Qiji Chemical
Products

Bromobenzene

Qiji Chemical

Bromobenzene
Specifications

HS Code

478672

Name Bromobenzene
Chemical Formula C6H5Br
Molar Mass 157.01 g/mol
Appearance Colorless to pale yellow liquid
Odor Sweet, aromatic odor
Density 1.495 g/cm³
Melting Point -30.8 °C
Boiling Point 156.2 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in ethanol, ether, benzene
Flash Point 51.7 °C
Vapor Pressure 1.33 kPa at 40.4 °C
Refractive Index 1.5597
Packing & Storage
Packing Bromobenzene packaged in 500 - mL glass bottles, ready for chemical use.
Storage Bromobenzene should be stored in a cool, well - ventilated area, away from heat sources and ignition points due to its flammability. Keep it in a tightly - sealed container to prevent vapor leakage. Store separately from oxidizing agents, as they can react. Ideal storage temperature is around 2 - 8°C in some cases, and ensure the storage area has proper spill - containment measures.
Shipping Bromobenzene is shipped in tightly - sealed, corrosion - resistant containers, often made of steel or specific plastics. It's transported under cool, dry conditions, following strict hazardous material regulations to prevent spills and ensure safety during transit.
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Bromobenzene Bromobenzene
General Information
Historical Development
Bromobenzene is also an organic chemical. Its traces can be traced back to the dawn of chemistry in the past. At the beginning, all virtuous researchers studied the mystery of chemistry and dedicated themselves to the exploration of new quality.
At that time, chemists, with their wisdom and diligence, repeatedly sought in the laboratory. After many attempts and experimental changes, the method of producing bromobenzene was finally obtained.
Its method gradually improved, from crude at the beginning to sophisticated at the later. With the passage of time, science and technology have advanced, and the technique of preparing bromobenzene has also changed with each passing day. In the past, manual operation was used, but now the equipment is precise, and the output and quality have increased significantly. Bromobenzene is widely used in the field of chemical industry, and it is required by many industries. Its historical evolution is one of the evidences of chemical development, witnessing the wisdom and hard work of many scholars, and also opening the way for future exploration.
Product Overview
"Bromobenzene"
Bromobenzene is also an organic compound. It is a colorless and transparent liquid with a special aromatic odor. The density is higher than that of water, and it is insoluble in water, but it can be miscible in organic solvents such as alcohols, ethers, and benzene.
The preparation of bromobenzene is often obtained by the reaction of benzene and bromine under the catalysis of iron filings. This reaction is violent and needs to be carefully controlled. It has a wide range of uses and is often an important intermediate in the field of organic synthesis. It can be derived from various organic compounds through many reaction paths, and has important applications in medicine, pesticides, dyes and other industries.
However, bromobenzene is also dangerous. Its vapor is toxic and can be inhaled or absorbed through the skin, which can endanger human health. Therefore, when producing, storing and using, it is necessary to strictly abide by safety procedures and take protective measures to ensure personal safety and environmental safety.
Physical & Chemical Properties
"On the Physical and Chemical Properties of Bromobenzene"
Bromobenzene is also an organic compound. Its shape is a colorless and transparent liquid with a special aromatic odor. The boiling point is about 156.2 ° C, the density is higher than that of water, 1.495g/cm ³, insoluble in water, easily soluble in organic solvents such as alcohols, ethers, and benzene.
From the perspective of chemical properties, bromine atoms in bromobenzene are more active. Although the conjugation effect of the electron cloud of the benzene ring increases its stability, under certain conditions, substitution reactions can still occur. If iron is used as a catalyst, it can interact with iron bromide, further electrophilic substitution occurs, and other groups are introduced. Because the electron cloud density distribution of the benzene ring is affected by the bromine atom, the adjacent and para-position electron cloud density is relatively high, which is conducive to the attack of electrophilic reagents. Its chemical stability is stronger than that of ordinary halogenated hydrocarbons, but it can also exhibit various chemical activities under suitable conditions, and is widely used in the field of organic synthesis.
