Qiji Chemical
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1-Bromopropane

Qiji Chemical

1-Bromopropane
Specifications

HS Code

187076

Chemical Formula C3H7Br
Molar Mass 122.99 g/mol
Appearance Colorless liquid
Odor Sweet, chloroform - like odor
Density 1.3537 g/cm³ at 20 °C
Boiling Point 71 - 72 °C
Melting Point -110.8 °C
Solubility In Water Slightly soluble, 0.37 g/100 mL at 20 °C
Solubility In Organic Solvents Soluble in ethanol, diethyl ether, chloroform, etc.
Vapor Pressure 46 mmHg at 25 °C
Flash Point -1 °C (closed cup)
Refractive Index 1.4343 at 20 °C
Packing & Storage
Packing 1 - Bromopropane packaged in 5 - liter containers for chemical use.
Storage 1 - Bromopropane should be stored in a cool, well - ventilated area, away from heat and ignition sources. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, acids, and bases. Follow local safety regulations to ensure proper storage and minimize potential fire, explosion, or chemical reaction risks.
Shipping 1 - Bromopropane is shipped in well - sealed, appropriate containers compliant with hazardous chemical regulations. It's transported by methods ensuring safety, avoiding spillage and exposure during transit.
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1-Bromopropane 1-Bromopropane
General Information
Historical Development
1 - Bromopropane is an important member of the field of organic compounds. Back in the past, since the dawn of organic chemistry, scholars have focused on the study of halogenated hydrocarbons. 1 - Bromopropane, as a member of the halogenated alkane family, its preparation method has evolved over the years.
In the early days, organic chemists tried to obtain it through complex and inefficient reaction paths. At that time, due to technical and cognitive limitations, the yield was low and there were many impurities. However, with the improvement of chemical theory and the improvement of experimental methods, better methods gradually emerged. Taking the reaction of propanol and hydrobromic acid as an example, the precise control of conditions has greatly improved the yield.
In modern times, the growth of industrial demand has promoted the innovation of the preparation process of 1 - Bromopropane. The integration of green chemistry concepts has made the reaction more environmentally friendly and efficient. The road to preparation in the past was full of thorns, but now it has entered a smooth path. 1-Bromopropane plays a key role in many fields of chemical production, and its future development will also be closely linked to scientific and technological progress, with promising prospects.
Product Overview
1 - Bromopropane, Chinese name 1 - bromopropane, is a kind of organic compound. Its properties are colorless to light yellow liquid, with a special odor, soluble in organic solvents such as alcohols and ethers, and insoluble in water.
This compound has a wide range of uses in the field of organic synthesis, often used as an alkylating agent, participating in many chemical reactions. In the chemical industry, it is a key raw material for the preparation of a variety of fine chemicals. In the pharmaceutical industry, it is also an indispensable intermediate for the synthesis of specific drugs.
The method of preparing 1 - Bromopropane is commonly obtained by substituting n-propanol with hydrobromic acid. The reaction process requires a suitable temperature and catalyst to promote the smooth progress of the reaction.
However, 1 - Bromopropane is toxic and volatile. When using it, attention should be paid to safety protection. Operate in a well-ventilated environment to avoid inhaling its steam into the human body to prevent damage to health. At the same time, its waste should also be properly disposed of to avoid polluting the environment.
Physical & Chemical Properties
1 - Bromopropane is an organic compound. Its physical and chemical properties can be investigated quite a bit. Looking at its physical properties, under room temperature, it is a colorless liquid with a special odor. Its boiling point is about 71-72 degrees Celsius, the density is slightly lighter than that of water, and it is insoluble in water. However, it can be miscible with many organic solvents, such as ethanol and ether.
In terms of its chemical properties, the bromine atom in 1 - Bromopropane is quite active. It can be substituted with nucleophiles. If it encounters an aqueous solution of sodium hydroxide, the hydroxyl group replaces the bromine atom to form n-propanol; if it encounters potassium hydroxide in an alcoholic solution, the elimination reaction occurs to obtain propylene. It is widely used in the field of organic synthesis and can be used as a raw material for the preparation of many organic compounds, assisting chemists in achieving a variety of synthesis paths. It is of great value in chemical research and industrial production.
