Bromoform

Qiji Chemical

Specifications

HS Code	154423
Chemical Formula	CHBr3
Molar Mass	252.73 g/mol
Appearance	Colorless to pale - yellow, dense, heavy liquid with a sweet odor
Density	2.89 g/cm³ (at 25 °C)
Melting Point	7.8 °C
Boiling Point	149.5 °C
Solubility In Water	Slightly soluble (0.3 g/L at 25 °C)
Vapor Pressure	1.33 kPa at 48.4 °C
Refractive Index	1.595 (20 °C)
Flash Point	Non - flammable

Packing & Storage

Packing	100 - gram bottle of bromoform, tightly sealed in chemical - resistant packaging.
Storage	Bromoform should be stored in a cool, well - ventilated area away from heat and ignition sources. It should be kept in a tightly - sealed container, preferably made of materials resistant to its corrosive nature, like glass or certain plastics. Store it separately from oxidizing agents and incompatible substances to prevent dangerous reactions.
Shipping	Bromoform, a hazardous chemical, is shipped in accordance with strict regulations. It's typically transported in well - sealed, approved containers to prevent leakage, ensuring safety during transit by land, sea, or air.

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General Information

Historical Development

Bromoform is also a chemical substance. Its development in history has been considerable. In the past, chemists first got involved in this substance, studying its properties and methods of preparation. At first, it was difficult to obtain, and it was only occasionally obtained in the laboratory. However, as time went by, the deeper the research, the more refined the method was, and the production also increased.
At that time, bromoform was not widely used, but was mostly used for academic inquiry. Later, with the wide range of knowledge, it emerged in various fields of medicine and industry. Doctors observed its ability to sterilize and prevent corrosion, and used it in pharmaceuticals. In industry, it is also a raw material and solvent, and it gradually becomes more and more important. Looking at its history, it has been hidden in the laboratory and widely used by people. On the way to development, it has witnessed the progress of chemistry and the change of human consciousness.

Product Overview

Bromoform is also a chemical substance. It is a colorless and heavy liquid with a specific odor and taste. It is relatively stable under normal conditions, but gradually decomposes when exposed to light, releasing toxic hydrogen bromide.
Bromoform has a wide range of uses and is often an important raw material in the field of organic synthesis. It can be used in the preparation of various drugs and fine chemicals. In laboratories, it is also often used as a solvent because it has good solubility to a variety of organic compounds.
However, bromoform is toxic to a certain extent. If it is inadvertently inhaled, ingested or absorbed through the skin, it can endanger human health. Therefore, strict safety procedures must be followed when using and storing to ensure the safety of experimenters and the environment. In industrial production and applications, it is also necessary to properly dispose of it to prevent it from causing pollution to the environment.

Physical & Chemical Properties

Bromoform is a chemical substance. It has unique physical and chemical properties. Looking at its physical properties, it is a colorless heavy liquid at room temperature, and it smells like chloroform. Its density is greater than that of water, and it can sink to the bottom. The boiling point is quite high, about 150.8 ° C, and it is difficult to volatilize when heated.
In terms of its chemical properties, bromoform has certain stability, but it can also participate in many chemical reactions under specific conditions. Its molecular structure contains bromine atoms, which gives it special chemical activity. It can react with lye to generate corresponding salts and other products. In the field of organic synthesis, bromoform is often used as an important raw material to help chemists construct a variety of organic compounds, making great contributions to chemical research and production.

Technical Specifications & Labeling

"Bromoform Technical Specifications and Labeling (Commodity Parameters) "
This bromoform is the key to its technical specifications and labeling. Bromoform, pure in color and clear in quality, should have a specific density, accurate to a certain value range, and the boiling point needs to be stable within a certain range, which is its important physical label.
Above purity, it must reach a very high level, and the impurity content is minimal before it can be qualified for commodity parameters. Its preparation techniques need to follow delicate procedures to ensure consistent quality.
In terms of labeling, when the name of "bromoform" is stated on the packaging, a clear warning label is attached to indicate its chemical properties and potential hazards. Mark the product parameters in detail, such as the proportion of ingredients, physical property data, etc., so that the user can see at a glance, in order to comply with safety and regulations, and use it in a suitable way.

