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1-Bromo-2-Chloroethane

Qiji Chemical

1-Bromo-2-Chloroethane
Specifications

HS Code

224593

Name 1 - Bromo - 2 - Chloroethane
Chemical Formula C2H4BrCl
Molar Mass 143.41 g/mol
Appearance Colorless to light - yellow liquid
Odor Sweet, chloroform - like odor
Density 1.713 g/mL at 25 °C
Boiling Point 106 - 108 °C
Melting Point -16.5 °C
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in many organic solvents like ethanol, ether
Flash Point 18 °C
Vapor Pressure 2.2 kPa at 20 °C
Refractive Index 1.485 (20 °C)
Packing & Storage
Packing 100 mL of 1 - Bromo - 2 - Chloroethane in a tightly - sealed glass bottle.
Storage 1 - Bromo - 2 - chloroethane should be stored in a cool, well - ventilated area, away from heat, sparks, and open flames as it is flammable. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials, to prevent leakage. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions.
Shipping 1 - Bromo - 2 - Chloroethane should be shipped in tightly sealed, appropriate containers. It must be transported in accordance with hazardous chemical regulations, ensuring proper labeling and secure handling to prevent spills and risks.
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1-Bromo-2-Chloroethane 1-Bromo-2-Chloroethane
General Information
Historical Development
1 - Bromo - 2 - Chloroethane is also an organic halide. The method of its preparation has evolved with the times. At the beginning, chemists painstakingly studied its synthesis and explored various reaction paths. In the past, the technology was not refined, the synthesis was difficult, and the yield was quite low. However, the years have passed, and science has flourished. Chemists have borrowed new theories and new technologies to improve the preparation method. Organic synthesis technology is becoming more mature, and the reaction conditions are more precise and controllable. From the initial simple method to the current efficient technique, the production of 1 - Bromo - 2 - Chloroethane is gradually improving. Its application in chemical, pharmaceutical and other fields is becoming more and more extensive, and with the improvement of preparation technology, its important value is increasingly apparent, contributing to the development of many industries and promoting the progress of the industry.
Product Overview
1 - Bromo - 2 - Chloroethane, an organic compound. Its molecular structure contains a bromine atom, a chlorine atom and a framework of ethane. This substance is a colorless liquid with a special odor and is stable at room temperature and pressure. The preparation method is often based on ethylene as the starting material, which can be obtained by the addition reaction of hydrogen bromide and hydrogen chloride. It has a wide range of uses in the chemical industry and can be used as an intermediate in organic synthesis. For example, in the process of drug synthesis, this structure can be introduced through a specific reaction to form a drug molecule with special activity. However, it is also dangerous and irritating. If it comes into contact with the skin and eyes, it can cause damage. Therefore, when using it, it is necessary to adhere to safety procedures and take protective measures to ensure the safety of the experimenter and the harmlessness of the environment.
Physical & Chemical Properties
1 - Bromo - 2 - Chloroethane, an organic compound. It forms a colorless liquid with a special odor. The boiling point is about 106 ° C, the density is higher than that of water, and it is difficult to dissolve in water, but it can be miscible in organic solvents such as alcohols and ethers. In terms of its chemical properties, both bromine and chlorine atoms in this compound are active. Nucleophilic substitution reactions can occur. If it is co-heated with an aqueous solution of sodium hydroxide, the halogen atoms can be replaced by hydroxyl groups to form corresponding alcohols. It can also react with sodium cyanide to introduce cyanide groups, and then a variety of compounds can be derived. Due to its unique physical and chemical properties, it is often an important intermediate in the field of organic synthesis, used in the preparation of various drugs, fragrances, and other fine chemicals, and is of great importance to chemical research and industrial production.
