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1-Bromo-2-Methylpropane

Qiji Chemical

1-Bromo-2-Methylpropane
Specifications

HS Code

280868

Name 1-Bromo-2-Methylpropane
Molecular Formula C4H9Br
Molar Mass 137.018 g/mol
Appearance Colorless liquid
Odor Characteristic odor
Density 1.261 g/cm³
Boiling Point 91 - 92 °C
Melting Point -117 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in many organic solvents like ethanol, ether
Flash Point 18 °C
Vapor Pressure 7.3 kPa (20 °C)
Packing & Storage
Packing 100 mL of 1 - Bromo - 2 - Methylpropane in a tightly - sealed glass bottle.
Storage 1 - Bromo - 2 - methylpropane should be stored in a cool, well - ventilated area away from heat sources and ignition sources. It should be kept in a tightly - sealed container to prevent vapors from escaping. Store it separately from oxidizing agents and strong bases. Since it is flammable, ensure storage areas comply with fire - safety regulations, and keep appropriate fire - fighting equipment nearby.
Shipping 1 - Bromo - 2 - Methylpropane is shipped in tightly sealed, corrosion - resistant containers. It's transported in accordance with hazardous chemical regulations, ensuring proper handling to prevent spills and exposure during transit.
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1-Bromo-2-Methylpropane 1-Bromo-2-Methylpropane
General Information
Historical Development
1 - Bromo - 2 - Methylpropane is also an organic compound. Its historical development can be traced back to the past. At the beginning, the sages of chemistry explored the secrets of organic matter, but their understanding of compounds was still shallow. And technology has gradually advanced, and research has deepened. After repeated experiments, scholars have analyzed its structure and properties. From the simple method of the past to the precise technique of today, the understanding of 1 - Bromo - 2 - Methylpropane is becoming more and more complete. Preparation in the past was difficult and small, but now the process is advanced and the yield can be increased. This compound is gradually showing its use in the field of organic synthesis and other fields. Its historical evolution is really a corner of the development of chemistry, witnessing the rise of human understanding of matter.
Product Overview
1 - Bromo - 2 - Methylpropane, an organic halogenated hydrocarbon. It is a colorless and transparent liquid with a special odor.
This compound contains bromine atoms and methyl groups in its molecular structure, and is active in nature. In the field of organic synthesis, it has a wide range of uses. It can be used as an alkylating agent to participate in nucleophilic substitution reactions and introduce specific groups.
Its preparation method is often obtained by substituting the corresponding alcohol with hydrobromic acid. During the reaction, a suitable temperature and catalyst are required to promote the reaction.
In industry and scientific research, 1 - Bromo - 2 - Methylpropane is an important raw material for the research and production of organic chemistry because it can derive many organic compounds.
Physical & Chemical Properties
1 - Bromo - 2 - Methylpropane is an organic compound, and its physicochemical properties are particularly important. Looking at its physical properties, at room temperature, this substance is in a liquid state, with a specific boiling point and melting point. The boiling point is related to its gasification temperature, and the melting point is related to its solidification conditions. Its density is also one of its characteristics, which is related to the space occupied in a specific environment and the relationship between mass.
When it comes to chemical properties, the bromine atom in 1 - Bromo - 2 - Methylpropane is quite active. It can participate in nucleophilic substitution reactions. Because the bromine atom is easy to leave, the molecule is electrophilic and can react with many nucleophilic reagents. And under suitable conditions, the elimination reaction can occur to remove hydrogen bromide and form olefins. This is determined by the molecular structure of the compound, which is the basis for applications in organic synthesis and other fields.
Technical Specifications & Labeling
Today there are 1 - Bromo - 2 - Methylpropane products, and its technical specifications and labeling (commodity parameters) are very important. Looking at this product, the technical specifications should indicate its purity geometry, and the impurity content should be carefully checked. If there are too many impurities, it will affect its quality and use.
In terms of labeling, the name "1 - Bromo - 2 - Methylpropane" should be clearly marked to prevent confusion. Its physical properties, such as color, state, smell, etc., should also be clearly indicated. The main points of chemical properties, such as stability, reactivity, etc., are also indispensable.
