Qiji Chemical
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1,4-Dibromobenzene

Qiji Chemical

1,4-Dibromobenzene
Specifications

HS Code

150011

Name 1,4 - Dibromobenzene
Molecular Formula C6H4Br2
Molar Mass 235.90 g/mol
Appearance White to light - yellow solid
Odor Characteristic odor
Density 2.20 g/cm³
Melting Point 87 - 89 °C
Boiling Point 219 - 221 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in ethanol, ether, benzene
Vapor Pressure Low vapor pressure
Flash Point 110 °C
Packing & Storage
Packing 1,4 - Dibromobenzene packaged in 1 - kg bottles for safe storage and handling.
Storage 1,4 - Dibromobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in tightly - sealed containers to prevent leakage and exposure to air and moisture. Label the storage containers clearly to avoid misidentification. Store it separately from incompatible substances to ensure safety.
Shipping 1,4 - Dibromobenzene is shipped in tightly sealed containers, often within outer packaging for protection. It's transported by appropriate means following chemical shipping regulations to prevent spills and ensure safety during transit.
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1,4-Dibromobenzene 1,4-Dibromobenzene
General Information
Historical Development
1,4-Dibromobenzene is an organic compound. It has been explored in the field of chemistry in the past. At first, it was difficult to make this product, and the yield was not high. However, as time went by, scholars studied it diligently, and the method of making it became more and more exquisite. In the past, 1,4-dibromobenzene was obtained by a halogenation reaction based on benzene. However, the reaction conditions were harsh, and impurities were easy to grow. After repeated study, the method was improved, suitable catalysts were selected, and various conditions such as temperature and pressure were controlled, so that the reaction was more controllable and the yield was greatly improved. Nowadays, 1,4-dibromobenzene is widely used in medicine, materials, and many other fields. Its preparation process has also been continuously refined with the advancement of science and technology. It has been created through the difficulties of the past and has been produced to this day. It has witnessed the evolution of chemical technology and has also added a lot of help to the development of industry and scientific research.
Product Overview
1,4-Dibromobenzene is an organic compound. It is a colorless to pale yellow needle-like crystal with a special odor.
This compound has a wide range of uses in the chemical industry. In organic synthesis, it is often used as a key intermediate. With its structural properties, it can be derived from a variety of organic materials with different functions through many chemical reactions.
1,4-Dibromobenzene is prepared in the laboratory, mostly using benzene as the starting material and obtained by bromination reaction. During the reaction, attention should be paid to the control of reaction conditions, such as temperature and catalyst dosage, which will affect the purity and yield of the product.
The physical properties of 1,4-dibromobenzene are stable, with a melting point of 87-89 ° C and a boiling point of 219 ° C. It is insoluble in water, but easily soluble in organic solvents such as ethanol and ether.
When using 1,4-dibromobenzene, caution should also be taken. Due to its certain toxicity, relevant safety procedures should be followed during operation to avoid harm to human body and the environment.
Physical & Chemical Properties
1,4-Dibromobenzene is an organic compound. Its color is crystal clear, like a fine powder, and it is solid at room temperature. It has a specific degree of melting and boiling, with a melting point of about 14 to 116 degrees Celsius and a boiling point of 220 to 222 degrees Celsius. This substance is slightly soluble in water, but it is easily soluble in organic solvents such as ethanol and ether.
In terms of its chemical properties, the dibromine atom on the benzene ring makes it quite active and can involve many chemical reactions. Such as the reaction of nucleophilic substitution, the bromine atomic energy is replaced by other groups, and various products are derived. And because it contains bromine, when burning or generating halogenated hydrogen gases such as hydrogen bromide, it is necessary to pay attention to safety when using it.
Technical Specifications & Labeling
1,4-Dibromobenzene is a key raw material for organic synthesis. Its preparation process depends on specific technical specifications and standards (product parameters).
First take an appropriate amount of benzene, put it in a reactor, control the temperature in a suitable range, slowly drop in liquid bromine, and add an appropriate amount of catalyst, such as iron filings. This reaction is intense, and careful attention should be paid to temperature changes to prevent overheating.
