1,6-Dibromohexane

Qiji Chemical

Specifications

HS Code	707690
Name	1,6 - Dibromohexane
Molecular Formula	C6H12Br2
Molar Mass	243.97 g/mol
Appearance	Colorless to light - yellow liquid
Density	1.574 g/cm³
Boiling Point	244 - 245 °C
Melting Point	-2.8 °C
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, ether
Flash Point	117 °C
Odor	Characteristic, pungent

Packing & Storage

Packing	1,6 - Dibromohexane in a 500 - mL glass bottle, tightly sealed for safe storage.
Storage	1,6 - Dibromohexane should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames as it is flammable. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive substances to avoid potential chemical reactions. Ensure storage areas comply with safety regulations.
Shipping	1,6 - Dibromohexane is shipped in sealed, corrosion - resistant containers. These are carefully packaged to prevent leakage during transit. Shipment adheres to strict chemical transportation regulations for safe delivery.

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General Information

Historical Development

1,6-dibromohexane is an organic compound. In the past, in the field of organic synthesis, its preparation and application have gradually flourished. At first, scholars sought it with simple methods, but the results were not apparent. Later, science and technology advanced, and new techniques emerged one after another. Chemists carefully studied and improved the process, so that the yield of 1,6-dibromohexane gradually increased, and the purity was also good. It is widely used in medicine, materials and other industries. It can be used as a raw material for the synthesis of new drugs, or to help optimize the properties of materials. Since its birth, through the efforts of countless chemists, 1,6-dibromohexane has become more and more important in the stage of chemistry, witnessing the development of chemistry and paving the way for future scientific research.

Product Overview

1,6 - Dibromohexane is an organic compound. Its preparation method is often obtained by reacting hexanediol with hydrobromic acid. In this reaction, the hydroxyl group of hexanediol is replaced by a bromine atom and undergoes a nucleophilic substitution process.
1,6 - Dibromohexane has a colorless to light yellow liquid appearance and has specific physical and chemical properties. Its density is greater than that of water, and it is insoluble in water, but it is soluble in common organic solvents such as ethanol and ether.
Because its molecular structure contains two bromine atoms, it is chemically active. It can participate in a variety of organic reactions, such as substitution reactions with nucleophiles, in which bromine atoms are replaced by other functional groups; under the action of strong bases, it can also eliminate reactions to form unsaturated hydrocarbons.
In the field of organic synthesis, 1,6-Dibromohexane is widely used as an intermediate for the preparation of many complex organic compounds, providing an important raw material for organic chemistry research and production.

Physical & Chemical Properties

1,6-Dibromohexane is also an organic compound. Its physical properties are colorless to light yellow liquid at room temperature, with a special odor, insoluble in water, easily soluble in organic solvents such as ethanol, ether, etc. This is because of the similar miscibility. Its boiling point is quite high, about 200 degrees Celsius. Due to the existence of van der Waals force between molecules, it requires higher energy to overcome this force and boil.
In terms of chemical properties, the bromine atom in 1,6-dibromohexane is quite active. When encountering nucleophilic reagents, nucleophilic substitution reactions are prone to occur. If co-heated with sodium hydroxide aqueous solution, bromine atoms can be replaced by hydroxyl groups to obtain 1,6-hexanediol. It can also react with sodium cyanide, and the bromine atom is replaced by a cyano group. The product can be hydrolyzed to obtain adipic acid, which is widely used in organic synthesis.

Technical Specifications & Labeling

For 1,6-dibromohexane, chemical products are also important. In terms of technical specifications, the degree of efficiency is high, and the quality is less. If it contains more, it will affect its use.
In terms of packaging, the name "1,6-dibromohexane" is clearly used to warn the world. Its products, such as molecular weight, boiling, melting, etc., are all refined. This can help users to understand their properties so that they can be used properly. It is indispensable in fields such as chemical research, engineering and biology.

Preparation Method

To prepare 1,6-Dibromohexane, the method is as follows: first take the raw material and synthesize it by a suitable process. Hexadiene and hydrogen bromide can be selected as the initial materials and undergo an addition reaction. Hexadiene has a conjugated double bond. When electrophilic addition to hydrogen bromide, according to Markov's rule, hydrogen is added to the double-bonded carbon with more hydrogen, and bromine is added to the double-bonded carbon with less hydrogen to obtain an intermediate. Subsequently, the intermediate is reduced through a reduction step, and a suitable reducing agent, such as lithium aluminum hydride, can be selected to reduce part of the functional group to obtain the target product 1,6-Dibromohexane. The preparation process requires precise temperature control and time control to ensure that the reaction proceeds according to the predetermined path, and attention is paid to the connection of each step of the reaction to achieve the purpose of efficient synthesis.