Technical Specifications & Labeling
1 - Bromopropane is also a chemical product. Its technical specification (commodity quality) is to be determined.
If the husband wants to make this product, he will follow the technical specification of the fine. The quality of raw materials must be correct, the proportion should be matched, and the quality should be refined. The reverse quality, such as the degree and quality, are all well-controlled, and the best quality is 1 - Bromopropane.
And the quality (commodity quality) should not be ignored. On the package, clearly add its name, specify the formula C, H, Br, and the value of the content and quality. And warn its danger, such as flammability, irritation, etc., so that the user can understand it to ensure safety. In this way, the combination of technology and quality (commodity quality) can ensure that the product of 1-Bromopropane can be preserved and used.
Preparation Method
1 - Bromopropane is also an organic compound. The preparation method is related to the raw material and production process, reaction steps and catalytic mechanism.
When preparing, propane and bromine are often used as raw materials. First, propane is subjected to free radical substitution reaction with bromine under the condition of light or heating. In this reaction step, the hydrogen atom in the propane molecule is attacked by bromine free radicals, and one hydrogen atom is replaced by a bromine atom to generate 1 - Bromopropane.
During the reaction process, it is necessary to pay attention to the control of light intensity or heating temperature, which is the key to affecting the reaction rate and product purity. And the catalytic mechanism is also important. Appropriate catalysts, such as peroxides, can be added to promote the generation of free radicals and speed up the reaction process. In this way, through the delicate regulation of raw materials, steps and catalysis, pure 1-Bromopropane can be obtained.
Chemical Reactions & Modifications
1 - Bromopropane is also an organic compound. In the field of chemistry, the reaction and modification are worth exploring. In the past, the synthesis methods were many complicated, and the yield was not improved.
Looking at the reaction, nucleophilic substitutions are common. Halogen atoms are active and often attacked by nucleophilic reagents. However, the traditional reaction conditions are harsh, requiring high temperature and strong alkali, and side reactions are frequent, resulting in impure products.
Today's chemists are trying their best to find a way to modify them. With new catalysts, the reaction conditions are gradually milder and the yield is also improved. If you choose a high-efficiency metal catalyst, you can direct the reaction and reduce by-products.
Under the concept of green chemistry, we are exploring environmentally friendly solvents and processes. The reaction system using water as a solvent has emerged, which not only reduces pollution, but also is in line with sustainable development. 1 - The chemical reaction and modification of Bromopropane are advancing along the path of refinement, exploring new paths for organic synthesis.
Synonyms & Product Names
1 - Bromopropane is also a chemical product. Its name is the trade name, which can be investigated. This compound, also known as n-propyl bromide. The name of n-propyl bromide, because there is n-propyl in its chemical name.
This product is also known by its name. However, its main trade names are often associated with its chemical name. The clarity of the trade name is important for the research, production and use of this product. Only by understanding its name can it be known for its properties and functions. So that both the person and the person can know it by its name. 1 - Bromopropane, and there is a risk of confusion. Therefore, inquiry 1 - Bromopropane's trade name is one of the important factors in the study of transformation.
Safety & Operational Standards
1-Bromopropane, or 1-bromopropane, is a chemical commonly used in organic synthesis. It is necessary to be cautious about its safety and operating standards.
For storage, it should be placed in a cool and ventilated warehouse. Keep away from fire and heat sources to prevent accidents. It should be stored separately from oxidants, alkalis, etc., and should not be mixed. The storage area should be equipped with suitable materials to contain leaks to prevent leakage. It can be properly handled in time to avoid greater harm.
