N-Octyl Bromide

Qiji Chemical

Specifications

HS Code	350788
Chemical Formula	C8H17Br
Molar Mass	193.12 g/mol
Appearance	Colorless to light yellow liquid
Odor	Characteristic odor
Density	1.118 g/cm³ (at 20 °C)
Boiling Point	201 - 204 °C
Melting Point	-55 °C
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in many organic solvents like ethanol, ether
Flash Point	78 °C
Refractive Index	1.453 (at 20 °C)

Packing & Storage

Packing	100 - gram bottle of N - Octyl Bromide, securely sealed for chemical storage.
Storage	N - Octyl Bromide should be stored in a cool, well - ventilated area away from heat sources and open flames. It should be kept in a tightly closed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances. Avoid storing in areas prone to flooding or high humidity to maintain its chemical integrity.
Shipping	N - Octyl Bromide is shipped in well - sealed, corrosion - resistant containers. It is handled as a hazardous chemical, following strict regulations. Shipments ensure proper insulation and secure packaging to prevent leakage during transit.

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General Information

Historical Development

"Historical Development of N-Octyl Bromide"
I have heard that all chemical substances have their origin and evolution. N-octyl bromide is no exception. In the past, chemical research was not as profound as it is today, and the understanding of such compounds was still shallow. However, as the years went on, various scholars worked tirelessly. At the beginning, only a little knowledge of its physical properties, and the preparation method was also simple.
After catching the later generations, science and technology gradually advanced, chemists worked hard to analyze its structure and optimize the preparation process. From simple method to exquisite. The application of N-octyl bromide in organic synthesis and other fields has gradually become widely known. Its historical development, like a trickle, converged into a river, from ignorance to clarity, leaving a deep impression on the path of chemistry, laying a solid foundation for future scientific research and industry.

Product Overview

About the product overview of N - Octyl Bromide
Nowadays, there is a thing called N - Octyl Bromide. It is an organic compound and has a wide range of uses in various fields of chemical industry.
Looking at its shape, it is a colorless to light yellow transparent liquid at room temperature, and it has a specific smell. Its properties are stable, but it can also be burned when exposed to open flames and hot topics. Be careful when using it.
Regarding its preparation, it is mostly obtained from n-octyl alcohol and hydrobromic acid through a specific chemical reaction. During the reaction, it is necessary to control the temperature and pressure to ensure a smooth reaction.
N - Octyl Bromide is used in the field of organic synthesis, often as an alkylation reagent to introduce octyl. In the pharmaceutical industry, it is an indispensable raw material for the synthesis of specific drugs; in materials science, it is also a key component for the preparation of special materials.
In summary, although N - Octyl Bromide is an ordinary chemical, it plays an important role in the chemical industry. Its research and application should be valued by my generation of chemical researchers.

Physical & Chemical Properties

N - Octyl Bromide is an organic compound. It has specific physical and chemical properties. Looking at its physical properties, at room temperature, it is a colorless and transparent liquid with a special odor. Its boiling point is quite high, about 198 - 201 ° C. This characteristic makes it stable in a liquid state under a specific temperature environment.
On its chemical properties, it is active to a certain extent because it contains bromine atoms. It can participate in many chemical reactions, such as nucleophilic substitution reactions. Bromine atoms are easily replaced by nucleophilic reagents, and then a variety of organic products are derived. And it has good solubility in organic solvents and can be miscible with a variety of organic solvents. This property provides a suitable environment for the reaction in organic synthesis experiments, which is conducive to the smooth progress of the reaction. It is of great significance for the research of organic chemistry and the preparation of related products.

