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2-Bromopropane

Qiji Chemical

2-Bromopropane
Specifications

HS Code

998315

Name 2-Bromopropane
Chemical Formula C3H7Br
Molar Mass 122.99 g/mol
Appearance Colorless liquid
Odor Sweet, chloroform - like odor
Density 1.31 g/cm³ at 20 °C
Boiling Point 59.4 - 60.4 °C
Melting Point -89 °C
Solubility In Water Slightly soluble
Vapor Pressure 31.6 kPa at 20 °C
Flash Point -15 °C
Packing & Storage
Packing 100 mL of 2 - Bromopropane packaged in a tightly - sealed glass bottle.
Storage 2 - Bromopropane should be stored in a cool, well - ventilated area, away from heat, sparks, and open flames as it is flammable. Keep it in a tightly closed container to prevent vapor leakage. Store it separately from oxidizing agents and strong bases to avoid potential reactions. The storage area should be dry to prevent hydrolysis of the compound.
Shipping 2 - Bromopropane is shipped in tightly - sealed, corrosion - resistant containers. It's classified as a hazardous substance, so strict regulations govern its transport to prevent spills and ensure safety during transit.
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2-Bromopropane 2-Bromopropane
General Information
Historical Development
In the past, organic chemistry was flourishing, and various sages made great efforts to study it, and the secrets of compounds gradually emerged in the world. 2 - Bromopropane was also noticed at that time. At first, scholars explored its structure and properties, but they were still in ignorance.
With the passage of time, science and technology have advanced, and the understanding of 2 - Bromopropane has deepened. Know the method of its preparation, or by the addition of propylene and hydrogen bromide, or by other routes. It is used in the field of organic synthesis, and it can be used as an intermediate to help other compounds be born.
Looking at its historical development, from the beginning of ignorance to the clarification of its sexual use, it is the work of countless chemists. This compound is like a star in the evolution of chemistry. Although it is small, it is indispensable. It pushes the boat of organic chemistry to break through the waves in the sea of knowledge and sail towards the unknown new territory.
Product Overview
2 - Bromopropane Product Overview
2 - Bromopropane, also known as isopropyl bromide, is a colorless and transparent liquid with a special odor. Its preparation is often obtained by the reaction of isopropanol and hydrobromic acid under the catalysis of sulfuric acid.
This compound is widely used in the field of organic synthesis and is an important alkylation reagent. It can be substituted with a variety of nucleophiles, such as reacting with sodium alcohol to form ethers, reacting with sodium cyanide to form nitriles, and introducing specific functional groups to organic molecules. In pharmaceutical synthesis, it is a key raw material for the preparation of some pharmaceutical intermediates, which is of great significance to promote the process of drug research and development; in the field of pesticides, it also participates in the synthesis of various pesticide active ingredients, helping agricultural pest control
2 - Bromopropane boiling point is moderate, 60 - 61 ℃, density of about 1.31 g/cm ³, slightly soluble in water, miscible in ethanol, ether, acetone and other organic solvents, relatively stable properties, but in case of open flame, hot topic easy to burn, use should strictly follow the safety specifications, in cool, well ventilated storage.
Physical & Chemical Properties
2 - Bromopropane is also an organic compound. Its physical and chemical properties are quite specific. Looking at its physical properties, it is a colorless and transparent liquid at room temperature, volatile and pungent. Its boiling point is about 59 ° C, the density is slightly larger than that of water, and it is difficult to dissolve in water, but it can be miscible with most organic solvents.
In terms of its chemical properties, the bromine atom in 2 - Bromopropane is highly active and prone to substitution reactions. If it is co-heated with an aqueous solution of sodium hydroxide, the bromine atom can be replaced by a hydroxyl group to form 2 - propanol. When it is co-heated with sodium hydroxide in an alcoholic solution, an elimination reaction occurs to form propylene. This is due to the characteristics of the carbon-bromine bond in its structure, which has strong polarity and bromine atoms are easy to leave, thus triggering various chemical reactions and is widely used in the field of organic synthesis.