Preparation Method

"On the Preparation Method of Bromoform"
If you want to make bromoform, the raw materials, production process, reaction steps and catalytic mechanism are all key.
The first raw materials can be ethanol, bromine and alkali. The production process is that ethanol reacts with bromine in the alkali environment. The reaction steps are as follows: When ethanol encounters bromine, it first forms an aldehyde bromide, which is then further brominated, and finally forms bromoform.
In the catalytic mechanism, alkali is crucial in the reaction and can accelerate the reaction process. The alkali liquid greatly increases the alpha-hydrogen activity of ethanol and is easily replaced by bromine. In this way, after multiple steps of substitution, bromoform is finally obtained. When preparing, it is necessary to control the temperature, the amount of bromine and the concentration of alkali to ensure the smooth reaction and obtain pure bromoform products.

Chemical Reactions & Modifications

If bromoform is used, it is also a good thing to be transformed. Its transformation and reverse properties are studied by people who want to be transformed. The inverse effects of bromoform, or substitution, or addition, and general transformation, are all in line with the transformation.
In the past, bromoform was used in a specific way, but its method may have the disadvantages of complexity, and the efficiency is not high. People think hard and seek ways to improve. With unremitting research, we have obtained exquisite methods, which has improved the efficiency of bromoform and made it more useful. Therefore, the improvement of the reverse of the chemical process is the key to promoting the chemical process.

Synonyms & Product Names

Bromoform, whose scientific name is tribromomethane, is also an organic compound. Its aliases include carbonyl bromide, trichloride bromide, etc. In the chemical industry, it has a wide range of uses.
This substance is a colorless heavy liquid with a special smell. In the chemical books of the past, there are also many related records. Although the name at that time may be different from today, the thing referred to is actually this substance.
It is often an important raw material in industrial production. Or used to synthesize some fine chemicals, or used as a solvent in specific chemical reactions. Although the name changes over time, its essence and use have many continuities. Many common names and trade names related to it, although expressed differently, all refer to this bromoform.

Safety & Operational Standards

"Bromoform Product Safety and Operation Specifications"
covers the research of chemistry, which is related to safety, and the rules of operation cannot be ignored. When discussing Bromoform, its safety and operation specifications should be detailed.
Bromoform is unique in nature. It is in a closed space, if it is heated or exposed to open fire, it may be dangerous. Therefore, it should be placed in a cool and well-ventilated place, away from fire and heat sources, and must not be mixed with oxidants to prevent unexpected changes.
When operating, it is necessary to have protective equipment. Such as wearing chemical safety glasses to prevent splashing into the eyes; wearing protective clothing to prevent it from harming the body and skin; wearing rubber gloves to keep both hands safe. In the operation room, ventilation equipment should be good to allow gas to escape and avoid accumulation.
When taking it, the action should be slow and do not spill it. If it is accidentally spilled, cover it with inert materials such as sand and vermiculite as soon as possible, collect it properly, and do not let it overflow. When cleaning, dispose of it according to regulations, and do not discard it at will.
Furthermore, those who come into contact with this object should be aware of first aid. If it touches the skin, rinse it with plenty of water as soon as possible; if it enters the eyes, rinse it with flowing water or normal saline immediately, and seek medical attention as soon as possible. If inhaled, leave the scene as soon as possible, go to a place with fresh air, give artificial respiration if necessary, and seek medical attention.
In short, all matters related to the safety and operation of Bromoform should be treated with caution and should not be ignored. Adhering to this standard will ensure the smooth research and the well-being of personnel.

Application Area

Bromoform is also a chemical substance. Its application field is quite broad. In the field of medicine, it was used as a sedative in the past, but now it is rarely used because of its toxicity.
In the industrial world, bromoform can be used as a solvent to help a variety of organic synthesis. In the laboratory, chemists use it to prepare specific compounds, which can make the reaction proceed as expected due to their unique chemical properties.
In analytical chemistry, bromoform can be used as a density liquid to separate substances of different densities. This function is based on its own relatively high density, which can make the substance stratified according to density, making it easy to study and extract. Although its application in chemical research and industrial production is not extensive, it is of indispensable value in specific situations, promoting many explorations and developments in the field of chemistry.

Research & Development

I have been studying bromoform for a long time. Bromoform is also a chemical substance with unique properties and a wide range of uses.
At the beginning, the method of its preparation was cumbersome. After repeated experiments, the process was improved to make its yield gradually increase. In the field of medicine, bromoform can be used as a sedative, but its dosage must be accurate, and a little poor, it will cause a lot of harm.
It can be used as a solvent to dissolve many substances and help industrial production processes run smoothly. And bromoform is also an important reagent in scientific research experiments, providing assistance for many studies.
I continue to study, hoping to expand the use of bromoform, improve its quality, and contribute to the academic and industrial circles. I hope that bromoform will bloom brighter in the future development and add luster to human well-being.

