Qiji Chemical
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1,4-Dibromobutane

Qiji Chemical

1,4-Dibromobutane
Specifications

HS Code

120664

Chemical Formula C4H8Br2
Molar Mass 215.91 g/mol
Appearance Colorless to light - yellow liquid
Boiling Point 194 - 196 °C
Melting Point -20 °C
Density 1.787 g/cm³ at 20 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in most organic solvents like ethanol, ether
Odor Characteristic, pungent odor
Flash Point 78 °C
Packing & Storage
Packing 1,4 - Dibromobutane packaged in 500 - mL glass bottles, 10 bottles per carton.
Storage 1,4 - Dibromobutane should be stored in a cool, dry, well - ventilated area away from heat sources and ignition points. It should be kept in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, bases, and reactive metals as it may react with them. Use appropriate secondary containment to prevent spills from spreading.
Shipping 1,4 - Dibromobutane is shipped in tightly - sealed, corrosion - resistant containers. It must be transported in accordance with hazardous chemical regulations, ensuring proper labeling, isolation from incompatible substances, and a safe shipping environment to prevent leakage and risks.
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1,4-Dibromobutane 1,4-Dibromobutane
General Information
Historical Development
1,4-Dibromobutane is also an organic compound. Tracing its historical development, chemists in the past explored its physical properties. After many attempts, their understanding of it was still shallow at first. However, with the passage of time, people have worked tirelessly to analyze its structure and understand its properties. In the past, the synthesis method was quite complicated, time-consuming and laborious, and the yield was not good. After several generations of improvement, new techniques gradually emerged, and the efficiency and purity increased. In the chemical industry, its use has become more and more extensive, either as a raw material or as a reagent. In their exploration, chemists have developed their understanding of 1,4-dibromobutane from shallow to deep, and the process has changed from clumsy to clever. Its historical development is a witness to chemical exploration, paving the way for future research and promoting the prosperity of chemical industries.
Product Overview
1,4-Dibromobutane is also an organic compound. It is a colorless and transparent liquid with a special odor. This compound is widely used in the field of organic synthesis.
The method of preparation is often obtained by the addition reaction of butene and bromine. During the reaction, the double bond of butene is active, and the bromine atom in bromine is combined with it to form 1,4-dibromobutane.
It can be used as an intermediate in organic synthesis. With its dibromine atom, it can react with many reagents to produce other organic compounds. For example, it can react with nucleophiles to introduce other functional groups, thereby expanding the structure and properties of organic molecules.
In industry and laboratories, 1,4-dibromobutane is required. However, when using it, it is also necessary to pay attention to its toxicity and safety, and operate according to regulations to avoid hazards.
Physical & Chemical Properties
1,4-Dibromobutane is also an organic compound. Its color is clear and transparent, like a liquid, with a specific odor. The boiling point is quite high, between 198 and 200 ° C. This property allows it to remain liquid at a certain temperature, which is conducive to many chemical operations. Its density is greater than that of water, about 1.78 g/cm ³, and it sinks at the bottom when placed in water.
In terms of solubility, it is slightly soluble in water, but it can be miscible with organic solvents such as ethanol and ether. This solubility property has important applications in the process of chemical synthesis and separation and purification. In terms of chemical properties, the bromine atom in 1,4-dibromobutane has high activity and is prone to substitution reactions. It can interact with a variety of nucleophiles to generate various derivatives. It is widely used in the field of organic synthesis and is an important intermediate for the preparation of complex organic compounds.
Technical Specifications & Labeling
1,4-Dibromobutane is also an organic compound. The technical specifications and labeling (product parameters) for its preparation are related to the quality and application of this product.
The preparation method should follow strict procedures. The choice of raw materials must be pure; the reaction conditions, such as temperature, pressure, and catalyst dosage, must be precisely controlled. In this way, high-purity 1,4-dibromobutane can be obtained.
In terms of labeling, the name, chemical formula, purity, molecular weight and other parameters should be stated on the packaging of the product. And marked with warning words to inform users of the properties and precautions of this product, so that it can be used safely. In accordance with this technical specification and labeling, the production and use of 1,4-dibromobutane can be orderly and safe.
Preparation Method
The preparation of 1,4-dibromobutane is related to raw materials and production processes, reaction steps and catalytic mechanisms. Butanol and hydrobromic acid are commonly used as raw materials. The preparation method is to react butanol and hydrobromic acid under the catalysis of sulfuric acid. In this case, sulfuric acid is used as a catalyst to accelerate the reaction process.
The reaction steps are as follows: First, butanol, hydrobromic acid and sulfuric acid are mixed in appropriate proportions, and heated and refluxed at a specific temperature. In this process, the hydroxy group of butanol is replaced by a bromine atom to generate 1,4-dibromobutane. After the reaction is completed, the product is purified through separation, washing, drying and other processes.