Chemical Reactions & Modifications

Nowadays, researchers have studied the chemical reaction of 1,6-Dibromohexane and its chemical properties. To observe its response, they often use other things to complement it, hoping to improve its properties and increase its effectiveness.
In the past, seeking this method of compound may have been cumbersome and inefficient. In the application, the choice of reagents and the control of temperature and time are all related to the result of the application. If the reagent is not suitable, or the temperature is lost, the yield is not high, and the product is impure.
Today's researchers observe the loss of the old method, and explore new ways to improve it. Try different reagents, adjust the environment, and hope to obtain the best method. After many attempts, gradually make progress. Or send mild reagents to make the reaction easy to control; or find the right temperature to promote the reaction speed and increase the yield. This is all an effort to change the reaction and chemical properties of 1,6-Dibromohexane, and it is expected that new gains will be made in the future, so that this compound can be used well in various domains.

Synonyms & Product Names

1,6-Dibromohexane is also an organic compound. Among chemical substances, its name may be another name, and it can also be said to be a synonymous name and a commodity name. This 1,6-dibromohexane is widely used in the chemical field. It can be used as a raw material for organic synthesis. After many reaction steps, various fine chemicals can be prepared. Its synonymous name, or different names according to its structure and nature. And the name of the commodity, or for the manufacturer to take, so as to circulate in the market. For example, chemical merchants, use this material for all parties, all with appropriate names. This 1,6-dibromohexane, with its unique chemical properties, shows its utility in the synthesis path and helps the development of the chemical industry. Whether it is academic research or industrial production, it has an important position, which is related to the name of synonyms and commodities. It is also a key element in the inheritance and application of chemical knowledge.

Safety & Operational Standards

1,6-Dibromohexane is also an organic chemical substance. In the process of my chemical research, its safety and operating standards are of paramount importance.
All handling of this substance should first be placed in a well-ventilated place. It may be volatile, and in an occluded place, its gas accumulates or causes harm. Ventilated places can make its gas dissipate and ensure our safety.
Furthermore, when handling, protective gear is indispensable. It is appropriate to wear protective clothing, which can separate it from the skin and protect the skin from its erosion. And when wearing protective gloves, the material must be able to resist its corrosion. The eye is the window of the soul, and it needs to be protected. Anti-goggles are indispensable to prevent it from splashing into the eyes and damaging my eyes.
As for its use, it should be used in an accurate amount. After using the utensils, be sure to clean them, so that no residue remains, which will cause errors in subsequent experiments. When storing, it should be placed in a cool, dry place, away from fire sources and oxidants. Because of its flammability, it is dangerous in case of fire; contact with oxidants may also cause a violent reaction.
If you accidentally touch the skin, rinse it with plenty of water immediately, followed by fine washing with soap. If it enters the eye, it is even more necessary to rinse it with water immediately and seek medical attention immediately. In the event of a fire, use a suitable fire extinguisher, such as a dry powder fire extinguisher, and do not use water to avoid the spread of the fire.
Our chemical researchers must keep in mind the safety and operating practices of 1,6-dibromohexane, and keep it unswervingly to ensure the smoothness of the experiment and protect their own safety.

Application Area

1,6-Dibromohexane is also an organic compound. Its application field is quite wide. In the field of organic synthesis, it is often used as a key intermediate. The dibromine atom in its structure has active chemical properties and can cause a variety of reactions.
When preparing cyclic compounds, with appropriate reaction conditions, the bromine atom can participate in the cyclization reaction to generate a ring with a unique structure. It is used in the field of medicinal chemistry and lays the foundation for the synthesis of specific drugs. In materials science, it also has its application. After specific chemical reactions, it can be introduced into the structure of polymer materials to improve the properties of materials, such as enhancing the stability and heat resistance of materials. From this perspective, 1,6-dibromohexane plays an important role in many application fields and promotes the development of related disciplines and industries.

Research & Development

I am committed to the study of organic compounds, and recently focused on 1,6-Dibromohexane. The method of its synthesis has been explored several times. At the beginning, I tried it with common methods, but the yield was not ideal. Then I delved into ancient books, referred to the theory of Fang family, and thought about changing the method.
is more specific reagents, temperature control, time adjustment, careful handling. After repeated experiments, the best method was finally obtained, and the yield gradually increased. However, this is not the end, and we still strive to improve the purity of the product.
Looking at this research now, although it has been achieved, there is a long way ahead. In the future, I want to expand its application field, explore its potential in different fields, and hope to gain new things, which will contribute to the development of organic chemistry and achieve new territory.