Toxicity Research

Taste the way of chemical industry, is related to the nature of all things. In today's discussion of Bromoform, the study of its toxicity is particularly important.
Bromoform is pure in color but different in taste, and may be useful in chemical industries. However, its toxicity cannot be ignored. In the past, Zhu Xian studied it, and found that its entry into the body can disturb the ability of the viscera. Entering through the skin and breathing, it gradually damages the liver and kidneys, causing perverse qi and blood. Looking at various experiments, rats touch it, hyperactive and uneasy, and the organs are diseased.
It is also considered in the environment, and there are also disadvantages. Scattered in water and soil, it harms living things. Aquatic things, when they encounter it, will suffer, or die or change, and the ecological balance will be chaotic because of it.
Therefore, when studying the toxicity of Bromoform, we should be cautious to explore the depth of its harm and find preventive measures to preserve the safety of life and the environment.

Future Prospects

Bromoform has been used in this world, but our generation of chemists is looking forward to its future development. Bromoform has unique characteristics and can be used in various fields of medicine and chemical industry.
In the future, science and technology are new, and bromoform may be used in the development of new drugs. Its bactericidal and antiseptic properties may lead to the development of better drugs to save people from illness. And in the chemical industry, or due to the characteristics of bromoform, it has spawned exquisite synthesis methods to create strange and novel materials to meet the needs of the time.
Although it is currently used in practice, we expect to explore the potential of bromoform in the future. Or it can optimize the production method, reduce its consumption, reduce its pollution, and make it more suitable for sustainability. At that time, bromoform will be in the curtain of the future, show its brilliance, add bricks and mortar to human well-being, and create a new chapter, living up to our expectations.

Frequently Asked Questions

What are the chemical properties of Bromoform?

For bromoform, the chemical formula is CHBr, which is an organic halide. Its properties are numbered and detailed below.
Bromoform is a colorless and heavy liquid with a sweet smell. Its boiling point is quite high, about 149.5 ° C, and its density is greater than that of water, which is 2.89 g/cm ³. This liquid is insoluble in water, but it is easily soluble in organic solvents such as alcohols, ethers, and chloroform.
In terms of its chemical properties, the carbon-bromine bond of bromoform has certain activity. In case of strong bases, it can dehalogenate. For example, in an alcohol solution of sodium hydroxide, bromoform can gradually remove bromine atoms and form products containing unsaturated bonds. And bromoform can be slowly decomposed under light or heat conditions to release hydrogen bromide.
Bromoform has a wide range of uses in the field of organic synthesis. It can be used as an intermediate for the preparation of organic compounds with specific structures. Because it contains bromine atoms, bromine atoms can be introduced into the target molecule by substitution reaction, which in turn affects the chemical and physical properties of the molecule.
Also bromoform was used occasionally in the field of medicine in the past, but in view of its toxicity and potential harm, it is rarely used today. In short, bromoform has unique chemical properties and has a specific position in the chemical industry and other fields. When using it, pay attention to its safety and impact on the environment.

What are the main uses of Bromoform?

Bromoform is an organic compound, which is widely used and has several important ways.
First, in the field of medicine, bromoform was used as an anesthetic in the past. At that time, medicine was not as developed as it is today. Bromoform could make patients gradually lose consciousness and cause temporary loss of pain, so it was used in surgery to help patients slightly reduce pain. However, with the evolution of medicine, because of its toxicity and possible adverse reactions, it was gradually replaced by better anesthetic drugs.
Second, in industry, bromoform is an important organic synthesis raw material. It can participate in the synthesis of many organic compounds, and by means of chemical changes, it can be turned into other fine chemicals. It has its own influence in many branches of the chemical industry, such as the synthesis of fragrances, dyes, etc., and helps various products to have unique properties and functions.
Third, in the field of analytical chemistry, bromoform is also useful. Because of its high density and other characteristics, it is often used as a medium for density layer centrifugation. By means of the different sedimentation rates of different substances in bromoform solutions, the separation and analysis of substances can be realized, helping scientists to explore the composition and structure of substances.
Fourth, bromoform is also used in agriculture. Once used as a soil fumigant, it can kill harmful bacteria, pests, and weed seeds in the soil, creating a good soil environment for crop growth and protecting crops from pests and diseases. However, it may have an impact on the environment, and its use today is also subject to many restrictions.

What is the impact of Bromoform on the environment?