The catalytic mechanism is that sulfuric acid enhances the activity of bromine ions in hydrobromic acid, making it easier to replace with butanol. In this way, the 1,4-dibromobutane product can be obtained by means of reasonable raw material ratio, precise reaction step control and effective catalytic mechanism.
Chemical Reactions & Modifications
The anti-modification of 1,4-dibromobutane is of interest in chemical research. In the past, this compound was often used in a specific way, but its efficiency and reaction properties may be improved.

The improvement of this process can not only improve the yield of 1,4-dibromobutane, but also make its production more colorful and efficient. It has a deep value in the field of production and research, and is expected to promote the innovation of phase reduction.
Synonyms & Product Names
1,4-Dibromobutane is also a chemical product. Its name is the name of the product, and it can be investigated.
The name of the product in the world is many, or due to the region, or due to the use. 1,4-Dibromobutane, also known as tetramethyl dibromide, this is the name of the same product. As for the name of the product, or due to the difference of the family. However, they all refer to the same chemical product.
When we study this product, we must study its names to avoid confusion. In the field of chemistry, the name is very important. Only by knowing the same name and the name of the commodity can we study and use the difference, promote the step of research and make good use of this product, and use it for the world.
Safety & Operational Standards
1,4-Dibromobutane is an important chemical in chemical research. During its preparation, use and storage, safety and operating practices are of paramount importance.
When preparing 1,4-dibromobutane, the experimenter should strictly abide by the operating procedures. First, the experimental site must be well ventilated, because 1,4-dibromobutane has certain volatility, if the ventilation is not good, its vapor will accumulate in the air, or cause the experimenter to inhale and damage health. Secondly, during the use of raw materials and the reaction process, the dosage and reaction conditions should be precisely controlled. If the temperature is too high, the reaction may be out of control and unnecessary by-products will be generated, which will not only affect the purity of the product, but also cause safety accidents.
When using 1,4-dibromobutane, the experimenter must take protective measures. Wear suitable protective gloves, as it may be irritating to the skin. At the same time, wear protective glasses to prevent it from splashing into the eyes and causing eye damage. If you accidentally come into contact with the skin, you should immediately rinse with plenty of water and seek medical attention as appropriate. If you splash into the eyes, you need to rinse the eyes with plenty of water immediately and seek medical attention quickly.
There are also strict regulations for storing 1,4-dibromobutane. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its flammability, it can be exposed to open flames, hot topics or cause combustion and explosion. At the same time, it should be stored separately from oxidants, acids, etc., to avoid chemical reactions.
In short, in the entire research and use of 1,4-dibromobutane, safety and operating standards have always been the top consideration. Only by strictly following the relevant guidelines can the experimenter ensure their own safety, and at the same time ensure the smooth development of the experiment and the quality of the product.
Application Area
1,4-Dibromobutane is useful in many fields. In the field of organic synthesis, it is a key raw material. It can be used to prepare a variety of compounds containing butyl structures. After nucleophilic substitution reaction, various functional groups can be introduced, which can be used to create pharmaceutical intermediates, such as some specific anti-inflammatory drugs, to help them form a specific chemical structure.
In the field of materials science, it is also useful. Polymerization with specific polymer monomers can improve polymer properties, improve material toughness and stability, and give the resulting materials unique advantages in packaging, construction and other industries.
Furthermore, in fine chemicals, it is used to synthesize special fragrances, endowing fragrances with unique odor and stability, and increasing its commercial value. From this perspective, 1,4-dibromobutane has a wide application field and is indispensable for the development of the chemical industry.
Research & Development
1,4-dibromobutane, this compound is of great significance in our chemical research. In the past, its preparation method was quite laborious and the yield was not very high. But why would our scientific researchers give up easily?
We studied day and night, consulted many classics, learned from the experience of predecessors, and combined with the current new technology. After repeated experiments, the temperature and pressure of the reaction were adjusted, and the appropriate catalyst was screened. Fortunately, the optimization method can improve the yield of 1,4-dibromobutane and the quality is better.
Looking to the future, 1,4-dibromobutane may be more widely used in the field of organic synthesis. We should make unremitting efforts to explore and tap its potential, so as to promote its excellence in materials, medicine, and other aspects, and contribute our efforts to the progress of scientific research and the development of society.
Toxicity Research
Since modern times, chemical refinement has led to the emergence of many new substances. I am focusing on the toxicity study of 1,4-Dibromobutane.
View 1,4-Dibromobutane, its molecular structure is unique and contains bromine atoms. Bromine, a halogen element, is sexually active. In experiments, this substance initially shows signs of stimulation. Take animals as a test, touch or smell it, and you can see a restless state.