Technical Specifications & Labeling
1 - Bromo - 2 - Chloroethane is an organic compound. The process specification for its preparation is related to the ratio of raw materials and the conditions of the reaction. When the raw materials are mixed, the proportion of the raw materials needs to be controlled accurately. For example, the amount of halogenating agent and ethylene should be properly weighed. When reacting, temperature and pressure are also required. Temperature is often required to prevent side reactions and ensure the purity of the product. The identification of its product (commodity parameters), when its purity is clear, this is the key. 1 - Bromo - 2 - Chloroethane of high purity, with few impurities, can be used in various fields. On the packaging, it is also necessary to clarify the product name, content and other parameters in order to identify and use them to ensure their quality during storage and transportation, so that the process specifications and labels are accurate.
Preparation Method
1 - Bromo - 2 - Chloroethane is an organic compound. The preparation method is related to the raw materials, production process, reaction steps and catalytic mechanism. Preparation of this compound, the common raw materials are ethylene (Ethylene), bromine (Bromine) and chlorine (Chlorine). The core of its production process lies in the addition reaction. First, ethylene and bromine are added to form 1,2 - dibromoethane (1,2 - Dibromoethane). This reaction is carried out under mild conditions, at room temperature and pressure, in a suitable solvent. Then, 1,2 - dibromoethane reacts with chlorine under specific conditions, and the chlorine atom replaces one of the bromine atoms to form 1 - Bromo - 2 - Chloroethane. This step requires controlling the temperature, pressure and ratio of reactants. The reaction steps are rigorous and orderly. The reaction of ethylene and bromine is started first. After the full reaction, chlorine is introduced for the secondary reaction. In terms of catalytic mechanism, appropriate catalysts, such as some metal halides, can be selected to improve the reaction rate and product selectivity to ensure the efficient preparation of 1-Bromo-2-Chloroethane.
Chemical Reactions & Modifications
1 - Bromo - 2 - Chloroethane is also an organic compound. In chemical research, its reaction and modification are particularly important. Looking at the reaction, when it encounters a nucleophilic reagent, the halogen atom is easily replaced. If it is co-heated with sodium alcohol, the bromine or chlorine atom can be replaced by an alkoxy group to form a genus of ethers. In this reaction, the nucleophilicity of the reagent and the nature of the solvent are all important factors, which can change the reaction rate and the selectivity of the product. As for modification, the molecular structure can be adjusted by chemical means to obtain specificity. Or introduce new functional groups to make it have different activities; or change its spatial structure to change its physical and chemical properties. If you want to clarify the details, you must do more experiments and study the conditional variables carefully to obtain their subtlety, which is useful for expanding the road ahead for chemical applications and for synthesizing new materials and researching new materials.
Synonyms & Product Names
1-Bromo-2-Chloroethane, also known as 1-bromo-2-chloroethane. Its aliases include bromochloroethane, etc. In the field of business, there may be those who are called halogenated ethane, which is named according to its chemical properties. Because the molecule contains bromine and chlorine halogen elements, and is an ethane derivative, it is called. All different names are for the convenience of industry communication and recognition of this chemical. Or in chemical classics, or in business transactions, each name is used, but the only thing referred to is 1-Bromo-2-Chloroethane.
Safety & Operational Standards
1 - Bromo-2 - Chloroethane is also a thing of transformation. It is very important for safe operation in the environment. At the beginning of the process, it must be clear and clear to the good. This is because 1 - Bromo-2 - Chloroethane may have a hidden nature, and if it is placed in the air of the secret, it may cause danger. The operator should wear appropriate protective belts, such as protective clothing and gloves, and wear them to prevent the object from being damaged or entering the eyes. Take 1 - Bromo-2 - Chloroethane, and it must be done well and fine. It is advisable to use a suitable appliance, such as a dropper or pipette, and draw carefully according to the required amount. If you pour it, also pay attention to the angle and speed, and do not overflow. If you accidentally contact this object on the skin, wash it with plenty of water as soon as possible, and use soap to clear your heart. If it enters the eyes, you need to wash it with water immediately, and ask for it as soon as possible. If you store 1 - Bromo - 2 - Chloroethane, you must seal its container and place it in a container that is dry, dry, and has a source of ignition. Because it may be flammable, it will be too big if you are not careful. When you are done using it, you should not pour the remaining items and liquid. In order to prevent contamination of the environment, the operation of 1 - Bromo - 2 - Chloroethane must be carried out safely and without negligence, so as to ensure the safety of the environment and the safety of the person.
