Qiji Chemical
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4-Chlorotoluene

Qiji Chemical

4-Chlorotoluene
Specifications

HS Code

533297

Chemical Formula C7H7Cl
Molar Mass 126.58 g/mol
Appearance Colorless to yellow - liquid
Odor Aromatic odor
Density 1.07 g/cm³ (at 20 °C)
Boiling Point 162 - 164 °C
Melting Point -35 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in many organic solvents like ethanol, ether
Flash Point 47 °C
Vapor Pressure 1.33 kPa at 39.8 °C
Packing & Storage
Packing 500 - gram bottle of 4 - Chlorotoluene, well - sealed for safe storage.
Storage 4 - Chlorotoluene should be stored in a cool, well - ventilated area, away from heat, sparks, and open flames. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents, acids, and bases. Suitable storage facilities should be designed to avoid environmental contamination in case of spills.
Shipping 4 - Chlorotoluene is shipped in tightly - sealed, corrosion - resistant containers. It must be transported in accordance with hazardous chemical regulations, ensuring proper labeling and safety measures to prevent spills during transit.
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4-Chlorotoluene 4-Chlorotoluene
General Information
Historical Development
4 - Chlorotoluene is also an organic compound. Its historical development can be traced back to the past. Early chemists began to pay attention to this thing when they studied the art of organic synthesis. At that time, technology was not as developed as it is today, and the road of exploration was full of thorns. However, various sages persevered, and after years of trial and error, they gradually understood its properties and production methods. At first, the preparation method was complicated and the yield was low, and it was only made in small quantities in the laboratory. With the passage of time, technological advancements, and technological innovations in the chemical industry, the new method of manufacturing 4-Chlorotoluene has gradually emerged, and the yield has also increased significantly. As a result, it has been able to move from laboratory to industrial production, and is used in many fields, such as medicine, dyes, pesticides, etc., contributing to human life and production. Its historical development is indeed an important chapter in the evolution of chemistry.
Product Overview
4 - Chlorotoluene is an organic compound with a colorless to light yellow liquid and a special odor. This substance is widely used in the industrial field and can be used as an intermediate for medicine, pesticides, dyes, etc.
Its preparation method is often obtained by chlorination of toluene as a raw material. During the reaction process, it is necessary to pay attention to the reaction temperature, catalyst selection and other factors, so as to ensure the purity and yield of the product.
4 - Chlorotoluene is relatively stable in nature. It can still be burned in case of open flame and hot topic. When using, it should also be placed in a cool and ventilated place, away from fire and heat sources to prevent danger. In chemical production and scientific research practice, this compound plays a key role, and its in-depth exploration and rational application are of great significance to the development of many fields.
Physical & Chemical Properties
4 - Chlorotoluene is also an organic compound. Its physical and chemical properties are related to many aspects. Looking at its properties, it is a colorless to light yellow transparent liquid at room temperature, with a special aromatic odor. The boiling point is about 162 ° C, and the melting point is about -35 ° C. The two are related to its state transition temperature. The density is nearly 1.07g/cm ³, which is related to its specific gravity with other substances.
In terms of solubility, it is slightly soluble in water, but can be miscible in organic solvents such as ethanol, ether, and chloroform. This is caused by its molecular polarity and interaction with solvents. In terms of chemical properties, due to the structure of chlorine atoms and benzene rings, chlorine atoms can undergo substitution reactions, and benzene rings can undergo electrophilic substitution reactions, highlighting their unique chemical reactivity and having important uses in the field of organic synthesis.
Technical Specifications & Labeling
4 - Chlorotoluene, organic compounds are also. The technical specifications for its preparation, and the careful selection of the first raw materials. The toluene used must be of high purity and few impurities. The chlorination process, temperature and pressure control are crucial. When accompanied by a suitable catalyst, the reaction can be carried out efficiently.