Technical Specifications & Labeling
There is now a way to make 2-Bromopropane, and its process specifications and identification (product parameters) are the key. If you want to make this product, you must first select the raw materials, and the one with pure quality and stable properties is better. When reacting, control it at a suitable temperature, check its heat, and make sure it is just right.
As for the logo, the name of the declaration is "2-Bromopropane", which details the physical and chemical properties, such as color and taste, melting point, density geometry, so that the viewer can see at a glance. Repeat its danger to warn the world and prevent accidental contact from causing harm. The product parameters should not be ignored, the purity geometry, and the number of impurities should be detailed. In this way, we can obtain the excellent 2-Bromopropane, and people can make good use of this item according to its process specifications and labels to achieve everything.
Preparation Method
The key to the preparation of 2-Bromopropane is the raw material and the production process. Isopropane and hydrogen bromide are often used as raw materials, and the two are combined. The reaction step is to make isopropane and sulfuric acid co-heat to obtain isopropyl hydrogen sulfate, followed by sodium bromide and the reaction to produce 2-Bromopropane.
Its catalytic mechanism, sulfuric acid acts as a catalyst in the first step of the reaction to accelerate the conversion of isopropane. When isopropyl hydrogen sulfate encounters sodium bromide, bromine ions nucleophilic replace hydrogen sulfate, which prompts the formation of the product. During operation, the temperature and the ratio of reactants need to be carefully adjusted, so that high purity 2-Bromopropane can be obtained, and the yield is considerable.
Chemical Reactions & Modifications
Recent research 2 - The chemical properties of Bromopropane, I have some experience, so here.
2 - Bromopropane, the generation is also. Its chemical properties are specific, and in the context of sexual behavior, nuclear substitution is often reversed. The nucleus can attack its carbon bromide and bromide to generate alcohol. This reaction is still to be considered.
As for the chemical properties, 2 - Bromopropane is active due to its carbon bromide content. However, its qualitative nature is also affected by the surrounding group. To improve its chemical properties, you can start to integrate the chemical properties, such as changing the degree, force, or catalysis. It can also be modified and functionally increased to improve its anti-reactive properties. In this way, it may be more effective in chemical synthesis.
Synonyms & Product Names
2 - Bromopropane is the same trade name as Bromopropane. 2 - Bromopropane, also known as propyl bromide. It is an important chemical compound in the chemical field.
The name of propyl bromide, which contains propyl in its body, and the phase of bromine atoms. This name is also commonly used in chemical literature and communication in the chemical industry.
As for the trade name, there is also a specific name in the circulation of the chemical industry. However, its naming may depend on the strategy of the family or the characteristics of the product.
Due to its special chemical properties, this compound has a wide range of uses in the synthesis and other fields. It can be used for multiplication and reaction, such as nuclear substitution, etc., and is an important raw material for many chemical substances.
>, 2 - Bromopropane and its congener, propyl bromide, as well as different trade names, all play an important role in the development of various technologies, promoting the development of chemical research and production.
Safety & Operational Standards
2 - Bromopropane Product Safety and Practice
#1. Introduction
2 - Bromopropane is a chemical commonly used in chemical research. It is essential for our chemical researchers to be familiar with its safety and practice practices.
#2. Safety Matters
1. ** Toxicity Prevention **: 2 - Bromopropane is toxic and can cause physical damage if inhaled, ingested or absorbed through the skin. During the experiment, be sure to wear suitable protective equipment, such as gas masks, protective gloves and goggles, to prevent contact.
2. ** Explosion hazard **: This substance is flammable. In case of open flame and hot topic, there is a risk of combustion and explosion. In the laboratory, it should be kept away from fire and heat sources, and well ventilated to prevent the formation of explosive mixed gases.
#III. Operating specifications
1. ** Access operation **: When taking 2 - Bromopropane, it should be carried out in a fume hood. Use clean and dry utensils, accurately measure the required amount, and avoid spilling. If there is spilling, it should be immediately covered with inert materials such as sand and vermiculite for absorption and properly disposed of.
2. ** Reaction operation **: For chemical reactions involving 2 - Bromopropane, the reaction conditions, such as temperature, pressure and ratio of reactants, need to be strictly controlled. According to the reaction characteristics, choose the appropriate reaction device to ensure the safe and smooth progress of the reaction. During the reaction process, closely observe the reaction phenomenon. If there is any abnormality, take corresponding measures immediately.
