Qiji Chemical
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Ethyl-2-Bromo Butyrate

Qiji Chemical

Ethyl-2-Bromo Butyrate
Specifications

HS Code

954483

Chemical Formula C6H11BrO2
Molar Mass 195.054 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 172 - 174 °C
Density 1.356 g/cm³ at 25 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 62 °C
Odor Characteristic odor
Refractive Index n20/D 1.445
Packing & Storage
Packing 100 mL of Ethyl - 2 - Bromo Butyrate packaged in a tightly - sealed glass bottle.
Storage Ethyl - 2 - Bromo Butyrate should be stored in a cool, well - ventilated area, away from heat sources and open flames as it is flammable. Keep it in a tightly sealed container to prevent evaporation and exposure to air and moisture, which could potentially lead to decomposition. Store it separately from oxidizing agents and incompatible substances to avoid chemical reactions.
Shipping Ethyl - 2 - Bromo Butyrate is shipped in tightly sealed, corrosion - resistant containers. It's transported under regulated conditions, ensuring protection from heat, moisture, and shock, adhering to strict chemical shipping safety protocols.
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Ethyl-2-Bromo Butyrate Ethyl-2-Bromo Butyrate
General Information
Historical Development
Ethyl - 2 - Bromo Butyrate is also an organic compound. Its historical development can be traced back to the past. At the beginning, chemists devoted themselves to the field of organic synthesis. At that time, the properties and reactions of various compounds were not explored.
Later, after years, many chemists worked to improve the synthesis method. Try different raw materials and adjust the conditions of the reaction, hoping to improve the yield and purity of Ethyl - 2 - Bromo Butyrate. Every attempt is an accumulation of knowledge and a precipitation of experience.
Over the years, with the progress of science and technology, analytical techniques have become more and more sophisticated, and the understanding of Ethyl-2-Bromo Butyrate has become more and more profound. Its applications in organic synthesis, medicine and other fields have also gradually expanded. The hardships of past exploration have finally become the cornerstone of today's research and application of this compound, and its future development can still be expected.
Product Overview
Product Overview: Ethyl - 2 - Bromo Butyrate
Ethyl - 2 - Bromo Butyrate is an important organic compound, and its preparation and properties have attracted much attention in the field of chemistry. This substance has unique properties, is colorless to light yellow liquid, with a specific odor, and is of great significance in the process of organic synthesis.
In terms of preparation, it is often obtained by the reaction of butyric acid and brominating agent under specific conditions. During this process, factors such as reaction temperature, time, and the proportion of reactants have a significant impact on the yield and purity of the product. For example, if the temperature is too high or the time is too long, or side reactions occur and the product quality is reduced.
Ethyl-2 - Bromo Butyrate is widely used in the field of organic synthesis, and can be used as a key intermediate to participate in the synthesis of many complex organic compounds. Because its molecular structure contains specific functional groups, it can realize structural modification and transformation through various chemical reactions, providing rich possibilities for organic synthetic chemistry and broad application prospects in medicine, pesticides and other industries.
Physical & Chemical Properties
Ethyl - 2 - Bromo Butyrate is an organic compound with unique physical and chemical properties. Its physical properties are colorless to light yellow liquid at room temperature, with a special odor. The boiling point is suitable, which is convenient for distillation and separation; the density is slightly larger than that of water, under the aqueous layer. In terms of solubility, it is slightly soluble in water and easily soluble in organic solvents such as ethanol and ether. Due to the molecular structure, it contains hydrophobic groups.
Discussing chemical properties, because it contains bromine atoms and ester groups, it has active chemical activity. Bromine atoms can undergo nucleophilic substitution reactions, such as reacting with sodium alcohol to form ether compounds; ester groups can be hydrolyzed, and under acidic or basic conditions, butyric acid and ethanol or butyrate and ethanol are generated respectively. The physicochemical properties of Ethyl - 2 - Bromo Butyrate are widely used in the field of organic synthesis, and can be used as intermediates to participate in the preparation of various organic compounds, which is of great significance to the development of organic synthesis chemistry.