Toxicity Research

The toxicity of 1,6-Dibromohexane is the focus of chemical research. 1,6-Dibromohexane, which contains chemical compounds, is often used in chemical synthesis.
We have repeatedly studied to investigate its toxicity. Take general organisms, such as mice and kungfu, and apply them to 1,6-Dibromohexane of different degrees. If the mice are exposed to high levels, they will be abnormal, and they will be normal to eat and live. When dissected, it can be observed that there is a bad sign of it, especially the liver and liver.
It is also kungfu, and at high levels, its fertility is blocked, and even died. It can be seen that 1,6-Dibromohexane is toxic. In the use of chemical engineering, care must be taken to prevent its leakage, so as not to endanger the biological environment. The use of this chemical product is to ensure the safety of the product.

Future Prospects

There is a thing today, name 1,6 - Dibromohexane. Our generation is a chemical researcher, and we see this as the hope for the future. This material is unique, and in the field of organic synthesis, the potential is endless.
In the future, it may be used to make exquisite medicines and save thousands of patients from pain. Or it can be used to create high-performance materials, make equipment stronger, and help technology soar.
Although the road ahead is long, we must study it with great dedication and courage to explore its mysteries. In the future, we will be able to show what we can, add brilliance to the world, and live up to this future hope.

Frequently Asked Questions

What are the main uses of 1,6-dibromohexane?

1,6-Dibromoethane is an organic compound, and its main uses are as follows:
First, it is a key raw material for organic synthesis. In the field of organic synthesis, it can be converted into other important organic compounds through many chemical reactions. If it is eliminated, it can generate acetylene, which is an important intermediate for many chemical products such as synthetic rubber and plastics; when reacted with alcohols under alkaline conditions, ether compounds can be prepared. Ethers often play an important role in organic solvents and organic synthesis reactions.
Second, it is used as a solvent. 1,6-Dibromoethane has good solubility and has a good solubility effect on some organic compounds. In some chemical reactions or industrial production processes, it can act as a solvent to help the reactants mix thoroughly and make the reaction easier.
Third, it has applications in the field of agriculture. In the past, it was used as a fumigant to kill pests, pathogens and weed seeds to protect crops from pests and diseases and improve crop yield and quality. However, due to its potential harm to the environment and human health, its use is limited today.
Fourth, it plays a role in pharmaceutical synthesis. In some drug synthesis routes, 1,6-dibromoethane can be used as a starting material or intermediate to participate in the construction of specific structures of drug molecules, which is of great significance for the development and production of certain drugs.

What are the physical properties of 1,6-dibromohexane?

1,6-Dibromohexane is also an organic compound. Its physical properties are quite impressive, and I will describe them in detail for you today.
First of all, under normal temperature and pressure, 1,6-dibromohexane is a colorless to light yellow transparent liquid. The view is clear, and there are no significant impurities mixed in it.
The second time and its smell have a weak special smell, which is not pungent and intolerable. However, if you smell it carefully, you can also distinguish its unique smell. This smell is derived from the chemical properties of its molecular structure.
As for the melting point, it is about -2.7 ° C. When the ambient temperature drops below this point, 1,6-dibromohexane gradually converts from liquid to solid, the movement between molecules slows down, and the arrangement tends to be orderly.
The boiling point is about 241 ° C. If it is heated and the temperature rises to the boiling point, 1,6-dibromohexane will vaporize violently and escape from liquid to gaseous state.
In terms of density, it is about 1.57 g/cm ³, which is higher than that of water. Therefore, if it is placed in one place with water, 1,6-dibromohexane will sink to the bottom of the water.
Solubility is also an important physical property. 1,6-dibromohexane is slightly soluble in water, because water is a polar molecule, while 1,6-dibromohexane has a weaker polarity. According to the principle of "similar miscibility", the degree of miscibility between the two is limited. However, it is soluble in many organic solvents, such as ethanol, ether, chloroform, etc. In such solvents, the molecules of 1,6-dibromohexane and the solvent molecules can mix with each other through intermolecular forces to form a uniform solution.
In addition, the physical properties of 1,6-dibromohexane, such as vapor pressure and surface tension, are also closely related to its molecular structure and intermolecular interactions, which affect its physical behavior in different environments.

What are the chemical properties of 1,6-dibromohexane?