The identification of its products (commodity parameters) is related to the characterization of quality. Purity is a very high standard, and it can only be praised as excellent. Appearance should be colorless and transparent, and odor-free. Density, boiling point and other parameters have a precise range, which is accurate for measurement.
When preparing, the equipment must be excellent and the operation must be standardized to ensure the stability of product quality. And in the reaction process, real-time monitoring, if there is any deviation, timely adjustment. In this way, we can get high-quality 4-Chlorotoluene products to meet the needs of all parties.
Preparation Method
4-Chlorotoluene is also an organic compound. The preparation method, raw materials and production process, reaction steps and catalytic mechanism are all important.
To prepare 4-chlorotoluene, toluene and chlorine are commonly used as raw materials. In a suitable reactor, iron or iron salt is used as a catalyst, and toluene reacts with chlorine gas. First, heat up to a certain temperature, introduce chlorine gas, chlorine gas is active, and it replaces with the hydrogen atom of the benzene cyclomethyl or para-position of toluene. This is an electrophilic substitution reaction.
The reaction steps are orderly, and chlorine gas is slowly introduced to make the reaction sufficient. Control the temperature, pressure and material ratio to ensure that the reaction proceeds in the direction of generating 4-chlorotoluene. After the reaction is completed, the pure 4-chlorotoluene product is obtained by distillation, extraction and other separation and purification methods. The catalytic mechanism is that the catalyst polarizes the chlorine gas, makes it easier to attack the toluene ring, accelerates the reaction, and improves the yield and selectivity.
Chemical Reactions & Modifications
4-Chlorotoluene is also a chemical substance. Its chemical and reverse modification is important to those who do it. If you want to get the best effect, study the method. For those who are ancient, use a different method. Or modify the anti-chemical components, such as the degree and strength, and observe their transformation. Or easy to use, in order to improve the way.
By a certain method, improve the quality of its molecules, and hope to obtain better performance. In the reaction, observe the image and improve the performance. If the temperature is high and the reaction speed is high, then there may be side effects. If a new one is used, it may increase the efficiency and change the performance.
For those who do not need to explore, seek their own reasons, and change their methods, in order to make the properties of 4-chlorotoluene better, which is beneficial to work and life.
Synonyms & Product Names
4 - Chlorotoluene is also a chemical substance. It is also known as p-chlorotoluene, which is widely used in the industrial field. P-chlorotoluene, with clear color and taste, is an important raw material for organic synthesis.
In past studies, many scholars have studied this substance in detail. It is often a key starting material in the preparation of chemical products. Various derivatives can be prepared through various chemical reactions. The title of p-chlorotoluene also has other names. It may vary slightly according to different regions and industry habits.
However, no matter what it is called, it refers to this substance. Its value in organic synthesis cannot be underestimated. The chemical industry relies on it as a basis to form various fine chemicals. Therefore, the research and application of 4-Chlorotoluene has always been of great importance to the chemical industry and is related to the development of many industries.
Safety & Operational Standards
4-Chlorotoluene safety and operating specifications
4-chlorotoluene is also a chemical substance. It is used in various industrial fields and has a wide range of uses. If you want to use it, you must first clarify its safety and operating specifications, so as to ensure that everything goes smoothly and there is no danger of disaster.
In terms of safety, this substance is dangerous. It is flammable, and it is very easy to burn in case of open flames and hot topics. Therefore, the storage place should be kept away from fire and heat sources, and should be placed in a cool and ventilated place. In the warehouse, there should be no fireworks, and a clear fire ban sign should be set up.
Furthermore, 4-chlorotoluene is also harmful to the human body. Its vapor or mist can irritate the eyes and upper respiratory tract. If inhaled, it can cause cough, shortness of breath in mild cases, or even worse symptoms in severe cases. Skin contact may also cause irritation and discomfort. Therefore, when operating, protective gear is indispensable. Operators wear protective clothing, protective gloves, and appropriate respirators to prevent vapor inhalation.