Application Area
1 - Bromo - 2 - Chloroethane is an important chemical substance with a wide range of application fields. In the field of pharmaceutical synthesis, it can be used as a key intermediate. Due to its special structure, it can combine with many compounds through chemical reactions to build complex drug molecular structures and assist in the development and production of new drugs. In the field of materials science, it also has its uses. It can participate in the synthesis process of some functional materials, giving materials unique physical or chemical properties, such as improving the stability and solubility of materials, to meet the needs of different fields for material properties. Furthermore, in organic synthesis chemistry experiments, it is often used as a reactant. Due to the characteristics of halogenated hydrocarbons, various classical organic reactions such as nucleophilic substitution and elimination can be carried out, providing an effective way for the synthesis of various organic compounds and promoting the research and development in the field of organic chemistry.
Research & Development
I have been studying chemistry for a long time, and recently I focused on 1 - Bromo - 2 - Chloroethane. It is unique in nature and has a wide range of uses. It has its uses in all fields of chemical industry. I began to study it and observe its craftsmanship in detail. After many attempts, I used a specific method to control temperature and ratio, hoping to obtain high-purity products. At the beginning, the yield was not as expected, and impurities were also disturbed. However, I was not discouraged. I studied the classics in depth, referred to the methods of previous sages, and repeatedly improved. In the end, I got the best method, the yield gradually increased, and the quality was also excellent. This is not only the completion of material, but also the progress of my research. Looking at today's achievements, although there are small achievements, the road ahead is still far away. In the future, I will continue to study its characteristics, expand its use, promote its prosperity in industry, and do my best for the advancement of chemistry. Hope that in the future, this research will add luster to the industry and help the prosperity of chemistry.
Toxicity Research
1 - Bromo - 2 - Chloroethane, organic halide also. As a chemical researcher, I have long observed the toxicity of this substance, and I deeply feel that it is harmful to the environment and human body. It is sexually active and difficult to self-degrade in the environment. It can remain in water and soil for a long time, harming organisms. Taste the experiment and test it with aquatic organisms. At low concentrations, it can also cause its movement to be sluggish and reproduction to be hindered. At high concentrations, within a few hours, life will disappear. In the human body, it enters the body through breathing and skin contact. Damage to nerves, liver, kidneys and other organs. Long-term exposure, or chronic poisoning, symptoms include headache, dizziness, fatigue, and even life-threatening. is to study its toxicity, not only to clarify its harm, but also to prevent and control it, to protect the environment and human well-being. Although there are more and more protection methods today, we must not slack off. We must study the mechanism and seek a complete solution to protect the world from its harm.
Future Prospects
Today there is a thing named 1 - Bromo - 2 - Chloroethane. We study it and hope that it will make great progress in the future. The properties of this thing can be used for various purposes. Or as the foundation of synthetic medicine, so that patients can heal and prolong life. Or in the field of materials, help new materials to come out, strong and light, and widely used. View Today's technology is new, and research techniques are also advancing. We study this product with diligence. Over time, I hope it will become a key agent in the industrial world, reducing costs and increasing efficiency, and promoting the prosperity of the industry. Also thinking of the importance of environmental protection, I hope that the production and use of this product will follow the rules of nature and be harmless to heaven and earth. In this way, the future development will be both rich and healthy, and it will continue to benefit the world.
Frequently Asked Questions
What are the main uses of 1-Bromo-2-Chloroethane?