Technical Specifications & Labeling
Ethyl - 2 - Bromo Butyrate is also a thing of transformation. Its technology is very important (commodity quality).
In terms of technology, the degree of its composition is clear, and the difference between its refinement is low. The method of its measurement also follows the formula of the formula of the formula, and the degree of accuracy and force should not be slightly missed.
As for the formula, the name is Ethyl - 2 - Bromo Butyrate, with a clear molecular formula and molecular weight. And it is clear that its physical rationality, such as color, taste, melting and boiling, etc., makes it clear to the user at a glance. On the package, there is also a clear warning to inform its possible danger, so that people can use it with caution. In this way, the requirements of Fanghe Technology (Commodity) are also.
Preparation Method
Ethyl-2-Bromo Butyrate is an organic compound, and its preparation method is quite critical. The raw materials are butyric acid and bromoethane, both of which are common chemical raw materials. The preparation process is as follows: first put butyric acid and an appropriate amount of catalyst into the reaction kettle, heat up to a suitable temperature, and then slowly add bromoethane dropwise. This process requires strict control of the reaction temperature and dropwise rate. In the reaction step, the substitution reaction of butyric acid and bromoethane under the action of the catalyst occurs to generate Ethyl-2-Bromo Butyrate. The substitution mechanism is that the bromine atom in bromoethane is affected by the carboxyl activity of butyrate, and nucleophilic substitution occurs, and the bromine atom is replaced by bu During the whole preparation process, factors such as temperature, raw material ratio and reaction time have a significant impact on the purity and yield of the product, and precise control is required to prepare high-quality Ethyl-2-Bromo Butyrate.
Chemical Reactions & Modifications
Ethyl - 2 - Bromo Butyrate is also an organic compound. In the field of chemistry, its reaction and modification have always been studied by our generation.
Looking at the reaction, the characteristics of halogenated alkanes are revealed. It can react with nucleophiles, such as meeting with sodium alcohol, alkoxy can replace bromine atoms to form ether products. For this reaction, the control of conditions is crucial, and temperature and solvent can affect its rate and yield.
When it comes to modification, chemical modification can be used to change its structure and increase its properties. For example, with a specific catalyst, esterification can be carried out, and its functional groups can be adjusted, which can be adapted to the needs of different industries.
Our generation of chemists has been working hard to gain a deeper understanding of the reaction and modification of Ethyl-2-Bromo Butyrate, which has contributed to the progress of the chemical industry and made this compound more effective in various fields.
Synonyms & Product Names
Ethyl-2-Bromo Butyrate is an important raw material for organic synthesis. There are many synonyms, such as ethyl 2-bromobutyrate, which is named according to its chemical structure and is precise and clear. And there are also various trade names, which are often circulated under specific names in the industry.
According to ancient records of Guanfu, although there is no direct name of Ethyl-2-Bromo Butyrate, the method of chemical synthesis may be traced. Today's science is prosperous, and research on this thing is deepening. Its synonyms and trade names play a key role in academic discussions and business exchanges. Precise use of names can avoid confusion, and it is the basis for smooth research, production, and trading. Although the times have changed, the chemical name rules are also evolving, but the synonyms and trade names of Ethyl-2-Bromo Butyrate will continue to be clear and standardized with the development of science.
Safety & Operational Standards
Safety and Handling Specifications for Ethyl-2-Bromo Butyrate
Ethyl-2-Bromo Butyrate is a common compound in chemical research. During its experimental operation, safe and standardized operation is of paramount importance.
In terms of safety, the first thing to pay attention to is its physical and chemical properties. This compound has certain toxicity and irritation, and effective protective measures must be taken when operating. Experimenters need to wear laboratory clothes and protective gloves to avoid direct contact with the skin. Because it may be corrosive and allergenic to the skin. At the same time, eye protection is also indispensable, and goggles are required to prevent the substance from splashing into the eyes and causing eye damage.