And explore its entry path, which can be penetrated through breathing and skin. After entering the body, it seems to disturb the internal organs, especially the liver and kidney. Liver and kidney, human detoxification and transportation must be central. If it is damaged, biochemical metabolism will be chaotic.
Then investigate its long-term effects, fear-induced gene changes. Looking at cell changes, chromosomes may have aberrations. Although this research is not complete, the signs of toxicity have emerged, and it must be investigated in the future to clarify its harm and ensure the well-being of the public.
Future Prospects
In the field of chemical research, the future development of 1,4 - Dibromobutane is quite promising. This material has unique properties, or in the way of organic synthesis, it is the opening of a new path. In the future, it may be able to make a name for itself in the field of pharmaceutical creation, help the research of new drugs, and solve the pain of the world. Or in the field of material science, it shines brightly, giving rise to materials with strange properties, and is applied to various high-tech fields. Our scientific researchers should use our best understanding and explore its mysteries, with the hope of unremitting research, so that 1,4 - Dibromobutane can develop its endless potential in the future, bring benefits to the world, create a new scene, and live up to the mission of scientific research, hoping for future glory.
Frequently Asked Questions
What are the main uses of 1,4-dibromobutane?
Erxian Decoction is a traditional Chinese medicine prescription, from "Obstetrics and Gynecology" (edited by Shanghai University of Traditional Chinese Medicine). Its main use is quite extensive, in the field of gynecology, it is often used to regulate female endocrine, and has a significant effect on menopausal syndrome. Many women enter menopause, due to the decline of ovarian function, estrogen levels fluctuate or decrease, hot flashes, night sweats, upset insomnia, sore waist and knee and many other discomforts. Erxian Decoction can effectively relieve such symptoms by adjusting the balance of yin and yang.
Analyzed from the theory of traditional Chinese medicine, Erxian Decoction uses Xiancao, Xianling Spleen (Epimedium), and Morinda to warm the kidney and yang, and nourish the kidney essence; Anemarrhena and Huangbai to nourish the kidney and yin, diarrhea and The combination of the whole prescription is exquisite, and the yin and yang are adjusted at the same time, so that the yin and yang in the kidney are balanced, and the qi and blood are reconciled.
In clinical application, in addition to menopausal syndrome, Erxian Decoction also shows good curative effect on endocrine disorders such as polycystic ovary syndrome and premature ovarian failure. Some patients with polycystic ovary syndrome have symptoms such as irregular menstruation, infertility, and hirsutism. The pathogenesis often involves the imbalance of kidney yin and yang. Erxian Decoction can adjust the body's yin and yang, improve the endocrine state, and help restore the normal menstrual cycle and ovulation function.
In addition, in some andrological diseases, if the pathogenesis is consistent with the deficiency of kidney yin and yang, Erxian Decoction may also have certain application value. Some men have symptoms such as sexual dysfunction, sore waist and knee due to insufficient kidney yang and kidney yin deficiency. Erxian Decoction can play a role in warming the kidney and strengthening yang, nourishing yin and filling essence, and improving symptoms.
In summary, Erxian Decoction plays an important role in the treatment of various diseases caused by kidney yin and yang imbalance, relieving pain for many patients.
What are the physical properties of 1,4-dibromobutane?
Mercury disulfide (HgS), also known as cinnabar in ancient times, has the following physical properties:
- ** Color morphology **: It is often bright vermilion, with various crystal forms, commonly rhombohedral, plate-shaped or columnar, and aggregates are lumpy and granular. "Tiangong Kaiwu" says: "Where cinnabar is of high quality, the burrow soil is more than ten feet, and its seedlings are first seen. It is a white stone bed, and there are red spots on the stone, so the stone is taken from it. The big one is like a chicken, and the small one is like a bean grain, which is cinnabar." This description shows the block shape and color characteristics of cinnabar.
- ** Hardness specific gravity **: The Mohs hardness is about 2-2.5, the texture is relatively soft, and the nails can be scratched to leave marks. The specific gravity is large, about 8.0-8.2, and it feels heavy. It has a high density due to the large atomic weight of mercury. As ancient books say, cinnabar of the same volume is heavier than other things.
- ** Glossy Transparency **: With diamond luster to semi-metallic luster. Under the irradiation of light, the surface reflects light and shines brightly. Transparency is translucent to opaque. Those with good quality have good light transmission. Some cinnabar flakes can pass through a small amount of light.
- ** Cleavage characteristics **: The cleavage is incomplete. When it is broken by external force, the fracture surface is irregular, and there is no specific direction to smooth the cracking. This is different from the regular cleavage of some minerals.