Technical Specifications & Labeling

Nowadays, there is a technique for making N-Octyl Bromide, and its process specifications and identification (commodity parameters) are the key. To make this product, first clarify the quality and quantity of its raw materials, and operate according to the exact ratio.
The reaction device needs to be clean and suitable temperature. Control the temperature to a suitable degree, do not make it too high or too low, causing the reaction to be perverse. When reacting, stir well to make all the things blend properly.
After making, check its purity. Looking at its color, it should be clear and free of impurities; measuring its boiling, when it is in line with the established value. Measuring its density, it must also meet the specifications. The amount of impurities must be strictly controlled at the micro-end. In this way, Fang De Jia goods, the marked parameters are all the same as the measured, which can be trusted by the user.

Preparation Method

The preparation of n-octyl bromide (N-Octyl Bromide) involves raw materials and production processes, reaction steps and catalytic mechanisms. The raw materials are usually n-octyl alcohol and hydrobromic acid. In the reaction step, n-octyl alcohol and an appropriate amount of hydrobromic acid are placed in a reactor, sulfuric acid is added as a catalyst, and heating is heated to a suitable temperature, usually about 80 to 100 degrees Celsius. At this time, n-octyl alcohol reacts with hydrobromic acid, and the hydroxyl group is replaced by a bromine atom to form n-octyl bromide. During the reaction, it needs to be stirred continuously to make the reaction sufficient. After the reaction is completed, the impurities can be removed by subsequent treatments such as distillation separation, washing with water, and drying. Pure n-octyl bromide This preparation method requires accurate control of the conditions of each link to ensure product quality and yield.

Chemical Reactions & Modifications

Taste the wonders of chemical industry, the changes are endless. Today, in the case of N-Octyl Bromide, its chemical reaction and variability are considerable.
N-Octyl Bromide, when it encounters a base, it undergoes a substitution reaction, and the bromine atom is replaced by a hydroxyl group to form a genus of octanol. This reaction is also very important to control the conditions. If the temperature is high, it will be fast, but if it is too high, it will cause side effects.
In the process of organic synthesis, when it encounters an olefin, it can be added to expand its carbon chain and increase its structure. This is the usual reaction.
As for variability, due to the activity of bromine atoms, new radicals can be introduced, making physical properties very different. Or change its dissolution, or change its boiling, all of which are alienated in response. Good inspection of its response, precise control of its change, the chemical industry, a few progress.

Synonyms & Product Names

"N-Octyl Bromide" is a chemical substance, and its synonymous name and trade name are quite important in my field of research.
This compound, or its name is n-octyl bromide. Its name is "n-octyl bromide", because in the molecular structure, the bromine atom is connected to a straight-chain alkyl group containing eight carbons, which is n-octyl, hence the name.
As for the trade name, the industry may have different names. In the city of chemical trade, there may be a specific trade name added to make this product different from his family. However, regardless of its synonymous name or the name of the product, it all refers to the same chemical "N-Octyl Bromide". On the occasion of research, it is necessary to understand its various terms in order to obtain accurate information, correct in experiments and applications, avoid confusion, and promote the smooth development of chemical research and industry.

Safety & Operational Standards

N - Octyl Bromide, organic compounds are also used. Safety and operating practices are of paramount importance during its experimental preparation and use.
When preparing, it should be done in a well-ventilated environment. Because of its volatility, if inhaled in excess, it may damage the respiratory tract and nervous system. Experimenters wear protective clothing, goggles and gloves to prevent contact.
The operation process must be accurate. When measuring the reactants, the gauges used must be clean and accurate to ensure that the proportions of each substance are appropriate. When mixing the reactants, the stirring rate should also be appropriate to allow the reaction to proceed evenly. When heating the reaction system, temperature control is critical. The reaction of N-Octyl Bromide is quite sensitive to temperature. If the temperature is too high, or side reactions occur, it will affect the purity of the product; if the temperature is too low, the reaction will be slow and time-consuming.
Product storage is also exquisite. It should be placed in a cool, dry and ventilated place, away from fire sources and oxidants. Because of its flammability, it can burn in case of open flames and hot topics, causing safety accidents.
When using N-Octyl Bromide for subsequent reactions, the same specifications must be followed. The reaction device is firmly established to ensure good air tightness and prevent product leakage. After the experiment, the residual products and waste should be properly disposed of in accordance with relevant regulations and should not be discarded at will to avoid polluting the environment.
In conclusion, N-Octyl Bromide must be treated in strict accordance with safety and operating standards, from preparation to use, to storage and waste disposal, in order to ensure the safety and smooth operation of the experiment, and to ensure the safety of personnel and the environment.