Technical Specifications & Labeling
"Technical Specifications and Labels of Bromobenzene (Commodity Parameters) "
Bromobenzene is an organic chemical. Its technical specifications, the first purity. To obtain high-purity bromobenzene, the preparation method needs to use benzene and bromine, accompanied by iron filings as catalysts, moderate temperature control, to prevent its side-effects, so that the purity of bromobenzene can reach the standard of commercial regulations.
As for the label, on the package, the name of "bromobenzene" must be stated, with its chemical formula C-H-Br. It is also marked with warning words to inform its toxicity and flammability. Detailed commodity parameters, such as molecular weight, density, boiling point, etc., so that users can understand its physical properties and use it safely. When
is prepared, it can be used to preserve the quality of bromobenzene and be suitable for world use when complying with regulations, verifying its quality and meeting specifications.
Preparation Method
The raw materials and production process are the key to the production of bromobenzene. Benzene and bromine are often used as raw materials, and iron filings are used as catalysts. First put benzene in the flask, slowly inject bromine, during which iron filings catalyze, leading to a violent reaction.
In the reaction step, bromine molecules are polarized under iron catalysis, and the benzene ring electron cloud attracts bromine positive ions to form an intermediate. After the intermediate loses hydrogen ions and forms bromobenzene.
The production process needs to control temperature to prevent side reactions. The volatile reactants are refluxed in a condensing device to improve the utilization rate of raw materials. And the tail gas contains hydrogen bromide, which is absorbed by alkali solution to avoid pollution. In this way, bromobenzene can be efficiently prepared, and its principle and process can be explained to ensure the smooth production and
Chemical Reactions & Modifications
Taste the wonders of chemistry, it is related to the changes of all things. When discussing the chemical reaction and modification of Bromobenzene today, the reason is profound.
Bromobenzene is also an organic compound. Its reaction is changeable, and it can interact with magnesium to form Grignard's reagent, which is a powerful tool for organic synthesis and can open the door to many reactions. It can also react with nucleophiles to produce a variety of products.
As for modification, chemists often think about changing its structure, increasing its activity, or adjusting its physical properties. It can be added to the benzene ring with other groups to change the distribution of its electron cloud, causing the reaction activity to vary. In this way, Bromobenzene can meet more synthetic needs, contribute to the development of organic chemistry, and generate new products for the benefit of the world.
Synonyms & Product Names
Bromobenzene is also an organic compound. Its aliases are also numerous, such as bromobenzene, which is the same thing and alias corresponding to "Bromobenzene". Its shape is colorless, aromatic, but toxic and flammable.
In the field of chemical industry, it has a wide range of uses. It can be used as a raw material for organic synthesis. If you prepare phenyl Grignard reagent, this reagent is crucial in the formation of carbon-carbon bonds and other reactions. It can also be used in the pharmaceutical industry and is an intermediate for the synthesis of various drugs. In the field of materials science, it is also a key component in the preparation of specific functional materials.
Looking at its market, the name "Bromobenzene" often appears in the directory of various chemical products, parallel to the synonymous names such as bromobenzene. Manufacturers use it as raw materials to produce many downstream products, which play a role in industrial development and are indeed important chemicals.
Safety & Operational Standards
Safety and Operating Specifications of Bromobenzene
Bromobenzene is also an organic compound, and is widely used in the fields of chemical industry and medicine. However, it has certain dangers, so when operating, we should strictly abide by safety and operating standards.
In terms of safety, bromobenzene is toxic. Inhalation, ingestion or skin absorption can endanger human health. In light cases, it can cause headache, dizziness, nausea, vomiting, and in severe cases, it may damage the functions of organs such as liver and kidney. And it is flammable, and can burn and explode in case of open flames and hot topics.
Operating Specifications First protection. Operators work in a well-ventilated environment in front of protective clothing, protective gloves and goggles to prevent the inhalation of bromobenzene vapor. When taking bromobenzene, it is advisable to use special equipment and handle it with care to avoid spillage.
If you accidentally spill it, quickly evacuate unrelated personnel to a safe area and cut off the fire source. Small spills can be absorbed by inert materials such as sand and vermiculite and collected in a closed container; if you spill a large amount, you need to build a dike or dig a pit for containment, cover it with foam to reduce steam disasters, and then ask professionals to deal with it.