In the commodity parameters, packaging specifications, storage conditions, etc. should be detailed. Proper storage can ensure product quality. In this way, the product's technical specifications and labels are complete, which is beneficial to users and conducive to smooth market circulation.
Preparation Method
To prepare 1 - Bromo - 2 - Methylpropane, the raw materials, production process, reaction steps and catalytic mechanism are as follows.
First take isobutanol as the main raw material, with hydrobromic acid. In the reactor, mix isobutanol and hydrobromic acid in an appropriate ratio, and add an appropriate amount of sulfuric acid as a catalyst. This is a nucleophilic substitution reaction. Under the catalysis of sulfuric acid, the hydroxyl group of isobutanol is protonated to enhance its departure. In hydrobromic acid, bromine ions attack nucleophilic, and the hydroxyl group leaves. After a series of reaction steps, 1 - Bromo - 2 - Methylpropane is formed.
The reaction process needs to be controlled at a certain temperature to maintain the reaction rate and yield. Pure 1-Bromo-2-Methylpropane is obtained by separation and purification, such as distillation and extraction. This preparation method can effectively produce the target product through specific raw materials and steps through the catalytic mechanism.
Chemical Reactions & Modifications
1 - Bromo - 2 - Methylpropane is an important compound in organic chemistry. The study of its chemical reaction and modification is of great significance in the field of chemistry.
Looking at its chemical reaction, in the nucleophilic substitution reaction, the bromine atom acts as a leaving group and is easily replaced by many nucleophilic reagents. If it reacts with hydroxide ions in an alkaline environment, 2 - methyl - 1 - propanol will be formed. This reaction process follows the SN2 or SN1 mechanism and depends on the reaction conditions.
On modification, through specific chemical reactions, new functional groups can be introduced into its molecular structure to change its physical and chemical properties. For example, an addition reaction with olefins expands the carbon chain, which in turn affects its boiling point and solubility. In-depth research on the chemical reaction and modification of 1-Bromo-2-Methylpropane will help to develop new synthesis methods, prepare more valuable organic compounds, and promote the continuous progress of the field of organic chemistry.
Synonyms & Product Names
1 - Bromo - 2 - Methylpropane, this thing is also a regular thing in the chemical world. Its synonymous name also exists. It is common to cover the field of chemical industry, with more than one thing.
The ancient books of Guanfu, although there is no exact record of this thing, are deduced from the principles of today's chemistry, which shows its characteristics. In the chemical industry, the names vary, either according to its structure or according to its nature.
1 - Bromo - 2 - Methylpropane, which is also called by others, such as isobutyl bromide. Although the names are different, they are actually the same thing. In the chemical industry, this thing is used as a raw material or as a medium, and it has a wide range of uses. The difference in names is to facilitate the identification and use of all workers. It is very important for the industry to know the name of this thing synonymous with the name of the commodity, so that its characteristics can be understood and its use can be followed.
Safety & Operational Standards
1 - Bromo - 2 - Methylpropane is also an organic compound. Its preparation and use are related to safety and operating standards, and should not be careless.
When preparing, all raw materials and reagents must be taken according to the quantity and measured accurately. The utensils must be clean and dry to prevent impurities from mixing in and damaging the reaction. The temperature and duration of the reaction must be strictly controlled. If the degree of heating is too high, the reactants may decompose or cause side reactions; if it is too low, the reaction will be slow or even stagnant.
In the operation room, ventilation must be good. The gas of this compound may be irritating, and if it accumulates, it will be harmful to people. And it is flammable, and near fire is dangerous. Therefore, the source of fire should be kept away, and fire-extinguishing equipment must also be kept on hand.
When taking it, gloves, goggles and other protective objects are indispensable. If you accidentally touch the body, rinse it with plenty of water quickly; if it gets into your eyes, you need to seek medical attention immediately.
When storing, it should be placed in a cool, dry and ventilated place. Seal the device to prevent it from volatilizing and leaking. When separated from oxidants, strong alkalis, etc., to avoid chemical reactions and cause dangerous things.
During the handling process, handle it with care and do not damage the container. If there is a leak, quickly evacuate the personnel and strictly prohibit fire. Small leaks can be removed by adsorption of sand and other substances; large leaks require professional means.