Application Area

N-Octyl Bromide, which is n-octyl bromide, has wonderful uses in many fields. In the field of organic synthesis, it is often used as an alkylation agent. In terms of ancient recipes, this is due to its active nature, combining with many compounds, adding alkyl groups to it, in order to form a new organic structure. For example, when preparing fragrances, N-Octyl Bromide can be used to introduce specific alkyl groups to change the aroma characteristics of fragrances and make their taste more subtle.
In the field of pharmaceutical research and development, it is also widely used. It can be used as a key intermediate to participate in the construction of drug molecules. Although people did not have the knowledge of medicine in the past, by analogy, it can also be known that it is important in the synthesis of unique pharmacodynamic structures. Based on it, after several steps of reaction, a substance with specific pharmacological activity can be obtained, which lays the foundation for a good medicine for healing diseases.
In the field of materials science, N-Octyl Bromide can be used to synthesize materials with special properties. Like an ancient creation, using it as an element and combining with other things, materials with specific properties can be made, or their toughness can be increased, or their conductivity can be changed to meet different needs.

Research & Development

The recent research on the production of N-Octyl Bromide has been quite advanced. At the beginning, it was difficult to make this product. The method of its transformation has not been refined, the yield is quite low, and the quality is not pure.
All researchers have worked hard and tried repeatedly. Or change its raw materials, or adjust its method, or change its equipment. After years of work, it has gradually become successful. Today's method is good, the yield has greatly increased, and the quality is also pure.
Looking at its use, it is beneficial in all industries. The genus of medicine can be used as an adjuvant; the field of chemical industry can be used as a raw material. From this perspective, the progress of studying this thing is not only the completion of the art, but also helpful to all karma. In the future, we should be more diligent and look forward to new gains, so as to promote its wide use and make all karma more prosperous.

Toxicity Research

Since modern times, chemical refinement has advanced, and all kinds of substances have entered the field of research. In this case, N-Octyl Bromide, the study of its toxicity is quite important.
Detailed examination of N-Octyl Bromide, its sexual activity, in experiments, often observed its impact on various organisms. Take white mice as a test, feeding food containing this thing, not long after, the white mice gradually showed fatigue and reduced their diet. Its hair is lost and its movement is slow, all of which are signs of toxicity.
And in plants, irrigated with N-Octyl Bromide dissolved water, the growth of plants is blocked, the leaves gradually wilt, the flowering period is delayed, and even wither. This shows that its toxicity is strong and can harm life.
Studying the toxicity of this product is designed to warn the world and use it with caution to prevent it from causing harm to the ecology and endangering people's lives. When making future generations use this product, weigh the pros and cons, avoid harm and seek benefits, which is the original intention of studying toxicity.

Future Prospects

There is a thing today, named N-Octyl Bromide. Its properties are quite promising in the way of chemical research. Looking at the results of past research, it can be the foundation of all paths.
Looking forward to the future, one of them may be very promising for the system of new materials. With its properties, it may be able to participate in the modification of materials, so that materials have special properties, such as the genus of toughness and corrosion resistance. Second, in the field of medicine, there are also new machines. Or it can be used as a medium for medicine, to help drugs reach their intended position and increase their efficacy.
Although there may be thorns in the road ahead, with the perseverance and diligent research of our generation's research people, we will be able to explore its endless potential, expand its broad path, and be used by the world to benefit everyone, so as to recognize the magnificent future of this material future.