As for the operating instructions, when taking 4-chlorotoluene, the action should be steady and light, and do not collide with the container to avoid damage and leakage. If you accidentally leak, do not panic. When evacuating unrelated people immediately, cut off the source of fire. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be contained by building embankments or digging holes, and then covered with suitable materials, and then dealt with.
During transportation, it is also necessary to strictly abide by the regulations. Make sure that the container is well sealed, and the transportation vehicle should have corresponding fire and explosion-proof devices. During driving, drivers should not drive tired, and should always pay attention to the condition of the goods.
In short, although 4-chlorotoluene is a useful thing, its safety and operating standards must be observed. In this way, the purpose of production can be achieved, and the safety of people and the environment can be ensured.
Application Area
4 - Chlorotoluene is also an organic compound. Its application field is quite wide. In the field of chemical synthesis, it is often an important raw material. It can be used to produce a variety of fine chemicals, such as pharmaceutical intermediates, to help pharmaceutical research and development and production. In the field of materials, it can participate in the synthesis of high-performance materials and improve material properties.
In the dye industry, 4 - Chlorotoluene also plays an important role. It can provide key structural units for dye synthesis, making dyes rich in color and good performance. And in the preparation of fragrances, it can be used as a raw material to give fragrances a unique aroma.
And in the manufacture of pesticides, it can be the basis for the synthesis of high-efficiency and low-toxicity pesticides, help agricultural pest control, and ensure crop yield and quality. All of this shows that 4 - Chlorotoluene plays a key role in various application fields and promotes the development of related industries.
Research & Development
4-Chlorotoluene is also an organic compound. I have been working hard on it for years. At the beginning, I observed its structure. Chlorine and methyl are coexisting on the benzene ring. This unique structure makes its properties unusual.
The method of preparing it was mostly based on toluene in the past, and it was obtained by chlorination. However, the old method has many disadvantages, such as the yield is not perfect, and the by-products are complicated.
In order to improve, I have tried my best to improve the process. Try a new catalytic system and optimize the reaction conditions. After repeated tests, the temperature, pressure, and catalyst dosage are all delicately controlled.
Compared with the past, the yield has increased significantly, and the by-product has decreased sharply. And the product purity is better, which is enough to meet the needs of many parties. Looking forward to the future, I hope this research can promote its wide use in the fields of medicine, pesticides and materials, so as to achieve greater success and be used by the world.
Toxicity Research
Since modern times, chemical techniques have advanced, and various products have emerged one after another. The study of the toxicity of 4-Chlorotoluene is quite important.
Guanfu 4-Chlorotoluene, although it has been used in various industrial fields, its toxicity cannot be ignored. On the way into the body, either through breathing or through skin contact. Its toxicity can disturb the normal operation of the human body and damage the viscera.
After experimental investigation, mice exposed to an environment containing 4-Chlorotoluene have long been seen to behave abnormally, or to be tired, and their organs are also showing signs of disease. As for people, long-term exposure to it may also cause health problems, such as respiratory diseases, or even hinder the ability to make blood.
Therefore, the use of 4-Chlorotoluene should be used with caution. The industry must strictly abide by regulations and take good protection to prevent its poison from endangering everyone. This sincerity is related to the health of people's livelihood and cannot be ignored.
Future Prospects
Fu 4 - Chlorotoluene has a wide range of uses in today's chemical industries. Looking at its past, it has been researched and researched by various workers for its own sake, and the production method has gradually refined, and the production has also increased day by day.
Thinking about the future, the progress of science and technology cannot be limited. There must be new techniques to make the product purer, and to reduce consumption and energy saving. It is used in medicine and materials, or has new uses, to expand endless fields.
Also read about the chemical industry, constant care and environmental protection. Those who make 4 - Chlorotoluene in the future will definitely be able to manage waste and pollution well, in line with the laws of nature, and do not damage the ecology. In this way, the karma of 4-Chlorotoluene has a bright future, which can be used for future generations, and it can be used for unlimited hope in the unfinished time.
Frequently Asked Questions
What are the main uses of 4-Chlorotoluene?