3. ** Storage requirements **: 2 - Bromopropane should be stored in a cool and ventilated warehouse. Keep away from fire and heat sources, and the storage temperature should not exceed 30 ° C. Keep the container sealed. It should be stored separately from oxidants, acids and alkalis, and avoid mixed storage. Equip with the corresponding variety and quantity of fire equipment. The storage area should be equipped with leakage emergency treatment equipment and suitable containment materials.
#4. Emergency treatment
1. ** Leak emergency **: In the event of a 2 - Bromopropane leak, quickly evacuate personnel from the spill-contaminated area to a safe area and isolate them. Strictly restrict access. Cut off the source of fire. It is recommended that emergency personnel wear self-contained positive pressure breathing apparatus and anti-toxic clothing. Cut off the source of leakage as much as possible. Prevent it from flowing into restricted spaces such as sewers and drainage ditches. Small leaks: Absorb with sand, vermiculite or other inert materials. Large leaks: Construct embankments or dig pits for containment. Cover with foam to reduce vapor disasters. Use explosion-proof pumps to transfer to tankers or special collectors, recycle or transport to waste disposal sites for disposal.
2. ** Poisoning first aid **: If inhaled inadvertently, quickly leave the scene to a fresh place of air. Keep the respiratory tract unobstructed. If breathing difficulties, give oxygen. If breathing stops, perform artificial respiration immediately and seek medical attention. If ingested, drink enough warm water, induce vomiting, seek medical attention. Contact skin, remove contaminated clothing, rinse skin thoroughly with soapy water and water. Contact eyes, lift eyelids, rinse with flowing water or normal saline, and seek medical attention.
Our chemical researchers must strictly follow the above safety and operating practices when using 2-Bromopropane to ensure their own safety and ensure the smooth conduct of the experiment.
Application Area
2-Bromopropane, or 2-bromopropane, has a wide range of uses. In the field of organic synthesis, it is often a key raw material. Taking the preparation of specific ether compounds as an example, 2-bromopropane and alcohols can be catalyzed by bases to generate corresponding ethers through nucleophilic substitution reactions. These ethers are quite valuable in solvents and organic synthesis intermediates.
In the field of medicinal chemistry, 2-bromopropane also plays an important role. In the synthesis path of some drugs, 2-bromopropane needs to introduce specific chemical groups to achieve the construction and modification of drug molecular structures, and then endow drugs with specific physiological activities.
In the field of materials science, it can participate in the preparation of polymers with special properties. By reacting with monomers containing unsaturated bonds, its structural units can be introduced into the polymer backbone, thereby changing the physical and chemical properties of the polymer, such as solubility, thermal stability, etc., to meet the needs of different material application scenarios.
Research & Development
In recent years, Yu has devoted himself to the research of organic compounds, especially in the field of 2-Bromopropane. This compound has an exquisite structure and is widely used in the chemical industry.
At the beginning, analyzing its preparation method, there were many defects in the traditional way, the yield was not ideal, and the side reactions were frequent. Yu then thought hard and looked for an optimization strategy. After months of experiments, adjusting the reaction factors, such as temperature, pressure, and catalyst selection, he finally got an improved method. Under the new approach, the yield of 2-Bromopropane was significantly improved, and the by-products were also greatly reduced.
Then, explore its application. In the way of pharmaceutical synthesis, it is a key intermediate and can help to form a variety of special agents. In the field of material research and development, it can give materials unique properties. I also work with colleagues to research and expand its use to a wider range.
Looking forward to the future, the research and development of 2-Bromopropane should make great progress. Our scientific researchers must be diligent and diligent, tap its potential, and do our best for the prosperity of the chemical industry and the benefit of people's livelihood.
Toxicity Research
Taste and smell chemical substances, related to people's livelihood, but the toxicity of them cannot be ignored. Today, as far as 2-Bromopropane products are concerned, this is an organic halide, which is active.
Observing the opinions of various families in the past, organic halide may have potential harm. 2 - Bromopropane is inhaled through skin contact, breathing, and may enter the human body and damage the viscera.