Frequently Asked Questions

What are the main uses of N-Octyl Bromide?

N-Octyl Bromide, or n-octyl bromide, has a wide range of uses.
It is an important starting material in the field of organic synthesis. It can react with many nucleophilic reagents through nucleophilic substitution reactions. For example, by reacting with alkoxides, ether compounds can be formed, which is a common way to prepare ethers. Alcohol and n-octyl bromide can be catalyzed by bases to generate corresponding ethers, which are often used in organic synthesis to construct carbon-oxygen bonds. It can also react with cyanides to form nitriles, which can be later converted into carboxylic acids through reactions such as hydrolysis, providing a method for synthesizing carboxylic acids with specific structures.
In the preparation of surfactants, n-octyl bromide also has important functions. It can react with compounds containing hydrophilic groups such as nitrogen and oxygen to generate surfactants with amphiphilic structures. For example, it reacts with amines to form quaternary ammonium salt surfactants. Such surfactants are widely used in daily chemical, textile and other industries. They can be used as emulsifiers and dispersants in daily chemical products to uniformly mix oil and water phases and improve product stability. In the textile industry, they can be used as leveling agents to distribute dyes evenly on fabrics.
In the field of medicine, n-octyl bromide is involved in the synthesis of some pharmaceutical intermediates. For some molecules with specific pharmacological activities, the carbon chain structure provided by n-octyl bromide needs to be introduced into the synthesis route to optimize the physical and chemical properties of the drug molecule, such as fat solubility, which in turn affects the absorption, distribution, metabolism and excretion process of the drug, and improves the efficacy of the drug.
In addition, in the field of materials science, it can be used to prepare functional materials. For example, by reacting with specific polymer monomers, the polymer is modified to impart new properties to the material, such as improving the surface wettability and flexibility of the material.

What are the physical properties of N-Octyl Bromide?

N-Octyl Bromide is an organic compound. Its physical properties are quite characteristic, let me tell you one by one.
N-Octyl Bromide is a colorless to light yellow liquid at room temperature, and it is clear and translucent. Its smell is unique, slightly irritating, and you can feel it when you smell it. Regarding the melting point, the melting point is about -55 ° C, and the boiling point is between 198 and 200 ° C. This characteristic makes it appear in different physical states under different temperature environments.
Furthermore, its density is greater than that of water, about 1.118g/cm ³. When mixed with water, it can be seen that it sinks to the bottom of the water. In terms of solubility, n-octyl bromide is insoluble in water, but it can be miscible with most organic solvents such as ethanol, ether, acetone, etc. This is due to the principle of "similar miscibility", and its organic structure makes it have good affinity with organic solvents.
The vapor pressure of n-octyl bromide is low, the volatility is relatively weak, and it is relatively stable at room temperature and pressure. However, it is still flammable in case of open flames and hot topics, and may produce harmful gases such as hydrogen bromide when burned.
The above is the main physical properties of n-octyl bromide.

What is the chemistry of N-Octyl Bromide?

N-octyl bromide is an organic compound with unique chemical properties. This substance has high chemical activity and is widely used in the field of organic synthesis.
From the perspective of nucleophilic substitution reaction, the bromine atom of N-octyl bromide has high activity and is vulnerable to attack by nucleophilic reagents, resulting in nucleophilic substitution reaction. If it encounters sodium alcohol, ether compounds can be formed; when it interacts with sodium cyanide, nitrile substances are formed. This reaction mechanism is based on the fact that the nucleophilic tester attacks the positively charged α-carbon atom, and the bromine ion is separated as a leaving group, thus completing the substitution process.
In the elimination reaction, N-octyl bromide can undergo elimination reaction in a strong alkali environment to form olefins. This reaction goes through the E1 or E2 mechanism, depending on the reaction conditions. If the strength of the base is high, the concentration of the reactants is high and the reaction temperature is suitable, the E2 mechanism is mostly carried out, that is, the bromine ion leaves the hydrogen atom on the adjacent carbon atom at the same time to form a double bond.
N-octyl bromide can also participate in metal-organic reactions. If reacted with magnesium, Grignard reagent can be obtained. This Grignard reagent is an extremely important intermediate in organic synthesis. It can react with many carbonyl compounds such as aldides, ketones, and esters to form carbon-carbon bonds, and greatly expand the pathways and product types of organic synthesis.
Because of its active chemical properties, N-octyl bromide needs special attention when storing and using. It should be placed in a cool, dry and well-ventilated place, away from fire sources and oxidants, to prevent dangerous chemical reactions. In short, N-octyl bromide occupies an important position in the field of organic synthesis chemistry due to its special chemical properties, promoting the development of organic compound preparation and related fields.