In conclusion, the preparation, use, storage and handling of 1-Bromo-2-Methylpropane should be carried out in accordance with strict safety and operating practices.
Application Area
1 - Bromo - 2 - Methylpropane is an organic compound, which is widely used in many fields. Its application scope is the first in the field of organic synthesis. It can be used as a key intermediate, through nucleophilic substitution reaction, and many nucleophilic reagents, such as alcohols, amines, mercaptan, etc., to prepare various organic compounds. For example, by reacting with alcohols, ether compounds can be formed, which is an important reaction step in organic synthesis and is of great significance for the construction of complex organic molecular structures.
Furthermore, it has important applications in the field of medicinal chemistry. Due to its structural properties, it can be used as a starting material for the synthesis of specific drugs, modified by a series of chemical reactions to obtain compounds with specific pharmacological activities, providing a key basis for drug development.
In addition, in the field of materials science, 1 - Bromo - 2 - Methylpropane can be involved in the preparation of functional materials. By polymerizing or reacting with other monomers, materials are endowed with unique properties, such as improved material solubility and thermal stability, which contribute greatly to the development of materials science.
Research & Development
Yu Taste is dedicated to the research of 1 - Bromo - 2 - Methylpropane. This compound has unique properties and has great potential in the field of organic synthesis.
Begin to study its structure in detail, understand its bonding, explore the order of atomic arrangement, and know the relationship between its reactivity. Then, study its synthesis method, try various paths, hoping to prepare efficient and pure. Or change the reaction conditions, adjust the temperature and pressure, and observe its effect on the yield; or easy catalyst, observe its effect on the reaction rate and product purity.
During this period, many problems are also encountered. If the reaction selectivity is not good, impurities are difficult to remove. However, after unremitting research, consulting classics, and discussing with colleagues, we finally have a solution.
After long-term efforts, I have a little experience in the preparation and properties of 1-Bromo-2-Methylpropane. Although this research has a small success, the road ahead is still long. In the future, we should continue to improve, hoping to expand its application in industrial production and scientific research, and promote its development and contribute to its development.
Toxicity Research
Chemical refinement in modern times requires the study of toxicants. In today's view 1 - Bromo - 2 - Methylpropane, the study of its toxicity is crucial.
Chemical substances have many characteristics, and toxicity is hidden in them. 1 - Bromo - 2 - Methylpropane, or the danger of skin and breathing. Touch its substance, fear of causing skin diseases, redness, swelling and pain; inhale its gas, injure the lungs and various organs.
The study of toxicity is not done overnight. All kinds of experiments are needed to test its nature. Try it before animals, observe its reaction, analyze its physiological changes. More explore its dispersion in the environment, and its transformation with other substances.
Scholars should be cautious and clear about its harm, so as to avoid its risks and make chemical substances useful but not harmful to the public. With the aim of fine research, it is a blessing for the world to ensure people's safety and beauty.
Future Prospects
In the field of chemistry, the future prospect of 1 - Bromo - 2 - Methylpropane is interesting. Although its properties are known today, there are still unknowns that need to be explored urgently.
Looking at its reaction mechanism, it may open up new paths in the road of organic synthesis. Its unique structure may form the basis of new compounds, adding new possibilities for the pharmaceutical, materials and other industries.
In the future, it is hoped that its reaction conditions can be more refined, the process can be optimized, and the cost can be reduced and the efficiency can be increased. And hope that it can emerge in emerging fields, such as green chemistry, new energy material preparation, etc. Make this compound contribute to scientific and technological progress and human well-being, lead a new journey of chemical exploration, and draw a bright chapter for future development.
Frequently Asked Questions
What are the chemical properties of 1-Bromo-2-Methylpropane?
1-Bromo-2-methylpropane is an organic compound. It has the common properties of halogenated hydrocarbons. This substance is active and can exhibit unique chemical properties in a variety of reactions.