When operating, be sure to strictly follow the specifications. It is recommended that the operator wear a self-priming filter gas mask (half mask), wear chemical safety glasses, wear anti-poison infiltration work clothes, and wear rubber oil-resistant gloves to protect their own safety in an all-round way. The operation should be carried out in a place with local ventilation or full ventilation to avoid steam leakage into the air of the workplace. And keep away from fire and heat sources. Smoking is strictly prohibited in the workplace. Use explosion-proof ventilation systems and equipment to prevent the formation of explosive mixtures between its vapor and air. When filling, the flow rate should be controlled, and there should be a grounding device to prevent the accumulation of static electricity from causing danger. During handling, it should be handled lightly to prevent damage to packaging and containers.
If a leak unfortunately occurs, quickly evacuate the personnel from the leaked contaminated area to the safe area, and isolate and strictly restrict access. To cut off the source of fire, emergency personnel should wear self-contained positive pressure breathing apparatus and anti-toxic clothing. Cut off the source of leakage as much as possible to prevent it from flowing into restricted spaces such as sewers and flood ditches. In the case of a small amount of leakage, it can be adsorbed or absorbed by sand or other non-combustible materials, or it can be scrubbed with an emulsion made of non-combustible dispersant, and the lotion is diluted and placed in the wastewater system. When there is a large amount of leakage, build a dike or dig a pit to contain it, cover it with foam to reduce steam disasters, and then transfer it to a tanker or a special collector with an explosion-proof pump for recycling or transportation to a waste treatment site for disposal.
Only by strictly adhering to the above safety and operating standards can the safety of the use of 1-bromopropane be
Application Area
1 - Bromopropane is also an organic compound. Its application field is quite wide, and it is often a key raw material in the process of chemical synthesis. If specific ethers are prepared, they can be reacted with alcohols appropriately to obtain ethers with different structures, which makes remarkable contributions in the field of organic solvents.
In the field of pharmaceutical synthesis, it also has its own shadow. Through a series of reactions, it can help synthesize some pharmaceutical intermediates with specific curative effects, laying the foundation for pharmaceutical research and development.
In addition, in the surface treatment of materials, 1 - Bromopropane may participate in reactions to improve the properties of the surface of materials, such as enhancing its hydrophilicity and enhancing the binding force with other substances. From this perspective, 1 - Bromopropane has important value in many application fields and is an indispensable substance for chemical research.
Research & Development
Today's research on 1 - Bromopropane is related to research and progress. We investigate its properties in detail to clarify its state in various reactions.
After many experiments, we know the method of its preparation, or from propane and bromine, according to the conditions of light, the substitution should be used to obtain this substance. And in the field of organic synthesis, 1 - Bromopropane is often an important agent, which can be used as nucleophilic substitution with many reagents to form various organic compounds.
Looking at its development, with the progress of chemical industry, the preparation method is becoming more and more exquisite, and the yield is also rising. And its application field is gradually widening, and it is useful in medicine, materials and other industries. We should continue to study it, explore its potential, and promote its better development for the benefit of the world.
Toxicity Research
Smell 1 - Bromopropane, in our chemical research, its toxicity research is crucial. Investigate it in detail today.
After various experimental investigations, 1 - Bromopropane has a certain toxicity. It may be breathed into the body, spread between the lungs and organs, and then affect the function of the organs. Looking at the state of the experimental rats, after inhaling this substance, they often appear restless and short of breath, and for a long time, there are signs of organ damage.
And it is also harmful when it comes into contact with the skin. It can cause skin redness, swelling, itching, and even ulceration. If it is not accidentally entered into the eyes, it will sting unbearably, or damage the vision.
It can be seen that the toxicity of 1 - Bromopropane cannot be underestimated. During research and application, it is necessary to exercise extreme caution and adhere to protective regulations to prevent harm, ensure the health of researchers, and protect the peace of the environment.
Future Prospects
1 - Bromopropane, organic halide is also used. In today's world, its application is quite wide, and it is useful in synthetic chemistry, pharmaceutical and chemical fields.
Looking at its future prospects, science and technology are new, and research and development is unremitting. Chemists may be able to find new paths and expand their application domains. In material science, it may become a raw material for new materials, and the material can be added with specificity.