1,6-Dibromohexane is also an organic compound. Its properties are colorless to light yellow liquid, with a special odor. The melting point is fixed, the melting point is about -21 ° C, the boiling point is 244-245 ° C, the density is higher than that of water, about 1.57 g/cm ³, insoluble in water, and miscible in organic solvents such as ethanol, ether, and chloroform.
This substance is chemically active, and many reactions can occur due to the bromine atom. Nucleophilic substitution reactions are common, and bromine atoms can be replaced by nucleophilic reagents such as hydroxyl and amino groups. If co-heated with sodium hydroxide aqueous solution, bromine atoms are replaced by hydroxyl groups to form 1,6-hexanediol; when interacted with ammonia, 1,6-hexanediamine can be obtained.
The elimination reaction can also occur. In strong alkali alcohol solutions, 1,6-dibromohexane can remove hydrogen bromide to form unsaturated compounds. This reaction condition is related to the proportion of reactants, temperature, etc., and the products are different under different conditions.
1,6-dibromohexane has a wide range of uses in the field of organic synthesis. It is an important organic synthesis intermediate and can be used to prepare a variety of drugs, fragrances and polymer materials. In drug synthesis, it provides the basis of carbon chains and functional groups for the construction of complex molecular structures; in fragrance synthesis, it helps to synthesize compounds with unique aromas; in the preparation of polymer materials, it participates in polymerization reactions and imparts specific properties to materials.

What are the synthesis methods of 1,6-dibromohexane?

There are many ways to synthesize 1,6-dibromohexane. First, it can be obtained by reacting hexanediol with hydrobromic acid. Place hexanediol in a reaction vessel, slowly add an appropriate amount of hydrobromic acid, and add a little sulfuric acid as a catalyst to heat to promote the reaction. During this process, the hydroxyl group is replaced by a bromine atom. After careful separation and purification steps, 1,6-dibromohexane can be obtained. The chemical reaction formula is roughly:\ (HO- (CH_ {2}) _ {6} -OH + 2HBr\ stackrel {H_ {2} SO_ {4}} {\ longrightarrow} Br- (CH_ {2}) _ {6} -Br + 2H_ {2} O\).
Second, hexene is used as the starting material. First, hexene is added to bromine. Under suitable reaction conditions, hexene is mixed with carbon tetrachloride solution of bromine, and bromine molecules are quickly added to the double bond of hexene to generate 1,2-dibromohexane. Then, through elimination reaction, heating in ethanol solution of strong base such as sodium ethanol, 1,2-dibromohexane is stripped of a molecule of hydrogen bromide to form 1-bromo-1-hexene. Then, it is added with bromine again, so that 1,6-dibromohexane can be obtained. Although this series of reaction steps is slightly complicated, it is also a feasible method.
In addition, adipic acid can also be used. The reduction of adipic acid to hexanediol, the commonly used reducing agent such as lithium aluminum hydride, can convert the carboxyl group into a hydroxyl group. Then, according to the above method of reacting hexanediol with hydrobromic acid, 1,6-dibromohexane is prepared. This approach requires careful selection of reduction conditions to ensure the smooth progress of the reaction and the purity of the product.
All synthesis methods have their own advantages and disadvantages. In actual operation, when considering the availability of raw materials, the difficulty of reaction, cost and many other factors, the most suitable method is selected.

What are the precautions for storing and transporting 1,6-dibromohexane?

1% 2C6-dibromoethane is a chemical substance. When storing and transporting, many matters need to be paid attention to.
First, when storing, choose a cool and ventilated warehouse. Because 1% 2C6-dibromoethane is easy to decompose when heated, if the warehouse temperature is too high, it may be dangerous. And the warehouse should be kept away from fires and heat sources, and fireworks are strictly prohibited to avoid explosions and other disasters.
Second, it needs to be stored separately from oxidants and alkalis, and must not be mixed. When it comes into contact with oxidants, it is easy to cause violent chemical reactions; co-storage with alkalis may also cause changes in properties and accidents.
Third, the storage container must be well sealed. This is because it is volatile. If the container is not well sealed, the volatile gas will spread, which will damage the environment on the one hand, and increase the gas concentration in the warehouse on the other hand, adding safety hazards.
As for transportation, the transportation vehicle should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. During driving, drivers and escorts must always pay attention to the condition of the goods, and must not park in densely populated places at will. The trough (tank) car used during transportation should have a grounding chain, and holes can be set in the trough to reduce the shock and generate static electricity, so as to prevent the static electricity from causing fire or explosion.
In addition, transportation companies should develop sound transportation plans and emergency plans to ensure that in the event of emergencies, they can respond quickly and effectively to minimize harm. Escort personnel must also be professionally trained and familiar with the characteristics and emergency treatment methods of 1% 2C6-dibromoethane, so as to ensure the safety of storage and transportation.