First, nucleophilic substitution reaction. Due to the strong electronegativity of bromine atoms, polar bonds are formed with connected carbon atoms, making carbon atoms partially positive and vulnerable to attack by nucleophiles. When encountering hydroxyl negative ions (such as sodium hydroxide aqueous solution), bromine atoms will be replaced by hydroxyl groups to produce 2-methyl-1-propanol. During the reaction, hydroxyl negative ions provide a pair of electrons to attack the carbon atoms connected to bromine, and bromine leaves with a pair of electrons.
Second, elimination of the reaction is also an important property. Under the action of alcohol solution and strong base (such as potassium hydroxide alcohol solution), 1-bromo-2-methylpropane is prone to elimination reaction. The bromine atom and the hydrogen atom on the adjacent carbon atom are removed in the form of hydrogen bromide under the action of alkali to form a carbon-carbon double bond and produce 2-methylpropene. This reaction requires appropriate temperature and strong base conditions to promote intramolecular atom rearrangement.
Third, because of its halogen-containing atoms, it can participate in the preparation of organometallic compounds. Reacting with magnesium in anhydrous ether can generate Grignard reagents, which are extremely critical in organic synthesis and can react with carbonyl compounds and other substances to grow carbon chains and build complex organic molecular structures.
Fourth, 1-bromo-2-methylpropane is relatively stable and can be stored at room temperature and pressure without specific reagents and conditions. In case of open flames and hot topics, it may cause combustion and explosion. Because of its flammability, safety must be paid attention to when using and storing.
1-bromo-2-methylpropane has active chemical properties due to the presence of bromine atoms. Nucleophilic substitution, elimination and participation in the preparation of organometallic compounds make it widely used in the field of organic synthesis. However, it is necessary to pay attention to safety when using it and operate according to specifications.
What are the common applications of 1-Bromo-2-Methylpropane in organic synthesis?
1-Bromo-2-methylpropane is widely used in organic synthesis.
First, in nucleophilic substitution reactions, this compound often plays a key role. Because bromine atoms are active, they are easily replaced by nucleophiles. For example, under the action of alcohols and bases, anions of alcohols, as nucleophiles, can replace bromine atoms to generate corresponding ether compounds. This process is like a clever "atom transposition game". Nucleophiles, with their own attraction to the nucleus, precisely squeeze out bromine atoms and occupy their positions, thus building new organic molecular structures. In the synthesis of methyl isopropyl ether, the negative ion of alcohol is used to attack the bromine atom of 1-bromo-2-methylpropane nucleophilically to achieve the synthesis of ether.
Second, in the elimination reaction, 1-bromo-2-methylpropane also has an important role. In a strong alkali environment, it will undergo an elimination reaction, and the bromine atom will be removed together with the hydrogen atom on the adjacent carbon atom to form a carbon-carbon double bond and form an olefin. It is like a "slimming" inside the molecule, getting rid of some atoms and building a more unsaturated structure. For example, under the action of sodium ethanol, 1-bromo-2-methylpropane will be converted into 2-methylpropene. This olefin is an important intermediate in organic synthesis and can further participate in many reactions, such as addition to hydrogen halides, and can generate different halogenated hydrocarbons, which greatly enriches the path of organic synthesis.
Third, in the field of preparing Grignard reagents, 1-bromo-2-methylpropane has an extraordinary effect. It reacts with magnesium in anhydrous ether and other solvents to form Grignard reagents. Grignard reagents are active in nature and are like "generalists" in organic synthesis. They can react with many carbonyl-containing compounds, such as aldides, ketones, esters, etc., to form new carbon-carbon bonds. This is like a magical "building block" for building a skeleton for organic molecules. With the help of Grignard reagents and carbonyl compounds, complex and diverse organic molecular structures can be constructed, providing an effective way for the synthesis of various alcohols, which is of great significance in the fields of drug synthesis and total synthesis of natural products.
What are the preparation methods of 1-Bromo-2-Methylpropane?
1-Bromo-2-methylpropane, also known as isobutyl bromide, can be prepared in several ways.
First, isobutanol and hydrobromic acid are co-heated. Isobutanol has the common properties of alcohol, hydrobromic acid is a strong acid. Mixing the two, heating promotes its reaction. The reaction formula is:\ (CH_3) _2CHCH_2OH + HBr\ stackrel {\ Delta} {\ longrightarrow} (CH_3) _2CHCH_2Br + H_2O\). In this reaction, the hydroxyl group of the alcohol is replaced by a bromine atom to form 1-bromo-2-methylpropane and water. During the reaction, the temperature needs to be controlled appropriately, and either too high or too low will affect the yield. High temperature, side reactions, such as dehydration of isobutanol into alkenes; low temperature, slow reaction rate, time-consuming.