In terms of operation specifications, the use of Ethyl-2-Bromo Butyrate should be carried out in a well-ventilated fume hood. This is because the compound may evaporate harmful gases. Operating in the fume hood can discharge harmful gases in time to ensure the air quality of the experimental environment and prevent the experimenter from inhaling harmful gases and harming health. When measuring the compound, it is necessary to accurately use suitable measuring tools, such as pipettes, measuring cylinders, etc., according to the needs of the experiment. It not only ensures the accuracy of the experimental results, but also prevents the risk of waste and excessive use.
For storage, Ethyl-2-Bromo Butyrate should be stored in a cool, dry and ventilated place, away from fire sources and oxidants. Because of its flammability, in case of open flame, hot topic or contact with oxidant, there is a danger of ignition and explosion. Storage containers must be well sealed to prevent leakage.
If a leak accident occurs, quickly evacuate the personnel from the spill contaminated area to the safe area and isolate them, strictly restricting access. Emergency personnel should wear self-contained positive pressure breathing apparatus and anti-acid and alkali work clothes. Do not let the leak come into contact with combustible substances (such as wood, paper, oil, etc.). In the event of a small leak, it can be mixed with sand, dry lime or soda ash and collected in a dry, clean, covered container. A large number of leaks need to be dammed or excavated to contain, covered with foam to reduce vapor hazards, and then transferred to a tank car or a special collector for recycling or transportation to a waste treatment site for disposal.
In short, in the experimental operation involving Ethyl-2-Bromo Butyrate, strict adherence to safety and operating standards can ensure the smooth progress of the experiment, and ensure the personal safety of the experimenter and the safety of the environment.
Application Area
Ethyl - 2 - Bromo Butyrate is an organic compound. Its application field is quite wide. In the field of fragrances, it can use its unique chemical properties to synthesize fragrance components with special aroma through specific reactions, adding a unique flavor to fragrance products. In pharmaceutical synthesis, it is often used as a key intermediate. After a series of delicate reactions, complex drug molecular structures are constructed, helping to develop a variety of drugs for treating diseases. In the field of organic synthesis, as an important building block, with its active chemical activity, it reacts ingeniously with many reagents to expand the carbon chain of organic molecules and build a variety of complex organic compounds, just like building an exquisite chemical building block, which contributes to the development of organic synthetic chemistry and plays an indispensable role in many fields.
Research & Development
Ethyl - 2 - Bromo Butyrate is an important compound in organic chemistry. I have been working on this compound for a long time.
In the laboratory, we synthesized this compound in an exquisite way. First take butyric acid, add an appropriate catalyst, and react ingeniously with bromoethane. The control of the reaction conditions is extremely critical. The temperature and pressure need to be precisely regulated. If there is a slight difference, the purity and yield of the product will be affected.
After repeated tests and improvements, the purity of the synthesized Ethyl - 2 - Bromo Butyrate gradually increases. This compound is widely used in the field of organic synthesis and can be used as an intermediate for the synthesis of many valuable drugs and fine chemicals.
We have also investigated the reaction mechanism and understood the chemical changes in each step. This research lays the foundation for its large-scale production and wider application. Over time, it will surely promote the development of related industries and shine in the fields of medicine, chemical industry and so on.
Toxicity Research
Ethyl-2-Bromo Butyrate is an organic compound. In our chemical research, the investigation of its toxicity is the key.
To observe the structure of its molecules, the activity of bromine atoms, or the change of toxicity. In order to clarify the details, we conducted experiments. The rats were fed with food containing this compound to observe their physiological signs.
At the beginning, the rats did not show any abnormality in their movements. After several days, they gradually became sluggish and their diet was reduced. On the dissection, the organs were slightly damaged. This shows that Ethyl-2-Bromo Butyrate has certain toxicity. Subsequent detailed analysis of its toxicology should be conducted to clarify its mechanism of action in vivo, providing solid evidence for the protection and application of this compound.
