical pneumonia and pulmonary edema, which is life-threatening.
If ingested inadvertently, it can burn the oral cavity, esophagus, and gastric mucosa, causing nausea, vomiting, abdominal pain, diarrhea, and even gastrointestinal bleeding and perforation, causing systemic poisoning symptoms such as headache, dizziness, fatigue, and convulsions. In severe cases, it can cause coma and organ failure.
Long-term exposure to bromoacetic acid-containing environments may also be potentially harmful. Or affect the human body's immune system, reduce immunity, and be prone to diseases. And it may be teratogenic, carcinogenic, and mutagenic. Although this aspect needs to be studied in depth, the latent risk should not be underestimated. Everyone should be careful. When working, they must follow safety procedures and take good protection to avoid being harmed by it.
What are the production methods of Bromoacetic Acid?
The preparation method of bromoacetic acid (Bromoacetic Acid) has been known in ancient times, and there are many methods. Today, I will describe it in detail.
First, acetic acid is used as the starting material and obtained by bromination reaction. The acetic acid is placed in a reactor, and an appropriate amount of catalyst is added, such as red phosphorus or phosphorus tribromide. Then bromine is slowly introduced, and the two react at a suitable temperature and pressure. Bromine reacts with the methyl group in acetic acid to form bromoacetic acid. During this reaction process, it is necessary to precisely control the reaction conditions, such as temperature and bromine entry rate. If the temperature is too high, it is easy to cause side reactions to occur and form polybrominates; if the temperature is too low, the reaction rate is slow and takes a long time. The raw materials of this method are easy to obtain and the operation is relatively simple, but the purity of the product may need to be further improved.
Second, bromoacetic acid is prepared by halogen exchange reaction using chloroacetic acid as raw material. Chloroacetic acid and brominating agents, such as sodium bromide or potassium bromide, are placed together in a specific solvent, and suitable catalysts, such as quaternary ammonium salts, are added. Under the condition of heating and reflux, chlorine atoms and bromine atoms are exchanged to form bromoacetic acid. The advantage of this method is that the reaction conditions are relatively mild and the product purity is high. However, it is necessary to pay attention to the selection of suitable solvents and catalysts to improve the reaction efficiency and properly handle the by-products of halide salts produced during the reaction.
Third, with hydroxyacetic acid as the starting material, first mix hydroxyacetic acid with hydrobromic acid, and under the action of a certain temperature and catalyst, the hydroxyl group is replaced by bromine atoms to obtain bromoacetic acid. This process requires strict control of the reaction temperature and reaction time to avoid overreaction or incomplete reaction. This method can directly utilize the activity of hydroxyacetic acid and has certain innovation. However, the purity of the raw material hydroxyacetic acid is higher, and hydrobromic acid is corrosive, so careful protection is required during operation.
These are all common preparation methods for bromoacetic acid, each with its own advantages and disadvantages. In actual production, the best should be selected according to the specific situation.