After the reaction is completed, neutralize and wash with water to remove impurities. Distillation is performed to collect fractions in a specific boiling point range to obtain crude 1,4-dibromobenzene.
After recrystallization, purify the product with a suitable solvent, such as ethanol. The recrystallization process requires precise temperature control and stirring to ensure the crystallization effect.
Its product index, the appearance should be white crystal, the melting point should be 138-141 ℃, and the purity should not be less than 99%. In this way, high-quality 1,4-dibromobenzene products can be obtained to meet the needs of various fields.
Preparation Method
The preparation of 1,4-dibromobenzene is crucial to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are commonly used benzene and bromine. Iron filings or iron tribromide are used as catalysts, and the two react in a specific container.
At the beginning of the reaction, the container is cleaned first to ensure that there are no impurities. Pour benzene in slowly, add a catalyst, and stir well. Then drop bromine in proportion and rate. Because the reaction is exothermic, the temperature needs to be controlled to prevent side reactions from occurring.
During the reaction of benzene and bromine under the action of the catalyst, bromine atoms replace hydrogen atoms on the benzene ring to obtain 1,4-dibromobenzene. After the reaction is completed, the product is purified by distillation, extraction and other methods to remove unreacted raw materials, by-products and catalyst residues. In this way, pure 1,4-dibromobenzene can be obtained for subsequent chemical use.
Chemical Reactions & Modifications
In the past, 1,4-dibromobenzene was often obtained by the method of benzene and bromination. However, it was difficult to solve this problem, and there were many side effects.
The current situation is the way to think about it. Or new catalysis, in order to promote the reaction speed and increase the reaction rate; or change the environment, so that there are fewer side effects.
If a new type of catalysis is used, it can reduce energy and make bromination easy. And it is soluble, anti-reaction, and controllable.
There is also a color concept to change the reverse route, less pollution, and meet the needs of. This is the exploration of the reverse modification of 1,4-dibromobenzene, hoping to obtain a good method to improve the chemical industry.
Synonyms & Product Names
1,4-Dibromobenzene, the genus of chemical substances. It has a wide range of uses in the field of chemical industry. It is often used as a key raw material in the preparation of various chemicals.
This substance is also known as more, which are all synonyms. Or p-dibromobenzene, which is derived from the relative position of the bromine atom in its molecular structure. There are also those who call it in the name of commercial use. In the market, the names of various merchants may be different, but they all refer to this 1,4-dibromobenzene.
This substance has unique properties and often has specific manifestations in reactions, which are valued by chemists. Through precise processing, high-purity 1,4-dibromobenzene can be obtained to meet the needs of all parties. Whether it is academic research or industrial production, its synonyms and trade names are different, but they are all essential for advancing the field of chemistry.
Safety & Operational Standards
Safety and Operation Specifications for 1,4-Dibromobenzene
The man of 1,4-dibromobenzene is a common chemical in chemical research. To make good use of this substance, it is necessary to clarify its safety and operation specifications in order to ensure the smoothness of the experiment and protect the health of the human body.
In terms of safety, 1,4-dibromobenzene has certain toxicity. If its vapor is inhaled by the human body or penetrated through skin contact, it can cause harm. Therefore, when operating, it must be in a well-ventilated place to prevent vapor accumulation. If conditions permit, when equipped with a fume hood to ensure the safety of the operating environment. And when operating, it is appropriate to wear protective clothing, such as laboratory clothes, gloves, etc., to prevent skin contact with it. If you accidentally touch it, you should immediately rinse it with a large amount of water and seek medical attention as appropriate.
Furthermore, 1,4-dibromobenzene is flammable. In the place of storage and use, keep away from fire and heat sources, and strictly prohibit fireworks. And its storage place should be dry and cool to prevent it from changing its properties due to heat and moisture and causing danger.
As for the operating instructions, when taking 1,4-dibromobenzene, the action should be gentle and precise. Because of its toxicity, it should not be touched directly by hand, and should be taken with suitable tools, such as spoons, pipettes, etc. After use, the remaining products should not be discarded at will, and should be properly disposed of in accordance with regulations to prevent pollution of the environment.