And environmental protection needs to be cut off day by day, 1 - The preparation of Bromopropane or a cleaner method can reduce its pollution of the ring. In pharmaceutical research and development, it may help to become a new agent, cure diseases, and benefit the world. We should look forward to it, and expect it to shine in the future and make contributions to human well-being.
Frequently Asked Questions
What are the main uses of Bromopropane?
1-Bromopropane is an organic compound with a wide range of uses. It is mainly used in organic synthesis and can be used as a raw material for the synthesis of many important organic compounds. For example, in the field of drug synthesis, it can be converted into intermediates with specific pharmacological activities through specific chemical reactions, and then drugs for treating diseases can be synthesized.
In the preparation of fine chemical products, 1-bromopropane also plays a key role. It can be used to prepare fine chemicals such as fragrances and dyes. For example, in fragrance synthesis, through a series of reactions, compounds with unique aromas can be generated, providing a rich choice for the fragrance industry.
In addition, 1-bromopropane is often used in alkylation reactions. In the process of organic synthesis, alkyl groups can be introduced into the molecules of other compounds to change their chemical properties and structures, so as to prepare organic compounds that meet different needs.
Furthermore, in the preparation of some organometallic compounds, 1-bromopropane is often used as a starting material. By reacting with metal reagents, organometallic intermediates are formed, laying the foundation for subsequent organic synthesis reactions and promoting the development and progress of organic synthesis chemistry. In short, 1-bromopropane has indispensable uses in many fields such as organic synthesis and fine chemistry.
What are the physical properties of Bromopropane?
1-Bromopropane is an organic compound. It is a colorless and transparent liquid at room temperature and pressure. It has a special odor and a slightly sweet taste. The boiling point of 1-bromopropane is about 71 ° C, and the melting point is about -110 ° C. The density of this substance is greater than that of water, about 1.35g/cm ³. It is insoluble in water, but it can be miscible with most organic solvents such as ethanol, ether, and chloroform.
Its vapor is heavier than air and can spread at a lower place to a considerable distance. In case of ignition, it will catch fire and backfire. The vapor pressure of 1-bromopropane is about 13.3 kPa at 25 ° C, and the flash point is quite low, about -1 ° C. It is a flammable liquid. It can cause combustion and explosion in case of open flame and high heat, and can react strongly with oxidants.
In addition, 1-bromopropane has certain toxicity. After inhalation, ingestion or absorption through the skin, it can cause damage to the body. It has irritating effects on the eyes, skin, mucous membranes and respiratory tract. After exposure, it may cause symptoms such as burning sensation, cough, wheezing, laryngitis, shortness of breath, headache, nausea and vomiting. Therefore, when using and storing 1-bromopropane, it is necessary to pay attention to safety and take protective measures to prevent accidents such as fire, explosion and poisoning.
What are the chemical properties of Bromopropane?
1-Bromopropane is also an organic compound. It is active and can be seen in many chemical reactions.
The chemical properties of this substance are first discussed in its substitution reaction. In 1-bromopropane, the bromine atom is highly active and easily replaced by nucleophiles. For example, when co-heated with an aqueous solution of sodium hydroxide, the bromine atom is replaced by a hydroxyl group to form 1-propanol. The reason for the reaction is that the negative hydroxyl ion acts as a nucleophile to attack the carbon atom connected to the bromine atom, and the bromine ion leaves to form a substituted product.
Furthermore, 1-bromopropane can be eliminated. If co-heated with an alcohol solution of potassium hydroxide, the hydrogen bromide is removed from the molecule to form propylene. In this process, by the action of alkali, the bromine atom and the hydrogen atom on the adjacent carbon atom are removed in the form of hydrogen bromide, forming carbon-carbon double bonds in the molecule.
In addition, 1-bromopropane can interact with metal magnesium to form Grignard reagents. Grignard reagents are extremely active and have a wide range of uses in organic synthesis. They can react with many reagents such as carbonyl compounds to form carbon-carbon bonds, providing an important means for organic synthesis.
1-bromopropane is chemically active and exhibits its characteristics in reactions such as substitution, elimination, and Grignard reagent generation. It plays an important role in the field of organic chemistry and lays the foundation for the synthesis of many organic compounds.