Those who have tried it on white mice have been exposed to the environment containing 2-Bromopropane. For a long time, they have been seen to move slowly and look sluggish. It is also analyzed that the various organs in its body, the genus of liver and kidney, are all abnormal, or caused by toxicity.
And this substance is not easy to degrade in the environment, accumulates over time, or causes soil and water pollution. It is our chemical researchers who should be careful and careful to study the toxicity of 2-Bromopropane products in detail, and strive to seek advantages and avoid disadvantages, so as to protect the common people and the safety of the world.
Future Prospects
I try to study 2 - Bromopropane this chemical thing. Observe its properties, understand the principles of its reactions, and always think about its future development.
In today's world, science and technology are changing day by day, and the field of chemistry is following suit. 2 - Bromopropane is used in organic synthesis and has a wide range of uses. It can be a raw material for many compounds, contributing to the prosperity of medicine, materials and other industries.
My heart hopes that in the future, the research of 2 - Bromopropane will go to a higher level. Or find a better synthesis method, reduce its cost, increase its yield; or explore new applications, expand its field, so that it can bring more benefits to the world. And hope to reduce its impact on the environment, in line with the concept of green chemistry. In this way, 2-Bromopropane will surely shine in the future, contributing to the life of our generation and the development of the world.
Frequently Asked Questions
What are the main uses of Bromopropane?
2-Bromopropane is also an organic compound. It has a wide range of uses and is used in various fields such as industry and medicine.
In industry, it is often a raw material for organic synthesis. First, propylene can be prepared by elimination reaction. This reaction is carried out in an alcohol solution of a strong base, 2-bromopropane removes hydrogen bromide to obtain propylene. Propylene, an important organic chemical raw material, can also be used to prepare polypropylene, acrylonitrile and other polymer materials, and can also be used to synthesize a variety of organic compounds. Second, 2-bromopropane can participate in nucleophilic substitution reactions. For example, when reacted with sodium alcohol, ether compounds can be formed. This ether compound is useful in organic solvents, reaction media, etc.
In the field of medicine, 2-bromopropane also has its role. Because of its chemical activity, it can be used as a pharmaceutical intermediate. Through a series of chemical reactions, it is converted into compounds with specific pharmacological activities, and then used in the synthesis of drugs.
In addition, 2-bromopropane is also a commonly used reagent in the study of organic synthesis chemistry. Chemists can deeply understand the mechanism of organic reactions, expand the methods and strategies of organic synthesis, and provide ideas and foundations for the creation of new organic compounds through the exploration and study of its reactions. In short, 2-bromopropane plays an important role in many fields due to its unique chemical properties.
What are the physical properties of Bromopropane?
2-Bromopropane is also an organic compound. It has unique physical properties. Looking at its properties, it is a colorless and transparent liquid at room temperature, and has an ether-like odor.
In terms of its density, it is heavier than water, about 1.31 g/cm ³. This property makes 2-bromopropane settle at the bottom when mixed with water.
As for the boiling point, it is about 59.4 ° C. When heated to this temperature, 2-bromopropane gradually changes from liquid to gaseous, and gasification occurs. Its melting point is -89 ° C, and it will condense into a solid state at low temperatures.
The solubility of 2-bromopropane is also an important physical property. It is slightly soluble in water, but it can be miscible with organic solvents such as alcohols, ethers, and benzene. Because the molecular structure of 2-bromopropane has a similar polarity to that of organic solvents, it can be miscible with each other according to the principle of "similar miscibility".
In addition, 2-bromopropane is volatile and can evaporate slowly in air. Its vapor and air can form an explosive mixture. In case of open flame and high heat, it can cause combustion and explosion. When using, take precautions to ensure safety.
2. What are the chemical properties of Bromopropane?
2-Bromopropane is also an organic compound. It has the general properties of halogenated hydrocarbons, and its chemical properties are quite active, and it can participate in many chemical reactions.