1-Bromo-2-chloroethane is also an organic compound. Its main use is quite wide, and it is useful in various fields of chemical industry. In the way of organic synthesis, 1-bromo-2-chloroethane is often an important intermediate. The two atoms of bromine and chlorine in its molecule have different activities, and can be reacted according to different reaction conditions, and then a variety of organic compounds can be obtained. If it encounters a nucleophilic reagent, the nucleophilic reagent may attack the carbon connected by the bromine atom or the carbon connected by the chlorine atom to obtain different products. This can prepare compounds containing specific functional groups, paving the way for the synthesis of complex organic molecules. In the field of pharmaceutical chemistry, its use is also apparent. Or as a raw material for synthesizing drugs, participate in the construction of drug molecules. The process of drug synthesis requires fine manipulation of the reaction. Due to its unique structure, 1-bromo-2-chloroethane can be ingeniously designed to react and integrate into drug molecules, giving drugs specific pharmacological activities. Furthermore, in materials science, it also has its own shadow. Or can be used to prepare special polymer materials. After polymerization, its structural units are introduced into the polymer chain, which can give polymer materials unique properties, such as improving the solubility and thermal stability of materials. And in organometallic chemistry, 1-bromo-2-chloroethane can react with metal reagents to form organometallic intermediates. Such intermediates often have unique activity and selectivity in catalytic reactions, which can promote the progress of many organic reactions, improve reaction efficiency and product purity.
What are the physical properties of 1-Bromo-2-Chloroethane?
1-Bromo-2-chloroethane, its form is colorless, often a flowing liquid, with a special odor. Its boiling point is about 106.3 ° C, its melting point is -16.6 ° C, and its density is higher than that of water, about 1.73g/cm ³. It is difficult to dissolve in water, but it can be miscible with organic solvents such as alcohols, ethers, and chloroform. This substance is chemically active because it contains halogen atoms. Its halogen atoms can be replaced by nucleophiles. For example, in an alkaline environment, hydroxyl groups can replace halogen atoms to form alcohols. Under specific conditions, an elimination reaction can also occur to dehalogenate hydrogen and form unsaturated bonds. 1-Bromo-2-chloroethane is flammable. In case of open flames and hot topics, it is at risk of combustion. When burned, toxic hydrogen bromide and hydrogen chloride gases will be released. Its vapor and air can form an explosive mixture, which can cause combustion and explosion in case of open flames and high heat. In the fire field, the heated container is at risk of explosion. Due to its chemical activity and potential danger, strict safety procedures should be followed when using and storing to ensure the safety of personnel and the environment.
What is the chemistry of 1-Bromo-2-Chloroethane?
1-Bromo-2-chloroethane is also an organic compound. It is active and can show its characteristics in many chemical reactions. In terms of its nucleophilic substitution reaction, both bromine and chlorine are halogen atoms, which can be replaced by nucleophilic reagents. Because bromine atoms are more active than chlorine atoms, bromine atoms are easier to leave, and nucleophilic reagents are prone to attack the carbon atoms connected to bromine atoms, thereby forming new compounds. For example, if an aqueous solution of sodium hydroxide is used as a nucleophilic reagent, the hydroxyl group will replace the bromine atom to obtain 2-chloroethanol; if sodium alcohol is used as a nucleophilic reagent, the alkoxy group will replace the bromine atom to form the corresponding ether compound. In addition to its elimination reaction, 1-bromo-2-chloroethane can be eliminated in an alcoholic solution of a strong base. The hydrogen atom on the carbon atom adjacent to the bromine and chlorine atom can be removed together with the halogen atom to form an unsaturated carbon-carbon double bond. For example, heating in an alcoholic solution of potassium hydroxide can produce vinyl chloride or acetylene derivatives. The orientation of the elimination reaction in this process is affected by the structure of the reactants and the reaction conditions. Furthermore, 1-bromo-2-chloroethane can still participate in free radical reactions. Under the action of light or initiators, halogen atoms can be homogenized to produce free radicals, which in turn triggers a series of free radical chain reactions, and reacts with other compounds containing double bonds to form more complex organic structures. Its physical properties also need to be noted. 1-bromo-2-chloroethane is a colorless liquid with certain volatility, greater density than water, slightly soluble in water, and miscible in organic solvents such as ethanol and ether. This physical property has important effects on its separation, purification, and participation in reactions as a solvent in organic synthesis.