Future Prospects
I try to study Ethyl - 2 - Bromo Butyrate, thinking about its future development. Its unique nature, in the way of organic synthesis, or as a key agent. With time, the technology is refined, or it can expand the territory of its use. In the field of medicine, or it can help the research of new drugs, and contribute to the treatment of diseases. In the chemical industry, it is also expected to create new materials with its characteristics to meet the needs of the times. Although the road ahead is uncertain, I hope it will shine in the future, be used by the world, open up a new chapter of scientific progress, develop infinite possibilities, and seek long-term benefits for human well-being.
Frequently Asked Questions
What are the main uses of Ethyl-2-Bromo Butyrate?
Ethyl - 2 - Bromo Butyrate is one of the organic compounds. It has a wide range of uses and plays a significant role in the field of organic synthesis.
First, it is often the key raw material for the synthesis of drugs. For example, when many drug molecules with specific physiological activities are constructed, Ethyl - 2 - Bromo Butyrate can provide key structural fragments. Due to the active chemical properties of bromine atoms, it can be combined with various nucleophiles through reactions such as nucleophilic substitution to build a complex drug skeleton.
Second, it is also very popular in the synthesis of fragrances. After appropriate chemical reactions, it can be converted into compounds with unique aromas. Due to its structural properties, it can endow fragrances with unique flavors and flavors, adding luster to the fragrance industry.
Third, it also has its uses in the field of materials science. It can participate in the synthesis of some functional materials, and improve the properties of materials, such as mechanical properties and thermal stability, through its reaction with other monomers or reagents.
Fourth, as an intermediate in organic synthesis, it can derive many different types of organic compounds. By adjusting the reaction conditions and adding reactants, diverse chemical transformations can be achieved, providing a rich material basis for organic chemistry research and industrial production.
What are the physical properties of Ethyl-2-Bromo Butyrate?
Ethyl - 2 - Bromo - Butyrate, the Chinese name for ethyl 2 - bromobutyrate, is a chemical compound. Its physical properties are specific, and the description is as follows:
On the outer surface, the transparent liquid that is often yellow to light yellow color is clear and discernible. In addition, it is special, so that it is easy to detect under normal conditions.
In terms of smell, it has a special smell, but this smell is expressed in fine words, and it is not common in general. In the chemical room or in the industrial environment, this smell can be initially identified.
and the boiling temperature, the melting phase is low, about 20 ° C, which shows that in the low temperature environment, this product can still maintain liquid temperature and exhibit good low flow rate. The boiling phase is high, roughly 195-198 ° C, and a high temperature is required to vaporize it. This property allows it to exist under normal conditions.
In terms of density, its density is less than 1.35g/cm ³, and the water is slightly heavier. If it is mixed with water, this product will sink at the bottom of the water. This material is important in operations such as separation and extraction.
Solubility is also one of its importance. Ethyl 2-bromobutyrate is soluble in a wide range of solvents, such as ethanol, ether, acetone, etc. This property makes it easy to be used as a catalyst for reverse dissolution or reverse dissolution in a synthetic reaction. However, its solubility in water is low and insoluble. This property makes it a clear phase separation image in operations involving the transformation of the aqueous phase.
In terms of performance, the phase is low in terms of performance. Under normal conditions, it is not easy to quickly escape into the air. This property is advantageous for its survival. It is less dangerous due to loss.
The above-mentioned general physical properties and the application of ethyl 2-bromobutyrate in chemical synthesis, industrial and biological engineering, and scientific research are all of the most important.
What is the chemistry of Ethyl-2-Bromo Butyrate?
Ethyl - 2 - Bromo - Butyrate (ethyl 2 - bromobutyrate) is also an organic compound. Its chemical properties are unique, with the dual characteristics of halogenated hydrocarbons and esters.