Second, isobutylene and hydrogen bromide are added. Isobutylene contains carbon-carbon double bonds, which are active as ethylenes. Hydrogen of hydrogen bromide is connected to one end of the carbon of the double bond, and bromine is connected to the other end of the carbon. According to the Markov rule, the main product is 1-bromo-2-methylpropane. The reaction formula is:\ (CH_3) _2C = CH_2 + HBr\ longrightarrow (CH_3) _2CHCH_2Br\). This reaction does not need to be heated. Under normal temperature and pressure, with an appropriate catalyst, it can be carried out smoothly, and the operation is convenient. The yield can also be observed.
Third, replace 2-methylpropane with bromine under light or high temperature. 2-methylpropane is an alkane and undergoes a radical substitution reaction with bromine. Light or high temperature splits bromine molecules into bromine radicals, which take hydrogen atoms from 2-methylpropane to form 1-bromo-2-methylpropane and hydrogen bromide. However, the selectivity of this reaction is poor. Due to the different hydrogen atom activities of 2-methylpropane, a variety of bromide products will be generated, and the separation and purification are more complex, so the practical application is limited.
What are the physical properties of 1-Bromo-2-Methylpropane?
1-Bromo-2-methylpropane is an organic compound with unique physical properties. It is a colorless to light yellow transparent liquid at room temperature and pressure, and has a special smell. The boiling point of this substance is about 91.5 ° C, the density is nearly 0.866 g/cm ³, which is lighter than water, and it is difficult to dissolve in water. It can be miscible with many organic solvents such as ethanol and ether.
Looking at its appearance, it is colorless to light yellow and transparent, just like a clear spring, and it is like a shimmering light in the morning mist, slightly yellow, crystal clear, in the container, like smart water, gently shaking, light and shadow flowing. Smell its smell, the special smell is tangy, not like the fragrance of flowers, nor the bad smell of rancidity, but it is unique and impressive.
When talking about the boiling point, the value of 91.5 ° C means that when the temperature rises to this point, 1-bromo-2-methylpropane will change from liquid to gaseous, like a phoenix nirvana, the change of shape, witness the properties of matter. Its density is 0.866 g/cm ³, lighter than water. If it is placed in one place with water, it is like oil floating on the water, with distinct layers, independent of each other, and contrasting each other. As for solubility, it is difficult to dissolve in water, but it blends with organic solvents such as ethanol and ether, as if in different chemical worlds, finding their own confidants, blending with each other, regardless of each other.
1-Bromo-2-Methylpropane what are the precautions during storage and transportation?
1-Bromo-2-methylpropane is an organic compound. During storage and transportation, many matters must be paid attention to.
First heavy packaging. The packaging must be tightly sealed to prevent leakage. The packaging materials used must be resistant to the corrosion of the compound and can effectively resist external physical damage, such as strong glass bottles, metal drums, etc., supplemented by sealing gaskets to ensure that there are no gaps and leaks.
The second is the storage environment. It should be placed in a cool and ventilated place, away from fire and heat sources. This compound is flammable, and it is easy to cause combustion and explosion in case of open flames and hot topics. Therefore, the temperature of the storage place should not be too high, and the ventilation must be good to disperse the steam that may accumulate.
Furthermore, avoid mixing with oxidants, strong bases and other substances. 1-Bromo-2-methylpropane is prone to violent oxidation reactions when it encounters oxidants, and may also cause chemical reactions when it encounters strong bases, resulting in damage to stability. Therefore, it should be stored separately and kept at a certain distance.
When transporting, caution is also required. Transportation vehicles must be equipped with corresponding fire fighting equipment and leakage emergency treatment equipment. During driving, violent actions such as sudden braking and sharp turns should be avoided to prevent package damage. Transportation personnel should also be familiar with the characteristics of the compound and emergency treatment methods to ensure safe transportation.