Bromoform is also an organic halide. Its impact on the environment is worth exploring.
Bromoform is volatile and can enter the atmosphere. In the atmosphere, bromoform can participate in photochemical reactions and pose a potential threat to the ozone layer. With its bromine content, bromine atoms can catalyze ozone decomposition under specific conditions, causing ozone depletion, causing more ultraviolet rays to reach the surface, endangering organisms, increasing the risk of skin cancer, cataracts and other diseases, and affecting the balance of the ecosystem.
If bromine enters the water body, it will cause harm to the aquatic ecosystem. It can migrate and transform in water, affecting water quality. For aquatic organisms, bromoform may be toxic, interfering with their physiological functions, affecting their growth, reproduction and development. Such as inhibiting the photosynthesis of aquatic plants, reducing their productivity; causing abnormal behavior, physiological damage, or even death of aquatic animals. Long-term accumulation will change the structure and function of aquatic ecosystems and destroy biodiversity.
In the soil environment, bromoform may affect the activity and community structure of soil microorganisms. Soil microorganisms play a key role in the process of soil nutrient cycle and organic matter decomposition. The existence of bromoform may change the metabolic pathway of microorganisms, inhibit the growth of beneficial microorganisms, and affect the health and function of soil ecosystems.
And bromoform is difficult to degrade in the environment and is easy to bioaccumulate. Organisms ingest bromoform through the food chain, and the concentration is enriched with the increase of the food chain, which may eventually pose a threat to human health at the top of the food chain. From this perspective, bromoform has a wide and complex impact on the environment, and it is necessary to treat it with caution, strengthen monitoring and control, and reduce its harm to the ecological environment and human health.

What are the precautions for Bromoform during storage and transportation?

Bromoform is also an organic compound. During storage and transportation, it is necessary to pay attention to many matters to ensure its safety.
First, when storing, choose a cool and ventilated warehouse. Because of its volatility, high temperature or no ventilation, it is easy to cause the accumulation of bromoform steam, which not only increases the risk of fire, but also endangers human health. The temperature of the warehouse should be controlled within a specific range to prevent its volatilization from being intensified due to excessive temperature, or other adverse chemical reactions caused by sudden temperature changes.
Second, bromoform should be stored separately from oxidants and alkalis, and should not be mixed. Due to the active chemical properties of bromoform, it is easy to cause violent chemical reactions in case of oxidants, or cause combustion and explosion; in case of alkalis, it may also react, causing it to deteriorate, affecting the quality and performance.
Third, the storage container must be well sealed. Bromoform is volatile, and poor sealing will cause bromoform to escape, which will not only cause material loss, but also pollute the environment. Containers made of glass or metal are commonly used, and the integrity of the container should be checked regularly to prevent leakage.
Fourth, when transporting, it should be handled in accordance with the relevant regulations on hazardous chemicals. Transportation vehicles must have corresponding qualifications and protective measures, and drivers and escorts must also be professionally trained to be familiar with bromoform characteristics and emergency treatment methods. During transportation, ensure that the container is stable to avoid damage and leakage due to collision and vibration.
Fifth, whether it is stored or transported, it should be equipped with corresponding emergency treatment equipment and protective equipment. Such as fire extinguishers, adsorption materials, gas masks, etc. In the event of an accident such as leakage, measures can be taken quickly to reduce the harm.

What are the methods for preparing Bromoform?

Bromoform, that is, tribromomethane, has been prepared in ancient times. In the past, bromoform was prepared by ancient methods.
First, acetone is reacted with hypobromite. In this reaction, in an alkaline medium, the methyl group of the acetone molecule is attacked by the nucleophilic attack of the hypobromite salt, and after several steps of reaction, bromoform is finally obtained. The process should pay attention to the reaction temperature and the proportion of reactants. If the temperature is too high, the side reactions will increase; if the ratio is improper, the yield will be poor.
Second, ethanol and bromine can also be prepared under alkaline conditions. Ethanol is first oxidized to acetaldehyde, and then acetaldehyde is haloform with bromine. At the beginning of the reaction, ethanol is slowly converted to acetaldehyde, and then acetaldehyde and bromine react rapidly in an alkaline environment, and bromoform is gradually formed. In this process, the concentration of the base is quite critical. If the concentration is too high or too low, it will affect the reaction process and yield.
Third, it is prepared by haloform reaction. Select a suitable methyl ketone compound and react with halogen (bromine) in an alkaline solution. At the beginning of the reaction, halogen and methyl in methyl ketone are replaced, and polyhalides are gradually formed, and then under the action of alkali, the carbon-carbon bond is broken and bromoform is released. This approach requires high purity of the raw materials. The raw materials are not pure, which is easy to cause complex reactions, and the products are difficult to separate.
All kinds of preparation methods have advantages and disadvantages. When preparing, it is necessary to choose carefully according to the actual situation, such as the difficulty of obtaining raw materials and the requirements for product purity, in order to achieve the desired preparation effect.