What are the synthesis methods of N-Octyl Bromide?

The methods for preparing n-octyl bromide (N-Octyl Bromide) are as follows.
One is to use n-octyl alcohol and hydrobromic acid as raw materials. The two are mixed, and under the condition of sulfuric acid catalysis, a co-thermal substitution reaction occurs. The hydroxyl group in n-octyl alcohol is attacked by bromine ions in hydrobromic acid, and the hydroxyl group is replaced by bromine atoms, resulting in n-octyl bromide. During the reaction process, the role of sulfuric acid is to promote the reaction to proceed in the direction of product formation and speed up the reaction rate. However, this process needs to be controlled by temperature. If the temperature is too high, it is easy to produce side reactions, such as dehydration of alcohols to alkenes.
Second, n-octane can react with bromine under light or in the presence of This is the free radical substitution reaction mechanism. Light or initiator prompts bromine molecules to split into bromine free radicals, bromine free radicals attack n-octane molecules, capture hydrogen atoms, generate n-octane free radicals, n-octane free radicals and then interact with bromine molecules to obtain n-octane bromide. This method can only proceed smoothly under sufficient light or an appropriate amount of initiator. However, the reaction products are often complex. In addition to n-octane bromide, other brominated products will be generated, which need to be carefully separated and purified.
Third, react with n-octane alcohol and phosphorus tribromide. The hydroxyl group of n-octanol reacts with phosphorus tribromide, and the phosphorus atom nucleophilic attacks the hydroxyl oxygen atom. After a series of changes, the hydroxyl group is replaced by the bromine atom to form n-octyl bromide, and phosphoric acid is produced at the same time. This reaction condition is relatively mild, the yield is considerable, and there are few side reactions. The operation is relatively simple, and it is quite commonly used in laboratory and industrial preparation.
All these methods have their own advantages and disadvantages. In actual preparation, it is necessary to consider the cost of raw materials, reaction conditions, product purity and many other factors according to specific needs to choose the appropriate method.

What are the precautions for N-Octyl Bromide during storage and transportation?

N-octyl bromide is an organic compound. When storing and transporting it, many matters must be paid attention to.
When storing it, the first choice of environment. It must be placed in a cool and ventilated warehouse. Due to excessive temperature or its volatilization, it may even cause dangerous chemical reactions. And the humidity of the warehouse must also be controlled within an appropriate range to prevent moisture from affecting the quality. In addition, this compound is toxic and flammable. When stored separately from oxidants, acids, bases and other substances, it must not be mixed, otherwise it may cause severe reactions and endanger safety. The storage place should also be equipped with suitable materials to contain leaks, in case of leakage, it can be dealt with in time.
As for transportation, the packaging must be tight and stable to ensure that it will not be damaged and leaked during transportation. Transportation vehicles need to be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. During driving, drivers must drive with caution and avoid violent operations such as sudden braking and sharp turns to prevent damage to the packaging. During transportation, drive according to the specified route and do not stop in densely populated areas and residential areas. Transport personnel should also be familiar with its nature and emergency treatment methods. Once a situation occurs, they can respond quickly and correctly to ensure transportation safety.