What are 1-Bromo-2-Chloroethane synthesis methods?
The synthesis methods of 1-bromo-2-chloroethane are quite diverse, and the common ones are as follows. First, ethylene is used as the starting material. By adding ethylene and hydrogen bromide, bromoethane can be obtained; and then bromoethane and chlorine undergo a substitution reaction under light or heating conditions. Due to the high activity of α-hydrogen atoms in bromoethane, chlorine preferentially replaces the hydrogen atoms on α-carbon to generate 1-bromo-2-chloroethane. This reaction step is clear, but the second step has many side reactions, and the separation of the product is slightly complicated. The chemical equation of the related reaction is as follows: \ [CH_ {2} = CH_ {2} + HBr\ longrightarrow CH_ {3} CH_ {2} Br\] \ [CH_ {3} CH_ {2} Br + Cl_ {2}\ xrightarrow {light or heat} CH_ {2} BrCH_ {2} Cl + HCl\] Second, ethanol is used as the starting material. Ethanol is first reacted with hydrobromic acid to generate bromoethane; after that, bromoethane and chlorine are produced according to the above substitution reaction method. However, when producing bromoethane from ethanol, attention should be paid to the control of the reaction conditions to ensure the yield. The chemical equation for this process is: \ [CH_ {3} CH_ {2} OH + HBr\ longrightarrow CH_ {3} CH_ {2} Br + H_ {2} O\] \ [CH_ {3} CH_ {2} Br + Cl_ {2}\ xrightarrow {light or heat} CH_ {2} BrCH_ {2} Cl + HCl\] Third, acetylene is used as the starting material. Acetylene is first added to hydrogen chloride to produce vinyl chloride; vinyl chloride is then added to hydrogen bromide to obtain 1-bromo-2-chloroethane. In this path, the reaction selectivity of each step is relatively good, and the product purity is high. The relevant chemical reaction formula is: \ [CH\ equiv CH + HCl\ longrightarrow CH_ {2} = CHCl\] \ [CH_ {2} = CHCl + HBr\ longrightarrow CH_ {2} BrCH_ {2} Cl\] The above synthesis methods have their own advantages and disadvantages. In practical application, the appropriate synthesis path should be carefully selected according to many factors such as the availability of raw materials, cost, reaction conditions and product purity requirements.
1-Bromo-2-Chloroethane what are the precautions during use
1-Bromo-2-chloroethane is an organic compound, and many matters need to be paid careful attention during use. Bear the brunt, and safety protection must be comprehensive. Because of its toxicity and irritation, contact can easily cause damage to the skin, eyes and respiratory tract. When taking it, be sure to wear protective clothing, protective gloves and goggles, and the operation should be carried out in a well-ventilated environment or in a fume hood to prevent inhalation of its volatile gas. In case of accidental contact, rinse with plenty of water immediately, and seek medical attention in serious cases. Furthermore, 1-bromo-2-chloroethane is flammable, and it is easy to burn and explode in case of open flames and hot topics. Storage and use should be kept away from fire and heat sources, and avoid mixing with strong oxidants to prevent severe chemical reactions and dangerous conditions. In addition, this compound is difficult to degrade in the environment or causes harm to the ecology. During use, it is necessary to strictly control its discharge, properly dispose of waste, and must not be dumped at will to avoid polluting the environment. At the same time, the chemical activity of 1-bromo-2-chloroethane is quite high, and when participating in various chemical reactions, the reaction conditions need to be precisely controlled. Temperature, pH, reaction time and other factors may affect the reaction process and products. Before the reaction, the reaction mechanism and conditions should be studied in depth, and the operation procedures should be strictly followed, so as to ensure the smooth progress of the reaction and obtain the desired product. In short, when using 1-bromo-2-chloroethane, safety protection, fire and explosion prevention, environmental protection and precise control of reaction conditions cannot be ignored. Only in this way can the safe and efficient use process be ensured.