During the experiment, if the reaction of 1,4-dibromobenzene is involved, it must be planned in detail. The reaction conditions, such as temperature, pressure, and the proportion of reactants, should be precisely controlled. And during the experiment, when paying close attention to the reaction process, if there is any abnormality, such as sudden temperature change, odor, etc., the operation should be stopped immediately to find out the cause and ensure safety.
In conclusion, although 1,4-dibromobenzene has its uses in chemical research, its safety and operating standards must not be ignored. Researchers must treat it strictly in order to ensure safety, exert its effectiveness and achieve the purpose of research.
Application Area
1,4-Dibromobenzene is also a chemical substance. Its application field is quite extensive. In the field of medicine, it is often the key raw material for the synthesis of many drugs, which can help to form special drugs and cure various diseases. In materials science, it is the cornerstone of the preparation of high-performance materials, such as special plastics and fibers, with excellent properties. In the electronics industry, it can be used to manufacture electronic components to make electronic products perform better. These applications rely on the unique chemical properties of 1,4-dibromobenzene. Based on it, researchers continue to study and innovate, expand its application boundaries, and hope to bring more benefits and progress to the world.
Research & Development
In recent years, I have been focusing on chemical substances, focusing on 1,4 - Dibromobenzene. This substance has a wide range of uses and has its uses in the fields of medicine and materials.
I began to explore its synthesis method. At first, according to the traditional method, the yield was not as satisfactory. Then I thought hard, looked up ancient books and modern works, and tried again and again. Adjust the temperature and pressure of the reaction, and replace the catalytic agent. After several years, I finally got an optimized method, and the yield increased significantly.
Both get a good method and consider the road to industrialization. Consider cost and environmental protection. Find cheap and environmentally friendly raw materials, improve equipment, and strive to produce efficient and green.
Looking to the future, Ji 1,4 - Dibromobenzene will show its skills in more new fields. I will also make unremitting efforts to contribute to its development, promote the progress of chemistry, and benefit the world.
Toxicity Research
The recent toxicity study of 1,4-Dibromobenzene is quite important. The use of this substance is becoming more and more widespread, but its toxic effects are not yet fully understood.
We study it carefully to observe its effect on organisms. Take all kinds of creatures as samples and observe their changes after being disturbed by this substance. See it may damage the function of the viscera, or disrupt the order of physiology.
After many tests, it can be seen that 1,4-Dibromobenzene enters the body and easily accumulates in the liver and kidney. Over time, the ability of the liver and kidney is gradually weakened, and the qi and blood are also impaired. And it may disturb the control of the nerves, cause the behavior of the living beings to be abnormal, and the perception is also deviated.
From this point of view, the toxicity of 1,4-Dibromobenzene cannot be underestimated. In the future, its use should be used with caution to minimize the harm and ensure the safety of all living beings and the peace of the environment.
Future Prospects
1,4 - Dibromobenzene is also a product of transformation. Today, this product, its performance is also determined, and it is often an important raw material in the process of general transformation and reaction.
We look forward to it, and its use will be necessary. In the field of materials science, we can assist in the research of new types of materials, so that the sub-device is more delicate and convenient. In the field of research and development, it may be possible to synthesize special effects, saving the world.
And technology is changing with each passing day, and the research method must also be exquisite. In the future, it will be possible to obtain more colorful and efficient solutions, reduce its cost and increase its volume. In this way, 1,4 - Dibromobenzene will be able to expand its color in the future, and promote the progress of many fields. We look forward to the grand future of the future.
Frequently Asked Questions
What are the main uses of 1,4-dibromobenzene?
1,4-Dibromobenzene is an organic compound with a wide range of uses.
In the field of chemical synthesis, this is an important raw material. Through specific chemical reactions, many high-value fine chemicals can be prepared. For example, through substitution reactions, other functional groups can be introduced on the benzene ring, and then organic molecules with special structures can be synthesized for the creation of medicines and pesticides. In the development of many new drugs, 1,4-dibromobenzene is often used as a starting material. Through multi-step reactions, the core skeleton of drug molecules is constructed, which has a profound impact on drug activity and pharmacological properties.