What are the preparation methods of Bromopropane?
The preparation method of 1-bromopropane, as well as organic compounds, is quite important. The main preparation methods are listed below:
First, it is prepared from n-propanol and hydrobromic acid. Under appropriate conditions, such as heating and catalyzed by sulfuric acid, the hydroxyl group of n-propanol reacts with the bromine atom of hydrobromic acid. The hydroxyl group in the n-propanol molecule is replaced by the bromine atom, so 1-bromopropane is obtained, and water is formed at the same time. The chemical equation for this reaction is: $CH_ {3} CH_ {2} CH_ {2} OH + HBr\ xrightarrow [] {H_ {2} SO_ {4},\ Delta} CH_ {3} CH_ {2} CH_ {2} Br + H_ {2} O $. Sulfuric acid here not only promotes the reaction, but also absorbs the water generated by the reaction, promoting the reaction to move in the direction of generating 1-bromopropane.
Second, it is prepared by free radical addition reaction of propylene and hydrogen bromide. In the presence of peroxide, propylene reacts with hydrogen bromide. The double bond of propylene is opened, and the hydrogen and bromine atoms of hydrogen bromide are added to the carbon atoms at both ends of the double bond. Because the reaction follows the anti-Markov rule, bromine atoms are mainly added to the double-bonded carbon atoms containing more hydrogen, so 1-bromopropane is formed. The chemical equation of this reaction is: $CH_ {3} CH = CH_ {2} + HBr\ xrightarrow [] {peroxide} CH_ {3} CH_ {2} CH_ {2} Br $. Peroxide is the initiator in this reaction, which prompts the reaction to proceed according to the mechanism of free radical addition.
Third, it is prepared by the reaction of propanol and phosphorus tribromide. Propanol is mixed with phosphorus tribromide and a substitution reaction occurs. The bromine atom of phosphorus tribromide replaces the hydroxyl group of propanol to form 1-bromopropane, and phosphoric acid is formed at the same time. The chemical equation for this reaction is: $3CH_ {3} CH_ {2} CH_ {2} OH + PBr_ {3}\ longrightarrow 3CH_ {3} CH_ {2} CH_ {2} Br + H_ {3} PO_ {3} $. The reaction conditions are relatively mild and the yield is quite high.
What are the precautions for using Bromopropane?
1-Bromopropane is an organic compound, and all precautions must be kept in mind during use.
First, it is related to safety protection. This substance is irritating and can cause damage to the eyes, respiratory tract and skin. Therefore, when using, it is necessary to wear suitable protective equipment, such as protective glasses, which can protect the eyes from its splashing damage; wear a gas mask to prevent inhalation of its volatile gases and damage to the respiratory tract; wear protective clothing to protect the skin.
Second, pay attention to the operating environment. It should be operated in a well-ventilated place. Because 1-bromopropane is volatile, good ventilation can make the volatile gases dissipate in time, reduce the concentration in the air, and avoid risks such as combustion and explosion caused by its accumulation. Fireworks are strictly prohibited in the operating place. This substance is flammable. In case of open flames and hot topics, it is very easy to burn and explode. Therefore, there should be a clear no-fire logo in the operation room.
Third, about storage points. It should be stored in a cool and ventilated warehouse, away from fire and heat sources. The warehouse temperature should not exceed 30 ° C. It should be stored separately from oxidants, acids and alkalis, and should not be mixed to prevent reactions. The storage place should be equipped with leakage emergency treatment equipment and suitable containment materials.
Fourth, if there is a leakage situation. In the event of a small amount of leakage, it can be absorbed by inert materials such as sand and vermiculite, put into an airtight container, and disposed of according to regulations. A large number of leaks need to be built embankments or excavated to contain them, covered with foam to reduce their volatilization, and then transferred to a tanker or special collector with an explosion-proof pump, recycled or transported to a waste treatment site for disposal.
In short, when using 1-bromopropane, it is necessary to strictly follow safety procedures and operate with caution to ensure personal safety and environmental safety.