Qiji Chemical
Products

2 Bromopropane

Qiji Chemical

Specifications

HS Code

766915

Chemical Formula C3H7Br
Molar Mass 122.99 g/mol
Appearance Colorless to pale - yellow liquid
Odor Characteristic, sweet - pungent odor
Density 1.31 g/cm³ at 20 °C
Boiling Point 59 - 60 °C
Melting Point -112 °C
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in many organic solvents like ethanol, ether
Vapor Pressure 40.5 kPa at 20 °C
Flash Point -20 °C
Refractive Index 1.429 at 20 °C
Packing & Storage
Packing 100 - gram bottle of 2 - Bromopropane, well - sealed for chemical storage.
Storage 2 - Bromopropane should be stored in a cool, well - ventilated area, away from heat, sparks, and open flames as it is flammable. It should be kept in a tightly - sealed container, preferably made of a material resistant to corrosion. Store it separately from oxidizing agents and strong bases to prevent chemical reactions. Ensure proper labeling for easy identification and safety.
Shipping 2 - Bromopropane is shipped in tightly - sealed containers, usually made of corrosion - resistant materials. It's transported under controlled conditions to prevent spills, as it's a flammable and potentially hazardous chemical.
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General Information
Frequently Asked Questions
2 - What are the main uses of Bromopropane?
2 + -Bromopropane, also known as isobromopropane, is an important raw material for organic synthesis. It has a wide range of uses and plays a key role in many fields.
First, in the field of pharmaceutical synthesis, 2 + -bromopropane is often used as an intermediate. It can be converted into various pharmaceutical components through many chemical reactions. For example, in the synthesis of certain anti-infective drugs, 2 + -bromopropane can participate in specific reaction steps, providing key chemical fragments for the construction of drug active structures. Through carefully designed reaction routes, it can be combined with other compounds to gradually build complex drug molecular structures and help develop effective therapeutic drugs.
Second, in the manufacture of pesticides, 2 + -bromopropane also plays an important role. It can be used as a starting material or intermediate for the synthesis of pesticides, and is used to prepare pesticide products with specific insecticidal, herbicidal or bactericidal properties. With its unique chemical structure, it can react with other pesticide-related chemicals to generate pesticide components with high biological activity, which helps to improve crop yield and ensure agricultural production.
Third, in the field of organic material synthesis, 2 + -bromopropane can be used to synthesize special organic compounds, which may have unique physical or chemical properties and are suitable for the manufacture of high-performance materials. For example, when synthesizing certain organic materials with specific solubility, thermal stability or optical properties, 2 + -bromopropane can be used as a key structural unit to participate in the construction of materials, providing a new material basis for the development of materials science.
In addition, 2 + -bromopropane is still a commonly used reagent in the study of organic synthesis chemistry. Researchers use it to conduct various reaction exploration and methodological research, providing an important experimental tool for the development of new organic synthesis methods and technologies, and promoting the continuous development of the field of organic chemistry.
2 - What are the physical properties of Bromopropane?
2 + -bromopropane, its physical properties are as follows:
This substance is a colorless and transparent liquid at room temperature, with a special odor and a slightly sweet taste. Its density is lighter than that of water, about 0.8617g/cm ³, and it can float on water. The boiling point is moderate, at 59-60 ° C, at this temperature, the liquid will quickly transform into a gaseous state. The melting point is relatively low, at -117 ° C. Below this temperature, 2 + -bromopropane will solidify into a solid state.
2 + -bromopropane is insoluble in water, because the water molecules are connected by hydrogen bonds and have a tight structure, while 2 + -bromopropane is a non-polar molecule, and the force between it and the water molecules is weak, so it is difficult to dissolve. However, it can be miscible with organic solvents such as ethanol and ether in any ratio. Because these organic solvents and 2 + -bromopropane are both non-polar or weakly polar molecules, they can be well mixed with each other according to the principle of "similar miscibility".
Its refractive index is 1.3772. This optical property causes light to be refracted at a specific angle when passing through 2 + -bromopropane. This property is very important in optical analysis and identification of this substance.
In addition, 2 + -bromopropane is highly volatile. At room temperature and pressure, it will quickly evaporate from liquid to gaseous state and diffuse in the air. Its vapor is heavier than air and is easy to accumulate at low places, so it is necessary to pay attention to prevention.
2 - What are the chemical properties of Bromopropane
2 + -Bromopropane, which is a colorless and transparent liquid with a pungent odor. In terms of chemical properties, it is quite active.