Store bromobenzene in a cool, ventilated warehouse, away from fire and heat sources, and store it separately from oxidants and acids. Do not store it in a mixed storage. The warehouse should be equipped with emergency treatment equipment for leaks and suitable containment materials.
During the experimental operation, strictly follow the experimental steps and control the reaction conditions, such as temperature, pressure, etc. After the reaction is completed, properly dispose of the remaining bromobenzene and do not dump it at will.
In short, the operation of bromobenzene must be cautious, strictly abide by safety and operating standards, in order to ensure the safety of personnel and the environment from pollution, and to enable bromobenzene to play its due role in various fields.
Application Area
Bromobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it is often used as a key intermediate. If some specific drugs are prepared, bromobenzene participates in the reaction and can help form a specific molecular structure to achieve the purpose of treating diseases.
In the field of materials science, it also has important uses. It can be integrated into polymer materials through specific processes to improve its properties, such as improving the stability and heat resistance of materials, so that the materials are suitable for more special environments.
In fine chemicals, bromobenzene is a raw material for many fine chemicals. After a series of chemical reactions, a variety of high-value-added products can be prepared, which can be used in flavors, dyes and other industries to enrich product types and improve product quality. Overall, bromobenzene plays an important role in many fields, promoting the development of related industries.
Research & Development
The industry of chemical industry is changing with each passing day, and the research of substances is related to people's livelihood. Today, Bromobenzene (Bromobenzene) has been studied in the academic world for a long time.
Bromobenzene has a clear color and a different taste, and its properties are relatively stable. In the past, many people studied it, and the method of making it was first obtained, but it was time-consuming and laborious, and the production was not yet abundant. After several generations of research, the process was improved, and its production was rising. In the field of organic synthesis, bromobenzene is an important agent, helping to form all kinds of delicate combinations and exploring the path of chemical development.
We continue to go to Saint's will to cultivate its principles. Hope to optimize the process, reduce its energy consumption, and increase its quality and quantity. Also think of expanding its use, in medicine, materials industries, explore a new way. With unremitting research, so that bromobenzene in the future development, more ambitious, benefit Wanfang.
Toxicity Research
"Study on the toxicity of bromobenzene"
The toxicity of bromobenzene is now studied. It is an organic compound and has many applications in chemical industry. I have investigated its properties in detail to study the effect on living things.
After various experiments, it has been observed that if bromobenzene enters the body, it can damage the viscera. When mice try it, they often show a state of depression and eat less. It may invade the liver and spleen, causing changes in organ function.
And when it is applied to plants, bromobenzene is applied to the soil, the growth of plants is blocked, the leaf color is yellow, and the development is delayed. This shows that bromobenzene is toxic.
However, if we want to clarify its details, we need to study it extensively, explore the source of its toxicology, and seek ways to avoid harm. At the same time, it is used in industry to ensure the safety of all beings and ecological harmony.
Future Prospects
Bromobenzene is also an organic chemical. In today's world, the chemical industry is thriving, and the use of bromobenzene is becoming more and more widespread. Looking at its future prospects, there are many ends.
Bromobenzene can be used in the field of pharmaceutical synthesis, or it can be the basis for new agents, help the progress of medicine, and solve the pain of many diseases. In the way of material research and development, it can participate in the production of new materials, add materials to special functions, and use them in various appliances. And with the rapid progress of technology, the preparation process of bromobenzene is also expected to be optimized, reducing its consumption, improving its production, and reducing costs.
Although the road ahead may be difficult, with the current trend of science and technology and the heart of research, bromobenzene will be able to develop its talents in various fields in the future, contributing to the well-being of mankind and the progress of society.
Frequently Asked Questions
What are the physical properties of Bromobenzene?
Bromobenzene is also an organic compound. It has unique physical properties and can be described in detail.
Looking at its properties, it is a colorless oily liquid at room temperature with a dense texture. Smell it, there is a special aromatic gas, but this gas may be irritating, so be careful when using it.