It also contributes to the field of materials science. In the preparation of high-performance polymer materials, 1,4-dibromobenzene can participate in the polymerization reaction as a comonomer. This can regulate the structure and properties of the polymer, such as improving the heat resistance and mechanical properties of the polymer. In the preparation of some special engineering plastics, adding an appropriate amount of 1,4-dibromobenzene can significantly improve the comprehensive properties of the material, making it applicable in high-end fields such as aerospace and electronics.
In addition, in the study of organic synthetic chemistry, 1,4-dibromobenzene is a commonly used model compound. By studying their chemical reaction mechanisms, researchers can gain a deep understanding of the reaction characteristics of aromatic compounds, providing theoretical and practical basis for the development of new organic synthesis methods and strategies, and promoting the development and progress of organic chemistry.
What are the physical properties of 1,4-dibromobenzene?
1% 2C4-dibromobenzene is an organic compound with the following physical properties:
1% 2C4-dibromobenzene is colorless to pale yellow needle-like crystal at room temperature and has a special odor. Its melting point is quite high, about 87-89 ° C, which makes it change from solid to liquid at relatively high temperatures. The boiling point is 219 ° C, indicating that a higher temperature is required to boil it into a gaseous state.
1% 2C4-dibromobenzene has a higher density than water, about 2.205g/cm ³, so it will sink to the bottom when placed in water. It is insoluble in water, but easily soluble in organic solvents such as ethanol, ether, and benzene. The difference in solubility is due to the difference in its molecular structure and the forces between water and organic solvent molecules. At room temperature and pressure, 1% 2C4-dibromobenzene has good stability, but it may cause danger in extreme conditions such as open flames and hot topics. Because of its certain volatility, it will evaporate slowly in the air, and there may be latent risks for volatilization and accumulation in confined spaces. These physical properties are of great significance for the storage, transportation and use of 1% 2C4-dibromobenzene in chemical production, scientific research and experiments.
What are the chemical properties of 1,4-dibromobenzene?
1% 2C4 -dibromobenzene, an organic compound also. Its chemical properties are unique, and are described as follows:
- ** Electrophilic substitution reaction **: The benzene ring is electron-rich and vulnerable to attack by electrophilic reagents. For example, during bromination, because the bromine atom is an ortho-and para-localization group, the new bromine atom multiplies into the ortho-and para-localization of the benzene ring to generate 1,2,4-tribromobenzene. In this reaction, the electrophilic reagent first interacts with the π electron of the benzene ring to form a π complex, and then a carbon atom on the benzene ring forms a sigma bond with the electrophilic reagent to obtain the intermediate carbon positive ion, and then loses
- ** Nucleophilic Substitution Reaction **: Although the nucleophilic substitution of benzene is difficult, the bromine atom in 1% 2C4-dibromobenzene is attached to the benzene ring, causing the electron cloud density of the benzene ring to change. Under strong nucleophilic reagents and suitable conditions, bromine atoms can be replaced by nucleophilic reagents. For example, when reacting with sodium alcohol, bromine atoms can be substituted with alkoxy groups to obtain corresponding ether compounds. In this process, nucleophilic reagents attack carbon atoms connected to bromine, and bromine ions leave. The reaction is completed by SN2 or addition-elimination mechanism.
- ** Reduction Reaction **: 1% 2C4-dibromobenzene can be If metal zinc and acid are used as reducing agents, the bromine atom on the benzene ring can be replaced by hydrogen, and the bromine atom can be gradually removed to obtain the corresponding hydrogenation product. This is through electron transfer, the bromine atom forms a bromine ion and leaves, and the hydrogen atom is added to the benzene ring.