4-Chlorotoluene, as well as organic compounds, has a wide range of uses. In the industrial field, it is a key raw material for the synthesis of many organic compounds.
First, in the manufacture of pesticides, it can be used as an intermediate. Due to its structural characteristics, the lid can react with other compounds to generate pesticide products with insecticidal and herbicide effects. If a series of reactions can be carried out, pesticides with specific effects on specific pests can be prepared, providing assistance for the pest control of agricultural production, ensuring the growth of crops and increasing harvests.
Second, it also plays an important role in the synthesis of medicines. Through various chemical reactions, 4-chlorotoluene can be converted into compounds with medicinal value. Or as a key structural fragment of a certain type of drug, after further modification and synthesis, it can be made into a drug to treat specific diseases and serve human health.
Third, in the dye industry, 4-chlorotoluene also plays an important role. It can be used as a starting material to synthesize dyes with bright color and stable performance through multi-step reaction. Such dyes are widely used in textile, printing and dyeing industries to give fabrics rich and colorful colors and meet people's needs for textile aesthetics.
In addition, 4-chlorotoluene has also been involved in the field of fragrance synthesis, which can provide a unique chemical structure for the creation of fragrances and add a different aroma.
What are the physical properties of 4-Chlorotoluene?
4-Chlorotoluene is one of the organic compounds. Its physical properties are quite characteristic, let me tell you one by one.
Looking at its properties, under room temperature and pressure, 4-chlorotoluene is in the state of a colorless and transparent liquid, which is clearly recognizable.
When it comes to smell, it has an aromatic smell and has a unique smell, which can be perceived by humans in the air.
Besides, its boiling point is about 162 ° C. At this temperature, 4-chlorotoluene changes from liquid to gaseous state, realizing a phase change.
In terms of melting point, it is -35 ° C. When the temperature drops below this point, 4-chlorotoluene condenses from liquid to solid.
Density is also an important property. The density of 4-chlorotoluene is greater than that of water, about 1.07 g/cm ³. When mixed with water, it can be seen that it sinks to the bottom of the water.
In terms of solubility, 4-chlorotoluene is insoluble in water, which is due to its molecular structure characteristics. However, it is soluble in organic solvents such as ethanol, ether, and benzene, and can be well miscible in such solvents.
In terms of volatility, 4-chlorotoluene has a certain degree of volatility. In the normal temperature environment, the molecule gradually escapes into the air, causing its concentration in the environment to gradually change.
In addition, the vapor of 4-chlorotoluene is heavier than air and accumulates at low levels. This characteristic needs to be paid attention to in specific scenarios to prevent potential safety hazards.
All these physical properties are key factors to consider when applying 4-chlorotoluene in many fields such as chemical industry and medicine, and have important guiding significance for its operation, storage, transportation and other aspects.
What are the chemical properties of 4-Chlorotoluene?
4-Chlorotoluene, its chemical properties are as follows:
4-chlorotoluene is an organic compound with dual characteristics of aromatics and halogenated hydrocarbons. As far as the characteristics of aromatics are concerned, its benzene ring can undergo electrophilic substitution reaction. Because of its methyl group as the power supply group, the electron cloud density of the benzene ring increases, so the electrophilic substitution reaction activity is higher than that of benzene. Under suitable conditions, a nitration reaction can occur, and the nitro group is mainly introduced into the methyl ortho and para-sites. For example, by co-heating with concentrated nitric acid and concentrated sulfuric acid mixed with acid, 2-nitro-4-chlorotoluene and 4-nitro-4-chlorotoluene are obtained. In addition, a sulfonation reaction can also occur, and the sulfonic acid
In terms of the characteristics of halogenated hydrocarbons, the chlorine atoms can undergo a substitution reaction. Under alkaline conditions, such as co-heating with aqueous sodium hydroxide solutions, the chlorine atoms can be replaced by hydroxyl groups to form 4-methylphenol. If reacted with nucleophiles such as sodium alcohol, the chlorine atoms can be replaced by alkoxy groups. At the same time, the chlorine atoms in 4-chlorotoluene can also undergo elimination reactions under certain conditions. For example, heating in potassium hydroxide alcohol solution can eliminate hydrogen chloride to form p-methylstyrene.