In terms of its melting and boiling point, the melting point is -30.7 ° C, and the boiling point is 156.2 ° C. Because the boiling point is quite high, more heat needs to be applied to vaporize it. This property is of great significance in chemical operations such as separation and purification.
Bromobenzene has a density greater than that of water, about 1.50g/cm ³. When it is mixed with water, it can be clearly seen that it sinks to the bottom of the water. This density difference is different from that in many experiments and industrial processes, which facilitates the separation of bromobenzene from water or other low-density substances.
In terms of solubility, bromobenzene is insoluble in water. Because bromobenzene is a non-polar molecule, while water is a polar molecule, according to the principle of "similar miscibility", the two are insoluble. However, bromobenzene is soluble in organic solvents such as alcohols, ethers, and benzene. This property makes it often used as a solvent or a medium to participate in reactions in organic synthesis.
Bromobenzene has relatively low volatility, and its volatilization rate is relatively slow at room temperature and pressure. This point is easier to control its escape during storage and use, but it should not be careless. It still needs to be properly stored to avoid environmental pollution and safety hazards caused by its leakage.
In short, bromobenzene has unique physical properties and plays a key role in the field of organic chemistry and industrial production. Only by knowing its properties can it be used effectively.
What are the chemical properties of Bromobenzene?
Bromobenzene is also an organic compound, which has various chemical properties.
First of all, its stability. The structure of bromobenzene is relatively stable, and the benzene ring has a conjugated system, which makes its chemical properties different from that of ordinary halogenated hydrocarbons. Under normal temperature and pressure, bromobenzene is more difficult to react spontaneously, and can be placed in the air for a long time without significant qualitative change. Because its carbon-bromine bond has a certain strength, it is not easy to break.
times and nucleophilic substitution reactions. Although it is more difficult than ordinary halogenated alkanes, under certain conditions, the bromine atomic energy of bromobenzene is replaced by nucleophilic reagents. Under the condition of strong base and high temperature, nucleophilic reagents can attack the carbon attached to bromine on the benzene ring, causing bromine to leave in the form of bromine ions, and then form new compounds. This reaction mechanism is slightly complicated, due to the distribution of electron clouds in the benzene ring, nucleophilic reagents need to overcome a certain energy barrier before they can react.
Re-discussion of its electrophilic substitution reaction. The benzene ring is rich in electrons and is vulnerable to attack by electrophilic reagents. On the benzene ring of bromobenzene, the bromine atom is the o-site and para-site locator. When encountering electrophilic reagents, the electrophilic substitution reaction mostly occurs in the ortho-site and para-site of the bromine atom. The lone pair electrons of the marginal bromine atom can be conjugated However, the bromine atom has an electron-absorbing induction effect, which reduces the electron cloud density of the benzene ring to a certain extent, so the electrophilic substitution activity of bromobenzene is slightly lower than that of benzene.
has a reduction reaction. Under the action of appropriate reducing agents, the carbon-bromine bond of bromobenzene can be reduced and broken, and the bromine atom is replaced by hydrogen atom to generate benzene. This process requires specific catalysts and suitable reaction conditions to promote electron transfer and chemical bond recombination.
Bromobenzene has unique chemical properties, coexistence of stability and various reaction characteristics, and is widely used in the field of organic synthesis, providing an important way for the preparation of many organic compounds.
What are the main uses of Bromobenzene?
Bromobenzene is also an organic compound. It has a wide range of uses and has important applications in the fields of industry and scientific research.
The primary use is as a raw material for organic synthesis. Cover bromobenzene can undergo many chemical reactions to prepare other organic compounds. For example, under the action of metal catalysts, bromobenzene can react with magnesium to form Grignard reagents. This reagent is extremely critical in organic synthesis. It can react with carbonyl compounds such as aldose and ketone to obtain alcohols. This is an important means of building carbon-carbon bonds and helps to build the structure of organic molecules.
Furthermore, bromobenzene is also used in drug synthesis. In the preparation of many drugs, bromobenzene is often used as a starting material or a key intermediate. Through the chemical modification of p-bromobenzene, specific functional groups can be introduced to construct molecular structures with specific pharmacological activities, providing an important material basis for the research and development of new drugs.