- ** Solubility **: Mercury sulfide is chemically stable and insoluble in common solvents such as water, hydrochloric acid, and nitric acid. Only in aqua regia (concentrated hydrochloric acid and concentrated nitric acid mixed at 3:1) or hot concentrated sulfuric acid and other strong oxidizing and strong acidic mixtures, it is slowly dissolved under heating conditions. This property enables cinnabar to exist stably for a long time in nature and in general environments.
What are the chemical properties of 1,4-dibromobutane?
Mercury dimercaptan is a chemical substance with many strange properties. It is often silver-white in color, solid in texture and metallic luster, and shines brightly.
The melting point of this substance is quite low, only -38.87 ° C. Under normal temperatures, it can be turned into a flowing state, like smart mercury, rolling freely on the utensils, slippery without leaving hands. The boiling point is 356.6 ° C. It is easily vaporized into mercury vapor when heated. This vapor is colorless and odorless, but extremely toxic. It pervades the air and quietly erodes human health.
Mercury dimercaptan is chemically stable and does not react easily with oxygen at room temperature. However, under heating conditions, it can combine with oxygen to form mercury oxide. It can interact with many metals to form amalgam, which is quite useful in metallurgy and other fields.
In addition, dimercapto-mercury has good electrical conductivity and is also used in electronic instruments. However, due to its severe toxicity, it is very harmful to the human body. If accidentally exposed to or inhaled its vapor, it will damage the nervous system, kidneys and other important organs, causing tremors, insomnia, kidney failure and many other diseases. Therefore, when using and disposing, it should be extremely cautious and follow strict safety procedures to prevent endangering life and health.
What are the synthesis methods of 1,4-dibromobutane?
The synthesis of disulfide and chlorine, although not detailed in ancient books, is based on today's chemical principles, and there are various ways.
First, sulfur and chlorine are used as raw materials. Sulfur is a common mineral, warm in nature, sour in taste, and toxic. Chlorine is a yellow-green gas, which is highly irritating and corrosive. Heat sulfur to a molten state, and introduce an appropriate amount of chlorine gas, and a chemical reaction can occur between the two. The process is as follows: Sulfur is heated and melted, and sulfur molecules are active. When exposed to chlorine gas, chlorine atoms interact with sulfur atoms to form disulfide and chlorine. This reaction needs to be carried out in a specific container, and the temperature and the amount of chlorine gas must be precisely controlled. If the temperature is too high, the reaction speed will be too high, and the product will be impure; if too much chlorine is introduced, other chlorine-containing sulfides will also be formed.
Second, it can be obtained by reacting other sulfides with chlorine-containing compounds. If a certain sulfur-containing salt and a chlorine-containing halogen are used, under specific reaction conditions, it is also expected to synthesize disulfide and monochlorine through metathesis reaction or oxidation reduction reaction. This method requires fine screening and pretreatment of the raw materials used, and appropriate reaction solvents and catalysts should be selected to promote the reaction and improve the yield and purity of the product.
Or an indirect method can be tried. The intermediate product containing disulfide bonds is first synthesized, and then chlorine atoms are introduced through the chlorination reaction, and finally disulfide and monochlorine are obtained. Although this approach is slightly complicated, the reaction process can be more finely regulated, which is conducive to obtaining high-purity products.
The method of synthesizing disulfide and monochlorine needs to be based on actual conditions and needs, weigh the advantages and disadvantages of each method, choose carefully, and operate carefully to achieve the desired goal.
What should I pay attention to when storing and transporting 1,4-dibromobutane?
When storing and transporting dimercapto monosodium, everyone should pay attention to it.
When storing, the temperature and humidity of the environment should be the first priority. This medicine should be stored in a cool and dry place, protected from high temperature and humidity. High temperature can cause its chemical structure to mutate and reduce its efficacy; moisture can easily lead to deliquescence and damage its quality. The temperature of the warehouse should be controlled within a specific range to ensure its stability.
Furthermore, light is also the key. Dimercapto monosodium should be stored in the dark to prevent light from causing it to decompose. It can be placed in a brown bottle or a container with a shaded package to prevent light intrusion.
and needs to be isolated from other objects. Due to its unique chemical properties, contact with certain substances, or chemical reactions, drug-causing changes. Such as oxidizing agents, acids, alkalis, etc., should be kept away, and it is advisable to store in separate warehouses or partitions.
As for transportation, it should not be ignored. First, the packaging must be stable. Choose solid, sealed packaging materials to prevent damage to the container during transportation and drug leakage. Second, pay attention to the transportation environment. According to storage requirements, control the temperature and humidity in the car. If long-distance transportation, equipment is required to keep the humidity constant. Third, strictly abide by transportation regulations. According to relevant regulations, with suitable transportation tools and personnel to ensure transportation safety, and transportation records are kept in detail for traceability. In this way, only when storing and transporting dimercapto monosodium can its quality and efficacy be guaranteed, and a reliable medicine can be prepared for rescue.