First, nucleophilic substitution reactions are also. The halogen atom bromine is quite exoteric, and it is easy to be replaced by nucleophilic reagents when encountering nucleophilic reagents. If it is co-heated with an aqueous solution of sodium hydroxide, the bromine atom is replaced by a hydroxyl group to obtain 2-propanol. The reaction formula is: (CH
Second, eliminate the reaction. If 2-bromopropane is co-heated with an alcohol solution of sodium hydroxide, the hydrogen bromide is removed to form propylene. The reaction formula is: (CH
Third, when it interacts with metallic magnesium, it can form Grignard's reagent. In an anhydrous ether environment, 2-bromopropane reacts with magnesium to obtain isopropyl magnesium bromide, that is, (CH
CHBr + Mg $\ xrightarrow [] {anhydrous ether} $ (CH
CHMgBr. Grignard reagents are widely used and can react with carbonyl compounds to form carbon-carbon bonds, which is important in the field of organic synthesis.
Fourth, they can also react with reagents such as sodium alcohol, and follow the mechanism of nucleophilic substitution or elimination reaction. The products vary depending on the reaction conditions.
2-bromopropane is a common raw material in the organic synthesis industry due to its active chemical properties. Through various reactions, a variety of organic compounds can be prepared, which is of great significance to the development of organic chemistry and chemical production.
What are the synthesis methods of 2-Bromopropane?
To make 2-bromopropane, there are two methods. First, the addition of propylene and hydrogen bromide. Propylene, with unsaturated double bonds, hydrogen and bromine in hydrogen bromide, each with its own properties, interact with the double bond of propylene. Hydrogen, with a tendency to be positively charged, first combines with one end of the carbon of the double bond, so that the other end of the carbon is positively charged, and the negative bromine ion is attached. According to the Markov rule, hydrogen is added to the carbon containing more hydrogen, and bromine is added to the carbon containing less hydrogen. This addition method can obtain 2-bromopropane. The reaction is as follows: $CH_3CH = CH_2 + HBr\ stackrel {appropriate conditions} {\ longrightarrow} CH_3CHBrCH_3 $.
Second, react with hydrobromic acid with 2-propanol. The hydroxyl group of 2-propanol has the activity of nucleophilic substitution. The bromine ion in hydrobromic acid is a nucleophilic reagent, attacking the carbon connected to the hydroxyl group of 2-propanol, and the hydroxyl group combines hydrogen protons to form water and leave to obtain 2-bromopropane. The reaction formula is: $CH_3CH (OH) CH_3 + HBr\ stackrel {appropriate conditions} {\ longrightarrow} CH_3CHBrCH_3 + H_2O $. These two methods have their own lengths, depending on the ease of availability of raw materials, the difficulty of reaction, and the purity of the product.
What to pay attention to when storing and transporting Bromopropane
2-Bromopropane is an organic compound that is flammable and toxic. When storing and transporting, special attention should be paid to the following matters:
First, the storage place must be cool and ventilated. Because it is volatile when heated, in a high temperature environment, it will not only increase the risk of leakage, but also the volatile vapor is mixed with air, which is easy to form an explosive mixture. In case of open flame and high heat, it can cause combustion and explosion. Therefore, it should be kept away from fire and heat sources, and the storage temperature should not exceed 30 ° C.
Second, it needs to be stored separately from oxidants, acids, alkalis, etc., and should not be mixed. 2-Bromopropane in contact with oxidants may cause violent chemical reactions, or even explosions; in contact with acid and alkali, or reactions such as hydrolysis may occur, causing it to deteriorate.
Third, the storage container must be well sealed. To prevent 2-bromopropane from leaking and volatilizing, one is to avoid pollution to the environment, and the other is to prevent its vapor from accumulating in the air and causing safety accidents. The container material used should be able to withstand the corrosion of 2-bromopropane, and containers such as steel or specific plastic materials are commonly used.
Fourth, when transporting, make sure that the container does not leak, collapse, fall, or damage. The transportation vehicle should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. It is best to transport in the morning and evening in summer to avoid high temperature periods. During transportation, it is necessary to prevent exposure to the sun, rain and high temperature. When transporting by road, it is necessary to drive according to the specified route and do not stop in residential areas and densely populated areas.
Fifth, operators need to undergo special training and strictly abide by the operating procedures. It is recommended that operators wear self-priming filter gas masks (half masks), chemical safety glasses, anti-poison penetration overalls, and rubber oil-resistant gloves to avoid direct contact and ensure personal safety.