In the field of materials science, bromobenzene also has its uses. It can participate in the synthesis of polymer materials, through polymerization, etc., the bromobenzene structure is introduced into the polymer chain, giving the material unique properties, such as improving the flame retardancy and thermal stability of the material, to meet the needs of different fields for material properties.
In addition, bromobenzene is also used in the dye industry. It can be converted into bromine-containing dye intermediates through chemical reactions, and then synthesized into various colorful and high-performance dyes, which are used in fabric dyeing and other industries to enrich people's lives.
What are the synthesis methods of Bromobenzene?
Bromobenzene, organic compounds are also synthesized by many methods. The following is a detailed description of various production methods.
First, benzene is used as a starting material and bromobenzene can be obtained by bromination reaction. This is a classic method. The method is as follows: first take an appropriate amount of benzene, place it in a reactor, use iron or iron tribromide as a catalyst, and slowly add bromine. During this time, benzene and bromine underwent a substitution reaction under the action of the catalyst. The chemical reaction equation is: $C_ {6} H_ {6} + Br_ {2}\ xrightarrow [] {FeBr_ {3}} C_ {6} H_ {5} Br + HBr $. When reacting, it is necessary to pay attention to control the reaction temperature to prevent the occurrence of side reactions. Because bromine is highly corrosive and the reaction will produce hydrogen bromide gas, the operation should be carried out in a well-ventilated environment, and the exhaust gas should be properly handled to avoid polluting the environment.
Second, bromobenzene can be prepared from Grignard reagent. First, magnesium strips are reacted with halogenated hydrocarbons to obtain Grignard reagent. For example, magnesium reacts with bromoethane to generate ethyl magnesium bromide. Then, ethyl magnesium bromide is reacted with bromine, and bromobenzene can be obtained through a series of conversions. This process is more complicated, and the reaction conditions need to be precisely controlled. An anhydrous and anaerobic environment is particularly critical, otherwise Grignard reagent is
Third, bromobenzene can also be synthesized by the reaction of aryl diazonium salts. First, aniline reacts with nitrous acid under low temperature and acidic conditions to form diazonium salts. Subsequently, the diazonium salt is mixed with cuprous bromide and hydrobromic acid to undergo a Sandmeier reaction, and the diazonium group is replaced by bromine atoms to obtain bromobenzene. This method has a little more steps, and the stability of diazonium salts is not good. Special care should be taken during preparation and use to prevent its explosion.
The above methods have advantages and disadvantages. In actual synthesis, appropriate synthesis methods should be carefully selected according to factors such as the availability of raw materials, the difficulty of reaction conditions, the requirements of yield and purity.
What are the precautions for storing and transporting Bromobenzene?
Bromobenzene, organic compounds are also, when storing and transporting, many matters need to be paid attention to.
First of all, storage must be placed in a cool and well-ventilated place. This is dangerous due to heat exposure to bromobenzene. If it is in a high temperature environment, there may be a risk of increased volatilization, and its vapor mixed with air can form an explosive mixture, which can cause combustion and explosion in case of open flame and high heat. The temperature of the warehouse should be controlled at not more than 37 ° C.
Furthermore, storage must be kept away from fire and heat sources. All fire sources can cause bromobenzene to explode, so be highly vigilant. At the same time, it should be stored separately with oxidants and food chemicals to prevent chemical reactions and endanger safety. Due to its certain toxicity, if it is mixed with edible chemicals, once it leaks or contaminated, the consequences will be unimaginable.
Packaging should not be ignored, and it must be sealed tightly to prevent leakage. Packaging materials should be resistant to bromobenzene corrosion to ensure safe storage.
As for transportation, transportation vehicles must be equipped with corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment. During driving, drivers and escorts must pay close attention and must not leave their posts at will. During transportation, they must also follow the prescribed route and do not stop in densely populated areas and residential areas.
The loading and unloading process should be particularly cautious. Operators should wear suitable protective equipment and handle it lightly. They must not operate brutally to avoid leakage of bromobenzene due to package damage.
All of these are the key precautions for the storage and transportation of bromobenzene. A little negligence can lead to a disaster, which cannot be ignored.