- ** Stability **: Due to the conjugation system of the benzene ring, 1% 2C4-dibromobenzene has certain chemical stability. However, the bromine atom has an electron-absorbing induction effect, which reduces the electron cloud density of the benzene ring, which affects its reactivity to a certain extent. Compared with benzene, some reactions are more likely to occur
In conclusion, the chemical properties of 1% 2C4-dibromobenzene are determined by the benzene ring and the bromine atom. It is widely used in organic synthesis and other fields, and can be used as an intermediate to prepare a variety of organic compounds.
What are the synthesis methods of 1,4-dibromobenzene?
1% 2C4-dibromobenzene is also an organic compound. The synthesis method is about a few ends.
First, benzene is used as the starting material. First, benzene and bromine are electrophilically substituted under the action of catalysts such as iron bromide to obtain bromobenzene. Then, bromobenzene and bromine are reacted under specific reaction conditions, such as suitable temperature, pressure and catalyst environment, and the electrophilic substitution reaction occurs again. After controlling the reaction process and conditions, bromine atoms are mainly introduced into the para-position of bromobenzene to obtain 1% 2C4-dibromobenzene. In this process, the choice and dosage of catalysts, the control of reaction temperature and time are all crucial. If the temperature is too high, or the amount of catalyst is too high, it may lead to side reactions and impure products.
Second, p-aminobenzenesulfonic acid can be used. First, the diazotization reaction converts the amino group into a diazonium salt, and then interacts with cuprous bromide and other reagents, resulting in a Sandmeier reaction. The diazonium group is replaced by a bromine atom to obtain 1% 2C4-dibromobenzene. This path requires attention to the conditions of the diazotization reaction, which is carried out at low temperature and in an acidic environment to prevent the decomposition of diazonium salts. In the Sandmeier reaction, the preparation and use of cuprous bromide must also be appropriate in order to make the reaction proceed smoothly and improve the yield of the product.
Third, p-dichlorobenz In the presence of specific solvents and catalysts, halogen exchange reactions with halides such as potassium bromide can be carried out. After optimizing appropriate reaction conditions, chlorine atoms can be gradually replaced with bromine atoms to obtain 1% 2C4-dibromobenzene. This method requires the selection of suitable solvents to facilitate the reaction, and attention needs to be paid to the kinetic and thermodynamic factors of the reaction to ensure that the reaction proceeds in the direction of generating the target product.
All these synthesis methods have their own advantages and disadvantages. The appropriate method should be carefully selected according to the actual situation, such as the availability of raw materials, cost, and purity requirements of the product.
What are the precautions for storing and transporting 1,4-dibromobenzene?
For 1% 2C4-dibromobenzene, pay attention to everything during storage and transportation.
It is flammable and should be stored in a cool and ventilated storage. The storage temperature should not exceed 30 ° C. Keep away from fire and heat sources. It should be stored separately from oxidants and food chemicals, and should not be mixed. The storage area should be equipped with suitable materials to contain leaks. When handling, it should be handled lightly to prevent damage to packaging and containers.
When transporting, vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. In summer, it should be transported in the morning and evening to prevent sun exposure. Road transportation must be carried according to the specified route, and do not stop in residential areas and densely populated areas. During railway transportation, it is strictly forbidden to slip away. And during transportation, it should be protected from exposure to the sun, rain, and high temperature.
Furthermore, 1% 2C4-dibromobenzene is toxic and irritating. Operators must wear appropriate protective equipment, such as gas masks, chemical safety glasses, anti-toxic infiltration work clothes, rubber gloves, etc., to avoid contact with this chemical. After operation, be sure to clean thoroughly. In case of accidental leakage, personnel from the contaminated area of the leakage should be quickly evacuated to the safe area, and quarantined, and access should be strictly restricted. Emergency personnel must wear self-contained positive pressure breathing apparatus and anti-toxic clothing, and do not directly contact the leakage. In the event of a small leakage, it can be absorbed by sand, vermiculite or other inert materials; in the event of a large leakage, a dike or pit should be built for containment, covered with foam to reduce vapor disasters, and then transferred to a tanker or special collector with an explosion-proof pump for recycling or transportation to a waste treatment site for disposal. In this way, the safety of storage and transportation can be guaranteed.