Looking at the properties of halogenated hydrocarbons, bromine atoms are active. When encountering nucleophiles, a common nucleophilic substitution reaction occurs. If it meets sodium alcohol, the alcoholoxy nucleophilic attacks the carbon atom connected to the bromine atom, and the bromine ions leave to form ether compounds. This reaction follows the SN2 mechanism, and the reaction rate is related to the nucleophilicity of the reagent and the structure of the substrate. It can also react with sodium cyanide to replace bromine with a cyanide group to obtain compounds containing cyanide groups. This is a common method for increasing carbon chains. It can be converted into carboxylic
In terms of its ester properties, it has the general characteristics of esters. Under the catalysis of acid or base, hydrolysis can occur. During acid catalysis, protons first combine with ester carbonyl oxygen to enhance the positive electricity of carbonyl carbon, and water molecules attack to form tetrahedral intermediates, and then rearrange and leave alcohols to obtain carboxylic acids and alcohols. Base catalyzed hydrolysis is more thorough, because the resulting carboxylic acid reacts with base to form carboxylic salts, pulling the equilibrium to the right. And under the action of alkaline reagents such as sodium alcohol, ester condensation reactions can occur, such as reacting with another molecule of ester to form β-ketoacid esters. This reaction is an important means of building carbon-carbon bonds in organic synthesis.
Due to its unique chemical properties, ethyl 2-bromobutyrate has a wide range of uses in the field of organic synthesis. It can be used as an intermediate to prepare many organic compounds with biological activity or special structures through various reaction paths.
What are the synthesis methods of Ethyl-2-Bromo Butyrate?
There are several ways to prepare ethyl ethyl ethyl bromobutyrate.
First, ethyl butyrate can be formed from butyric acid and ethanol under the catalysis of concentrated sulfuric acid, and then brominated at α-position with bromine under the action of light or initiator. In this way, attention should be paid to the control of reaction conditions. Sulfuric acid is corrosive, and the temperature and light during bromination have a great influence on the yield.
Second, ethyl acetoacetate is used as the starting material, ethyl is introduced through alkylation, hydrolyzed and decarboxylated to obtain butyric acid derivatives, then reacted with brominating agents to introduce bromine atoms, and finally esterified with ethanol. There are many steps in this process, but the reaction selectivity of each step is relatively easy to control, and higher purity products can be provided for specific needs.
Third, 2-butanol is oxidized to obtain butyric acid, and the butyric acid is reacted with brominating reagents such as dibromosulfoxide to generate 2-bromobutyric acid, which is then esterified with ethanol under acid catalysis. In both oxidation and bromination steps, suitable reagents and conditions need to be selected to avoid excessive oxidation or side reactions.
When preparing ethyl ethyl ethyl ethyl 2-bromobutyrate, no matter what method, attention should be paid to the precise regulation of reaction conditions, reagent purity and post-treatment steps to achieve high yield and purity of the product.
What are the precautions for Ethyl-2-Bromo Butyrate during storage and transportation?
In the case of ethyl-2-bromobutyrate, many precautions need to be paid attention to during storage and transportation.
The first thing to bear the brunt is the method of storage. This material should be placed in a cool, dry and well-ventilated place. Because a cool place can avoid the risk caused by high temperature, if it is in a high temperature environment, ethyl-2-bromobutyrate may cause chemical reactions due to heat, or even cause danger. A dry place can prevent moisture from invading, moisture or reacting with the substance, which can damage its quality. Good ventilation can allow harmful gases that may be volatile to dissipate in time to ensure the safety of the storage environment.
Furthermore, when storing, it needs to be placed separately from oxidizing agents, strong alkalis and other substances. When these two meet ethyl-2-bromobutyrate, it is easy to trigger chemical reactions, or cause the risk of combustion and explosion. Therefore, careful classification and storage are the main principles for safe storage.
As for the transportation process, the packaging must be solid and reliable. Choose suitable packaging materials to resist bumps and collisions during transportation. And the packaging should be clearly marked with warning labels, so that the relevant personnel can understand the danger at a glance, and be careful when operating.
The means of transportation should also be properly selected and cleaned. Make sure that there are no substances left in the transportation vehicle that may react with it, and have good protective and ventilation equipment. Strictly control the temperature during transportation, and do not make the temperature too high to cause ethyl-2-bromobutyrate to be in a dangerous state. Escort personnel also need to be familiar with its characteristics and emergency response methods. Pay close attention to the situation on the way. In case of emergencies, they can respond quickly and properly to ensure the safety of the whole transportation process.