First, the nucleophilic substitution reaction is its important characteristic. Because of its high activity of bromine atoms in the molecule, it is easy to be replaced by nucleophilic reagents. In the case of aqueous solution of sodium hydroxide, bromine atoms will be replaced by hydroxyl groups to generate 2-propanol. The process of this reaction is that the nucleophilic reagent hydroxyl groups attack the carbon atoms connected to the bromine atoms, causing the bromine ions to leave.
Second, the elimination reaction is also its significant property. When 2-bromopropane is heated with an alcohol solution of potassium hydroxide, an elimination reaction occurs to form propylene. In this process, the bromine atom is removed from the hydrogen atom on the adjacent carbon atom in the form of hydrogen bromide, and then a carbon-carbon double bond is formed.
Third, 2-bromopropane can participate in the reaction of organometallic compounds. For example, with magnesium in an anhydrous ether environment, Grignard reagents can be formed. Grignard reagents are extremely active and can react with many carbonyl-containing compounds, such as aldose and ketone. They are widely used in the field of organic synthesis and can build carbon-carbon bonds to help synthesize more complex organic molecules.
Fourth, 2-bromopropane can also undergo free radical substitution reactions. Under the condition of light or initiator, the hydrogen atom in the molecule can be replaced by the halogen atom to form different halogenated products. The mechanism of this reaction involves the generation and transfer of free radicals, which can be used to introduce specific functional groups in organic synthesis.
2 - What is the preparation method of Bromopropane?
To make 2-bromopropane, there are two common methods. First, the addition of propylene and hydrogen bromide. Propylene, carbon-containing double-bonded alkenes. When hydrogen bromide meets, according to the Markov rule, hydrogen is added to the double-bonded carbon with more hydrogen, and bromine is added to the double-bonded carbon with less hydrogen, resulting in 2-bromopropane. Its chemical equation is: $CH_2 = CHCH_3 + HBr\ longrightarrow CH_3CHBrCH_3 $. This reaction conditions are mild, easy to operate, and the yield is quite high.
Second, 2-propanol is reacted with hydrobromic acid. 2-Propanol is a secondary alcohol, co-heated with hydrobromic acid, and the hydroxyl group of the alcohol is replaced by a bromine atom to obtain 2-bromopropane. Its chemical equation is: $CH_3CH (OH) CH_3 + HBr\ xrightarrow {\ Delta} CH_3CHBrCH_3 + H_2O $. This reaction requires heating, and sulfuric acid is often used as a catalyst to promote the reaction. However, during the reaction process, there may be side reactions, such as intermolecular dehydration to ether, etc., so it is necessary to control the reaction conditions to increase the yield of 2-bromopropane.
2 - What are the precautions for using Bromopropane?
2 + -Bromopropane, organic compounds are also used, and many precautions must be observed during use.
First, this material is flammable, and it is easy to burn in case of open flames and hot topics. Therefore, where it is used, when fireworks are strictly prohibited, and it is kept away from heat sources, it should be properly stored in a cool and ventilated place. It must not be placed in a place with high temperature and direct sunlight to prevent the risk of fire.
Second, 2 + -bromopropane is harmful to the human body. Its vapor or fog can irritate the eyes and upper respiratory tract, and if inhaled too much, it may cause headaches, dizziness, nausea, vomiting, etc. If it accidentally touches the skin, or causes dermatitis; if it splashes into the eyes, it will be especially harmful. When using, be well protected. In front of protective clothing, wear protective gloves, wear safety goggles, and ensure that the operating environment is well ventilated. It is best to work in a fume hood to avoid inhaling harmful vapors.
Third, 2 + -bromopropane is chemically active and easy to react with many substances. When using, avoid co-storage and mixing with strong oxidants, strong bases, etc., to prevent violent reactions and cause danger. After the operation is completed, the residue and waste should not be discarded at will. When properly disposed of in accordance with relevant regulations, to prevent environmental pollution.
Fourth, the user must be familiar with its characteristics and emergency treatment methods. If a leak occurs accidentally, the personnel in the contaminated area should be evacuated to a safe place and quarantined. Emergency responders need to wear self-contained positive pressure breathing apparatus, wear anti-toxic clothing, and do not come into direct contact with leaks. Small leaks can be absorbed by inert materials such as sand and vermiculite; if there are large leaks, they should build embankments or dig holes to contain them, cover them with foam to reduce steam disasters, and then transfer them to a tanker or special collector with an explosion-proof pump for recycling or transportation to a waste treatment site for disposal. If any person is poisoned or injured, immediately send them to the hospital for treatment. In this way, the use of 2 + -bromopropane is guaranteed to be safe.