What are the physical properties of Bromohexane?
Bromohexane is also an organic compound. Its physical properties can be described in many ways.
First of all, at room temperature, bromohexane is a colorless to light yellow transparent liquid, which looks clear. Its smell has a special aromatic smell. Although it is not strong and pungent, it also has its own taste.
As for its boiling point, it is about 154-158 ° C. At this temperature, bromohexane gradually converts from liquid to gaseous. The melting point is about -85 ° C. Below this temperature, bromohexane will condense into a solid state. The density of bromohexane is heavier than that of water, about 1.176g/cm ³, so if it is mixed with water, bromohexane will sink underwater. And it is difficult to dissolve in water, because bromohexane is a non-polar molecule, while water is a polar molecule. According to the principle of "similar miscibility", the two are insoluble. However, it is soluble in many organic solvents, such as ethanol, ether, acetone, etc., and can be miscible with it.
Furthermore, the volatility of bromohexane cannot be ignored. It will evaporate slowly at room temperature and pressure, and its special smell can be smelled in the air. And because of its certain flammability, there is a risk of burning in case of open flames and hot topics, so when storing and using, when avoiding fire sources and heat sources, operate with caution.
What are the chemical properties of Bromohexane?
Bromohexane is also an organic compound, which has the generality of halogenated hydrocarbons.
First, hydrolysis. In contact with water and catalyzed by alkali, bromohexane can undergo hydrolysis. In this process, bromine atoms are replaced by hydroxyl groups to form hexanol. Halogen atoms in halogenated hydrocarbons are more active and easily replaced by nucleophiles. The chemical equation for hydrolysis is: $C_ {6} H_ {13} Br + NaOH\ xrightarrow [] {H_ {2} O} C_ {6} H_ {13} OH + NaBr $.
Second, the property of elimination. When bromohexane is co-heated with an alcohol solution of a strong base, the elimination reaction can occur. The hydrogen bromide is removed from the molecule to form an olefin. This reaction follows the Zaitsev rule, that is, the hydrogen atom is mainly removed from the adjacent carbon atom with less hydrogen to form an olefin with more substituents on the double-bonded carbon. If the ethanol solution is co-heated with sodium ethanol, the chemical equation is: $C_ {6} H_ {13} Br + C_ {2} H_ {5} ONa\ xrightarrow [] {C_ {2} H_ {5} OH} C_ {6} H_ {12} + C_ {2} H_ {5} OH + NaBr $, and the resulting olefin is mainly 1-hexene or 2-hexene.
Third, the properties of reaction with metals. Bromohexane can react with certain metals, such as magnesium in an anhydrous ether environment, to form Grignard reagents. Grignard reagents are widely used in organic synthesis and can react with a variety of carbonyl-containing compounds to grow carbon chains and build complex organic molecular structures. The reaction formula is: $C_ {6} H_ {13} Br + Mg\ xrightarrow [] {anhydrous ether} C_ {6} H_ {13} MgBr $.
Fourth, the nature of the substitution reaction. In addition to hydrolysis, the bromine atom of bromohexane can also be replaced by other nucleophiles. If reacted with sodium cyanide, the bromine atom is replaced by a cyanyl group to form hexonitrile. This reaction can grow the carbon chain, and hexanitrile can be converted into various organic compounds after further reaction. The reaction equation is: $C_ {6} H_ {13} Br + NaCN\ xrightarrow [] {alcohol} C_ {6} H_ {13} CN + NaBr $.
In summary, the chemical properties of bromohexane hydrolysis, elimination, reaction with metals and nucleophilic substitution make it have important applications in the field of organic synthesis.
What chemical reactions is bromohexane commonly used in?
Bromohexane is often used in various reactions in organic chemistry. It is an important angle in nucleophilic substitution reactions. Nucleophilic reagents, such as hydroxyl ions, alkoxy ions, cyanogen ions, etc., can interact with bromohexane. When hydroxyl ions meet bromohexane, they are nucleophilic substituted, and the bromine atom is replaced by a hydroxyl group to obtain hexanol. When alkoxy ions react with bromohexane, corresponding ethers are produced. When cyanogen ions meet bromohexane, the product is nitrile, and subsequent hydrolysis results in a carboxylic acid of one carbon.
In the elimination reaction, bromohexane is also quite important. Under the action of strong bases, such as sodium ethanol, bromohexane can undergo elimination reactions to remove hydrogen bromide and produce hexene. This reaction can produce olefins, which are beneficial for organic synthesis. Olefins can be used as raw materials for many reactions, such as addition reactions.
In addition, bromohexane is also commonly used in organometallic reagents. Grignard reagents are prepared with magnesium and bromohexane. This reagent has high activity and can react with carbonyl compounds, such as alcaldes and ketones, to form alcohols. This reaction is an important means for growing carbon chains and building complex organic molecules. < Br >
Bromohexane is a commonly used compound in nucleophilic substitution, elimination and reaction of organometallic reagents. It has a significant position in the field of organic synthesis and helps chemists to prepare a variety of organic compounds.
What are the methods for preparing Bromohexane?
To prepare bromohexane, there are two methods. First, coheat hexanol with hydrobromic acid. This is a common method. The hydroxyl group in hexanol is replaced by the bromine ion in hydrobromic acid to obtain bromohexane. The reaction formula is as follows: $C_ {6} H_ {13} OH + HBr\ stackrel {\ Delta} {\ longrightarrow} C_ {6} H_ {13} Br + H_ {2} O $. When reacting, pay attention to the control of temperature. If it is too high, it is easy to cause side reactions, such as dehydration of hexanol to alkenes.
Second, the addition of hexene to hydrogen bromide. This is a typical reaction of olefins. Following the Markov rule, hydrogen in hydrogen bromide is added to the double-bonded carbon with more hydrogen, and bromine is added to the double-bonded carbon with less hydrogen to obtain bromohexane. The reaction formula is: $C_ {6} H_ {12} + HBr\ longrightarrow C_ {6} H_ {13} Br $. This reaction is relatively simple, and there are few side reactions, and the yield is quite high. However, when preparing, the purity of the raw material and the reaction conditions need to be strictly controlled to ensure the quality and quantity of the product.
What are the main uses of Bromohexane?
Bromohexane, as well as organic compounds, has a wide range of uses. In the field of organic synthesis, it is often a key raw material. Because of the activity of bromine atoms in its structure, it can cause a variety of chemical reactions.
One of them can be used to prepare alcohols. Bromohexane is treated with an appropriate alkali solution. After substitution reaction, the bromine atoms are replaced by hydroxyl groups to obtain hexanol. This hexanol is useful in flavors, solvents and other industries. In fragrances, it can add its unique smell; in solvents, it can help dissolve a variety of organic substances.
Second, in the preparation of ether compounds, bromohexane is also indispensable. React with alcohols under alkaline conditions to form corresponding ethers. In organic synthesis and industrial production, ethers are often used as excellent solvents because of their good solubility and relatively stable chemical properties.
Furthermore, bromohexane can be used to construct carbon-carbon bonds. By reacting with metal-organic reagents, such as Grignard reagents, hexyl groups can be introduced, thereby increasing the carbon chain and laying the foundation for the synthesis of complex organic molecules. This is of great significance in the field of drug synthesis, and the construction of many drug molecules depends on this method.
In addition, in the preparation of surfactants, bromohexane may also participate in it. After a series of reactions, surfactants with specific properties can be prepared, which can be used in daily chemicals, textiles and other industries to play the functions of emulsification, dispersion and solubilization.
In conclusion, bromohexane has important uses in many aspects of organic synthesis and chemical production due to its active chemical properties, promoting the development of related industries.