4-chlorotoluene is flammable, and can be burned in case of open flames and hot topics. Toxic chloride fumes will be produced when burned. Its chemical properties make it widely used in the field of organic synthesis and can be used as an intermediate for the synthesis of a variety of drugs, pesticides, and other organic compounds.
What are the production methods of 4-Chlorotoluene?
4-Chlorotoluene, also known as p-chlorotoluene, is prepared by roughly three methods.
One is the chlorination of toluene. With toluene as the starting material, under the action of light or catalyst, chlorine atoms are introduced. During photoluminescence chlorination, the chlorine radical will grab the hydrogen on the toluene methyl group to form a benzyl radical, which will then react with chlorine to obtain benzyl chloride. The re-isomerization of benzyl chloride can produce 4-chlorotoluene, and there are also by-products such as 2-chlorotoluene. However, if a catalyst is used, such as an iron-based catalyst, the reaction mainly occurs on the benzene ring, and the chlorine atom preferentially replaces the para-hydrogen of the benzene ring. Because methyl is an ortho-para-site locator, the para-site steric resistance is small, and the reactivity is suitable, 4-chlorotoluene with higher yield can be obtained.
The second is the diazotization of p-toluidine. First, p-toluidine is reacted by diazotization to generate a diazo salt, and then interacts with cuprous chloride and other reagents. The diazo group is replaced by a chlorine atom to obtain 4-chlorotoluene. In this way, the starting material p-toluidine is relatively easy to obtain, the diazotization reaction conditions are relatively mild, and the selectivity is
The third is the reduction method of p-chlorobenzoic acid. After the treatment of p-chlorobenzoic acid with suitable reducing agents, such as lithium aluminum hydride, the carboxyl group is reduced to methyl, and 4-chlorotoluene is obtained. The raw material of this route is not difficult to find p-chlorobenzoic acid. Although the reduction reaction requires specific conditions and reagents, the target product can be accurately prepared, but attention should be paid to the safety of the use of the reducing agent and the convenience of post-processing.
All kinds of production methods have advantages and disadvantages. In industrial production, it is necessary to weigh and choose according to the source of raw materials, cost, product purity and many other factors.
What are the precautions for using 4-Chlorotoluene?
For 4-chlorotoluene, it is also a commonly used substance. In the process of its use, several things should be paid attention to.
The first priority is safety, and 4-chlorotoluene is toxic and flammable. When handling this material, you must wear appropriate protective equipment, such as gas masks, protective clothing and gloves, to avoid contact with the body and inhalation to the lungs. And the place of operation should be well ventilated, and fire and explosion-proof measures are also indispensable. It is easy to ignite and explode in case of open flames and hot topics.
The second time is related to storage. It should be stored in a cool and ventilated warehouse, away from fire and heat sources. It should be stored and transported separately from oxidants and edible chemicals. Do not mix storage and transportation. The storage area should be equipped with leakage emergency treatment equipment and suitable containment materials to prevent accidents.
Furthermore, when using, it is necessary to precisely control the amount and reaction conditions. The factors involved in the reaction, such as temperature, pressure, catalyst, etc., all have a huge impact on the rate of reaction, the purity and yield of the product. Therefore, before use, the reaction mechanism and conditions must be carefully studied, and the operation should be carried out according to the specifications.
In addition, the treatment after use should not be ignored. Waste containing 4-chlorotoluene should not be disposed of at will, but should be properly disposed of in accordance with environmental protection regulations. Or recycled and reused, or through harmless methods to minimize its harm to the ring.
In short, the use of 4-chlorotoluene requires caution in safety, storage, use, and post-processing to avoid disasters and make the best use of it.